Flow cytometry gating strategy for MDSC. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 3. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 4. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

“…Enzyme kinetics results suggest that the improvement in enzyme performance largely stems from the decrease in enzyme–substrate affinity along the substrate transfer pathway. …”

The minimal data set. by Wenya Zhu (13957497)

“…However, the extensive use of insecticides poses a significant threat to the survival and efficacy of <i>T. ostriniae</i>. …”

S1 Fig - Population genetic diversity of <i>Schistosoma japonicum</i> arises from the host switching in the life cycle by Juan Long (4017317)

Cataract induction does not affect hunting behaviour in optimal light conditions (left panels) but causes impairments in challenging light environments (right panels). by Amartya T. Mitra (14043115)

“…Similarly, under bright and UV light, we did not detect differences in hunting success (E,G; <i>n</i>_{<i>control</i>} = 12, <i>n</i>_{<i>lens3RNAi </i>}= 23, <i>p</i>_horizontal = 0.28, <i>p</i>_vertical = 0.23), but observed a weak (nonsignificant) decrease in the hunting success of treatment individuals under dim white light (F,H; <i>n</i>_{<i>control</i>} = 13, <i>n</i>_{<i>lens3RNAi </i>}= 22, <i>p</i>_horizontal = 0.22, <i>p</i>_vertical = 0.42).…”

Effect size distribution and intersections of transcript usage response upon stimulation with <i>M</i>. <i>leprae</i> sonicate by T1R-free (LEP) and T1R-destined (T1R) leprosy pati... by Wilian Correa-Macedo (11813183)

“…<p>(<b>A</b>) Strip plot presenting the distribution of the mean fitted proportion difference (PΔ) between stimulated and non-stimulated samples by group. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…In this work, we report a fluorescence-based high-throughput screening method for OER catalysts. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…In this work, we report a fluorescence-based high-throughput screening method for OER catalysts. …”

Rat partial phase response curve obtained from entrainment protocol. by Xian Chen (107385)

Differentially used transcripts (DUT) for T1R and LEP groups suggest dysregulation of inflammatory circuitry in T1R. by Wilian Correa-Macedo (11813183)

“…Next, DUT with non-significant changes were assigned PΔ = 0. Given that no gene ontology (GO) or pathway enrichments were found, we searched the annotated function of each implicated gene in the GO, Reactome and KEGG databases. …”

Amino acid metabolic pathways are influenced by the NC1 POM cycle over expression. by Bonnie A. McNeil (22331601)

“…Box and whisker plots of selected metabolites that displayed significant increase or decrease in the NC1 POM cycle producing strain (NC), red boxes, or empty vector producing strain (YC) green boxes. …”

Layout of the virtual environment. by Stephen H. Fairclough (7156868)

“…The passing of time has been perceived to significantly slow in stressful situations, such as accidents or virtual threats. …”

The number of sampling cercariae and snails affected the coverage of alleles. by Juan Long (4017317)

Participants’ view of the virtual environment. by Stephen H. Fairclough (7156868)

“…The passing of time has been perceived to significantly slow in stressful situations, such as accidents or virtual threats. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”