First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Data Sheet 1_Shifts in soil microbial and nematode communities over progression of pine wilt disease occurring in Pinus koraiensis stands.pdf by Siyu Tian (9874001)

“…Consequently, we observed a lower inter-kingdom network complexity in the soil community of the pines following the PWD, in which the bacterial networks decreased but fungal networks increased in complexity. …”

Table 1_Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide.docx by Junyong Wang (3807964)

“…The half-life of YTP in plasma is significantly longer than that of YW12D and TP5. YTP also displays an improved ability to protect the host from CTX-induced weight loss and thymus and spleen indices decrease than YW12D and TP5. …”

Data Sheet 1_Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.zip by Yanqing Ren (2080156)

“…Weighted standardized mean differences (SMDs) and 95% confidence intervals (CIs) for α-diversity index were estimated using a random effects model. …”

Rescue of <i>pbp1</i>-KD phenotypes using CRISPRi trans-complementation. by Gregory A. Harrison (16639446)

“…Dots indicate individual cells, and the larger, outlined symbols represent the mean cell length from each replicate. The mean and standard deviation were calculated across replicates; statistical significance was determined by a one-way ANOVA with Tukey’s multiple comparisons test. ns, not significant; **** p < 0.0001.…”

Raw data for Figs 1, 2, 3, 4 and S2. by Areej A. Alfaifi (20422411)

“…Bulk RNA-sequencing of parotid salivary glands from COVID-19 autopsies demonstrated statistically significant decreased expression of histatin and amylase genes. …”

Data Sheet 1_Global, regional, and national burden of pneumococcal disease among children and adolescents aged <20 years from 1990 to 2021: a predictive analysis.docx by Gan-min Wang (21188933)

“…Background<p>Pneumococcal infections remain a leading cause of preventable deaths among children and adolescents aged <20 years. Despite a global decrease in burden, significant regional and socioeconomic disparities, as well as long-term trends, are not fully understood.…”

Image_1_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…D- and L-Glu supplementations showed significant decrease of Glycogenesis (low GYS2/PYGL ratio) and unchanged p-AKT pattern compared to their RD counterparts.…”

Image_1_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…D- and L-Glu supplementations showed significant decrease of Glycogenesis (low GYS2/PYGL ratio) and unchanged p-AKT pattern compared to their RD counterparts.…”

Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…D- and L-Glu supplementations showed significant decrease of Glycogenesis (low GYS2/PYGL ratio) and unchanged p-AKT pattern compared to their RD counterparts.…”

Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…D- and L-Glu supplementations showed significant decrease of Glycogenesis (low GYS2/PYGL ratio) and unchanged p-AKT pattern compared to their RD counterparts.…”

Image 2_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Image 4_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Data Sheet 1_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.zip by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Image 1_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Image 3_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

SEAwise Report on improved predictive models of growth, production and stock quality under different habitat scenarios and incorporating experimental results by Leire Ibaibarriaga (13760979)

“…The third study in the Western Waters analysed relative condition factor in the Bay of Biscay and the Celtic Sea and found significantly decrease over time for 12 species, while two species showed an increase, and three species showed no significant trends. …”

Table 3_Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective.xlsx by Zhen Gong (292434)

“…Additionally, we integrated and analyzed data from two published profiles of latent TB infection, three active TB cases, and two healthy controls.…”