Table 6_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx حسب Jinfeng Liu (32678)

"…Following CX3CR1 knockout in the middle-aged mice, TNF-α and IL-1α levels increased, while CD68, SRA, and RAGE levels decreased in the hippocampus. Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. …"

Table 1_Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.docx حسب Yi-Ting Sun (4691629)

"…</p>Results<p>At 6 months, the median (IQR) VAS score significantly decreased from 66.5 (27) to 24 (34) (95% CI = −38 to −30.5), p < 0.001), and WOMAC scores improved from 29 (22) to 12 (14) (95% CI = −16.5 to −12), p < 0.001). …"

The T-type voltage-gated Ca²⁺ channel Ca_V3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin حسب Haixin Bi (6867632)

"…In mechanism, we demonstrated that PMT inoculation induced cytoplasmic Ca²⁺ inflow, leading to an imbalance of cellular Ca²⁺ homoeostasis and endoplasmic reticulum stress. …"

<i>Hif-1α</i> ablation reduces the efficiency of NeuroD1 gene-based therapy and aggravates the brain damage following ischemic stroke حسب Nashwa Amin (11242159)

"…</p> <p>We found that following stroke, motor dysfunction significantly increased in <i>Hif-1α</i> CKO mice. …"

Data Sheet 1_Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway.pdf حسب Zulipikaer Wusiman (20852138)

"…In addition, we found that GA decreased ROS and MDA levels and increased the expression of GSH, CAT and T-SOD. …"

The quality metrics of 4C-seq data. حسب Tingting Jiang (169999)

"…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"

<i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor حسب Mo-Fei Li (21624535)

"…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …"

Image 1_Yacon root is a functional food beneficial for human health: a meta-analysis of clinical trials.pdf حسب Ling-Hui Pan (9341084)

"…The pooled results showed that YR significantly reduced BMI [SMD = −0.81, 95%CI (−1.54, −0.08)], decreased stool pH [SMD = −1.12, 95%CI (−1.61, −0.62)], softened stools [SMD = 0.94, 95%CI (0.08, 1.80)], facilitated defecation [SMD = 4.03, 95% CI (0.54, 7.52)], improved fiber consumption patterns [SMD = 0.58, 95%CI (0.18, −0.99)]. …"

Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx حسب Mallory A. Perry-Eaddy (20842868)

"…</p>Methods<p>We conducted a post hoc secondary analysis of the MitoPSe clinical study, including N = 119 critically ill children who survived sepsis. …"

Image 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg حسب Bing Gu (276393)

"…In addition, we found that high dose H₂S could improve anxiety and depression-like behavior, mitigate synaptic plasticity deficits, and activate the CREB/BDNF signaling pathway, as well as increase H₂S levels in the hippocampus. …"

CO₂fertilisation counteracts the negative effect of poor water quality on the growth and photosynthesis of a Great Barrier Reef coralline alga_datasheets حسب Bonnie Lewis (20407157)

"…This study examined the individual and interactive impacts of global and local stressors by investigating the effects of increased seawater <i>p</i>CO₂ , elevated nutrient concentrations and reduced light levels on linear growth and metabolic rates of the common branching crustose coralline alga Lithophyllum pygmaeum.</p><p dir="ltr">2. We found complex interactions between factors on algal growth and photosynthetic rates, but overall, growth was significantly enhanced by <i>p</i>CO₂ enrichment under all light and nutrient combinations. …"

Table 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.xlsx حسب Yasufumi Kobayashi (5481530)

"…By contrast, K⁺ accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …"

Table 1_The CD300c antibody CL7 suppresses tumor growth by regulating the tumor microenvironment in non-small cell lung carcinoma.docx حسب Soyoung Kim (117362)

"…We administered CL7 intraperitoneally at doses of 5 or 10 mg/kg twice a week. …"

S2 File - حسب Jinfeng Zhao (142391)

"…We performed a 12-week aerobic exercise intervention in 19-month-old male C57BL/6J mice. …"

Effect of COVID-19 infection on thyroid function status and clinical indexes among hypothyroid outpatients حسب Bingxin Li (1876975)

"…In HT group, thyroid-stimulating hormone (TSH) levels decreased significantly compared to pre-infection levels (<i>p</i> = 0.013), while free triiodothyronine (FT3) levels increased at D90 compared to both D30 post-infection and pre-infection levels (<i>p</i> < 0.001 and <i>p</i> = 0.005). …"

<b>Mystery of Deep Soil Organic Carbon Dynamics Uncovered through Long-term Conservation Tillage Experiments</b> حسب Jianye Li (8914520)

"…We found that <a href="" target="_blank">NT significantly increased active SOC fractions in deep soil, including microbial biomass carbon (MBC, by 104%), particulate organic carbon (POC, by 112%), light fraction organic carbon (LFOC, by 42%) and dissolved organic carbon (DOC, by 22%). …"

In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma حسب Joaquín Yanes-Díaz (20539584)

"…In addition, we measured PI3KCA/AKT/PDK1 gene expression, PI3KCA/AKT/PDK1 protein levels, Epidermal Growth Factor Receptor (EGFR), and angiogenesis in the tumor tissue. …"

Data_Sheet_1_The functions and factors governing fungal communities and diversity in agricultural waters: insights into the ecosystem services aquatic mycobiota provide.pdf حسب Phillip Pham (407350)

"…However, the roles of freshwater fungal communities remain underexplored compared to bacterial communities in this context.</p>Methods<p>We assessed the impact of anthropological and environmental factors on freshwater mycobiota in an agriculturally dominated water basin in eastern Ontario, Canada. …"

<b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b> حسب 昂 轩 (20139579)

"…We also found that SZC-6 significantly reduced MyD88, p-IκBα, and p-P65 protein levels and inhibited the nuclear translocation of P65 in LPS-treated cells. …"

Uncropped western blot images. حسب Tingting Jiang (169999)

"…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"