The Enzyme Effect: Broadening the Horizon of MS Optimization to Nontryptic Digestion in Proteomics حسب Kinga Nagy (603019)

"…We analyzed peptide scores for thousands of peptides and determined optimal collision energy (CE) values. …"

Regioisomeric Engineering for Multicharge and Spin Stabilization in Two-Electron Organic Catholytes حسب H. T. Katie Chung (20496481)

"…Through a systematic study of regioisomers of near-planar aromatic cyclic triindoles and nonplanar nonaromatic cyclic tetraindoles, we demonstrate that this regioisomeric engineering strategy significantly enhances the H-cell cycling stability in the above two new classes of 2e^– catholytes, even when current strategies failed to stabilize the multicharged species. …"

Data Sheet 1_Integrative transcriptome and WGCNA analysis reveal key genes mainly in response to Alternaria alternata in Populus simonii × P. nigra.docx حسب Siyuan Liu (696701)

"…Whereas ABA content continued to increase until the fifth day and CAT content decreased and then increased. We subsequently identified 14,997 differentially expressed genes (DEGs) among the transcriptomic sequences(|log2FoldChange| > 1 and FDR value < 0.05), with genes encoding members of the ERF, MYB, bZIP, and WRKY transcription factor families being differentially expressed. …"

Table 1_Integrative transcriptome and WGCNA analysis reveal key genes mainly in response to Alternaria alternata in Populus simonii × P. nigra.xlsx حسب Siyuan Liu (696701)

"…Whereas ABA content continued to increase until the fifth day and CAT content decreased and then increased. We subsequently identified 14,997 differentially expressed genes (DEGs) among the transcriptomic sequences(|log2FoldChange| > 1 and FDR value < 0.05), with genes encoding members of the ERF, MYB, bZIP, and WRKY transcription factor families being differentially expressed. …"

Supplementary file 1_Dynamic reconfiguration and transition of whole-brain networks in patients with MELAS revealed by a hidden Markov model.docx حسب Qingyun Yu (18837625)

"…Based on HMM, fractional occupancies in states 5 and 6 for MELAS were significantly decreased (p < 0.001), but fractional occupancies in states 2, 3, 4, 7, 8, 9, 10, and 11 were significantly increased (p < 0.05), compared to HCs. …"

Data Sheet 1_Global respiratory tumor mortality correlation study with economic level, 2000–2019.docx حسب Mingjie Wang (1719895)

"…</p>Results<p>The core cohort included 50 countries with sufficient data. The global mean ASMR for respiratory cancers showed a decreasing trend from 2000 to 2019. …"

Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif حسب Kun-Lin Lu (7256960)

"…All pemphigus patients demonstrated improved antibody responses after the third vaccination and none of them suffered from severe COVID-19 illness. Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…"

Image 2_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif حسب Kun-Lin Lu (7256960)

"…All pemphigus patients demonstrated improved antibody responses after the third vaccination and none of them suffered from severe COVID-19 illness. Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…"

Data Sheet 5_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease حسب Akanksha Chhabra (71080)

"…Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). …"

Image1_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.jpeg حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Table 1_Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation.docx حسب Weilong Li (8778146)

"…Importantly, the loss of Claudin-2 significantly decreased the deposition of the C5b-9 complex, commonly referred to as the membrane attack complex (MAC), whereas the overexpression of Claudin-2 enhanced the deposition of the C5b-9 complex, indicating that Claudin-2 facilitates complement activation. …"

Data Sheet 2_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

Image 1_Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice.pdf حسب Yan Gong (103494)

"…Additionally, MA notably inhibited osteoclast activity, as evidenced by a decrease in the number of osteoclasts and a significant suppression of F-actin formation. …"

Image3_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg حسب Elena Chiappini (304802)

"…Our data confirm the variability in the definition, work-up, and management of FUO. We observed that in children with FUO paracetamol was significantly less commonly preferred than in non-prolonged fever, which is not supported by evidence. …"

Image 4_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.tif حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

Table3_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.xlsx حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Canopy effects from biomass utilization on the Priest River Experimental Forest حسب Ina S. Miller (19658593)

"…Our BRDI research goals, targeted the soil and water component of the area where the biomass was removed once reduction had taken place These goals examined whether biomass reduction/removal indicated a significant increase in soil erosion, decrease in infiltration or otherwise adversely impact water resources, compared to control sites. …"

Image 3_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.tif حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

Data Sheet 1_Global burden and trends of occupational noise-induced hearing loss (1990–2021) and projection to 2040.pdf حسب Xin Gong (592328)

"…By 2040, ONIHL DALYs are predicted to increase, whereas the ASDR is projected to decrease; however, the disease burden among females will rise significantly.…"