Data Sheet 3_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf by Tianmin Huang (20561477)

“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”

Image2_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.tif by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Data Sheet 2_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf by Tianmin Huang (20561477)

“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”

Table1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Data Sheet 1_Acute-phase proteins as biomarkers of inflammation in HIV patients with latent tuberculosis: a prospective study.pdf by Nathella Pavan Kumar (8911094)

“…Following six months of INH prophylaxis, significant reductions in these markers were observed in both groups, suggesting a reduction in inflammation.…”

Table3_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Supplementary Material for: Placebo effect of verbal instructions coupled with pharmacological treatment: results from a randomized controlled trial in migraine patients by figshare admin karger (2628495)

“…Since the first group had a decrease across timepoints of the score while the second group had a peak at T2, difference between them was statistically significant (p = 0.029; η2 = 0.049). …”

White-to-opaque switching frequencies of single TF heterozygotes in a <i>WOR1</i>(KR-to-G) strain background. by Collin Ganser (8924843)

“…Colored bars indicate significant differences from the WT control; blue for decreased switching and red for increased switching. …”

Table 1_Efficacy of thymosin α1 for sepsis: a systematic review and meta-analysis of randomized controlled trials.docx by Bin Gu (223694)

“…The comprehensive meta-analysis demonstrated a significant reduction in 28-day mortality associated with Tα1 administration (OR 0.73, 95%CI: 0.59-0.90, P = 0.003). …”

Figure 5 from Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection by Peter J. Mazzone (20018668)

“…Population-level modeling demonstrates significant health benefits when a blood-based test is available as an alternative for lung cancer screening.…”

Table 1_The impact of telework on absenteeism, presenteeism, and return to work among workers with health conditions: a scoping review.docx by Julien Ducas (20501079)

“…In contrast, findings on presenteeism are conflicting: some studies report that telework increases the likelihood of working while sick, others suggest a decrease, and some report no significant impact or conflicting results. …”

Table 2_The impact of telework on absenteeism, presenteeism, and return to work among workers with health conditions: a scoping review.docx by Julien Ducas (20501079)

“…In contrast, findings on presenteeism are conflicting: some studies report that telework increases the likelihood of working while sick, others suggest a decrease, and some report no significant impact or conflicting results. …”

Table1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.XLSX by Zhen Kang (335450)

“…In the MVMR result, only AFB (OR = 0.804, 95% CI 0.661–0.978; p = 0.029) retained a direct causative relationship with PPD.</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. …”

Microemulsion for stimulating wells with high gas and water cut by Baghir A. Suleimanov (20460195)

“…It has been found that the treatment of the bottomhole zone with the developed microemulsion leads to a significant reduction in the size of gas bubbles due to a decrease in interfacial tension, which facilitates their removal from the bottomhole zone and increases hydraulic diffusivity of the porous medium for oil approximately five times. …”

Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Video 3_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Video 1_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Minimal data set. by Daan P. van den Brink (9900073)

“…This effect might be attributed to decreased resuscitation volumes rather than the type of fluid.…”

Various stereological parameters characterizing lung parenchyma and AEII before, during and after alveolarization as well as in adults. by Julia Hüttmann (22656283)

“…PLoS One. 2024 Mar 14;19(3):e029. b) The total number of alveolar epithelial cells type II (N(AEII, lung)) shows a significant increase after the end of bulk alveolarization and in adults compared to 3 days old rats. c) During alveolarization the number of AEII per mm² alveolar surface (N(AEII, lung)/S(alveoli, lung)) decreases continuously reaching the significant lowest values in adults. d) The number of AEII related to lung volume decreases continuously during alveolarization. …”

Figure 4 from OATP1B-type Transport Function Is a Determinant of Aromatase Inhibitor–Associated Arthralgia Susceptibility by Hanieh Taheri (20944284)

“…<p>OATP1B deficiency results in elevated AI plasma exposure and decreased liver accumulation. <b>A,</b> Pharmacokinetic profile of letrozole after a single oral dose of 10 mg/kg in wild-type and Oatp1a/1b^(−/−) mice. …”