Mitigation of Senescence Burden in Doxorubicin-Induced Senescent Endothelial Cells by MitoQ Treatment Through Diminishing Mitochondrial ROS and DNA Damage. by Hossein Abdeahad (22177792)

“…This study investigates whether co-treatment with MitoQ, a mitochondria-targeted antioxidant, attenuates DOXO-induced endothelial damage. …”

Data Sheet 1_Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models.docx by Yufeng Huang (782683)

“…At the same time, the levels of these PGs decreased significantly (p < 0.01 vs. LPS-induced group) after the positive drug (dexamethasone) intervention. …”

Strategy parameters across development for male mice in set size = 2 and set size = 4 from winning computational model. by Juliana Chase (20469427)

“…RL parameter <i>α</i>₊ learning rate and decision noise parameter softmax <i>β</i> were stable across development in both set size = 2 (A-B) and set size = 4 (F-G). Both parameters S1 “Inappropriate Lose-Shift” and S3 “Inappropriate Lose-Stay” decreased significantly with age in set size = 2 (C: <i>p</i> = 0.02, E: <i>p</i> = 0.04), but not in set size = 4 (H,J). …”

Table 1_Guiren Runchang granules alleviate slow transit constipation in mice by modulating gut microbiota and short-chain fatty acids.docx by Xinfeng Bai (5049932)

“…Specifically, the relative abundance of the genera Alloprevotella and Muribaculum increased, while that of Prevotellaceae_NK3B31_group, Ruminococcus, and Lachnospiraceae_UCG-001 decreased. These microbiota changes were significantly correlated with SCFAs level, motility-related hormone concentrations, and defecation phenotype. …”

Supplementary Material for: Atypical COVID-19-related Acute Macular Neuroretinopathy with Progression resulting in Severe Vision Loss by Weinberger E.M (20394746)

“…Introduction: We review the clinical course of a patient with decreased vision in the setting of COVID-19 infection consistent with an atypical presentation of acute macular neuroretinopathy (AMN). …”

Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx by Zeli Zhang (3422570)

“…Furthermore, both QWBZP decoction and QWBZP-TG decreased the levels of DAO, D-Lactate, sIgA, IL-6, and TNF-α in the AAD mice. …”

Source data.zip by Xiaoyan Pan (21158717)

“…In vivo, melatonin significantly increased MT1R (melatonin receptor 1A) expression in BPA-treated mouse testicular cells and the content of catalase, superoxide dismutase 2, and glutathione, while decreasing the level of malondialdehyde. …”

Data Sheet 1_Machine learning assisted breathomic approach for early-stage thoracic cancer detection.docx by Zhenguang Chen (518931)

“…Additionally, in a cohort of 58 cancer patients, model-predicted risk significantly decreased post-surgery (p < 0.01), indicating a strong correlation with disease burden reduction.…”

Boron-doped diamond MOSFETs operating at temperatures up to 400°C by Jiangwei Liu (2524750)

“…Conversely, the on-resistance decreases significantly from 1469.8 kΩ mm to 16.5 kΩ mm. …”

Data Sheet 1_Perilipin 5 alleviates ferroptosis of cardiomyocytes by targeting USP10-p53-TfR proteasome-dependent degradation.docx by Jianqiao Zhao (14519036)

“…Introduction<p>Perilipin 5 (PLIN5) is a key protein attached to lipid droplets that plays a critical role in cellular lipid metabolism. …”

C2f and BC2f module structure diagrams. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

YOLOv8n detection results diagram. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

YOLOv8n-BWG model structure diagram. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Image 2_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif by Viana Q. Pham (22081163)

“…In this study, we show that fenestrated capillaries in the median eminence (ME) and area postrema (AP)—two distinct circumventricular organs critical for metabolic control—undergo differential remodeling when exposed to circulating monosodium glutamate (MSG), a BBB-impermeable neurotoxin. Upon MSG exposure, fenestrated capillaries and vascular permeability were decreased in the ME but increased in the AP, and these changes were closely associated with the expression of angiogenic factors pleiotrophin (Ptn) and vascular endothelial growth factor A (Vegfa). …”

Table 2_Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling.xlsx by Lulu Tang (2664904)

“…Furthermore, a medium dosage of GDL treatment significantly rebalance microbiota composition and function and modulated lipid and lipid-like molecule levels.…”

data.zip by Zhizhang Dong (21158474)

“…Compared with the control group, the thickness of retina in the experimental group was significantly reduced (t=5, P=0.0075), the number of retinal pigment epithelium was statistically decreased (t=4.243, P=0.0132), and the pyrolytic related proteins NLRP3, Caspase-1, GSDMD, IL-1β and IL-18 were strongly red positive in retinal pigment epithelium (P<0.05). …”

BiFormer structure diagram. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

DataSheet1_Case report: Comprehensive clinical, pathological and genetic investigations to decipher the background of cyclic thrombocytopenia.pdf by Zsófia Flóra Nagy (19758660)

“…Whole exome sequencing revealed a heterozygous missense variant of uncertain significance in the SERPINC1 gene, which has been associated with hereditary antithrombin deficiency. …”