Image 1_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Image 8_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Image 5_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Table 1_Magnesium application partially reversed the negative effects of mulching on rhizosphere nitrogen cycling in a Phyllostachys praecox forest.xlsx by Hong Zhao (325)

“…To address this, our study investigated rhizosphere nitrogen cycling in Lei-bamboo across a short-term degradation cycle. We found that mulching enhanced the abundance of 16S-rRNA and nitrogen-cycling functional genes. …”

Image 3_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Image 9_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Supplementary file 1_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.</p>Results<p>We found a significant separation along the coordinate axis between people with normal and declined cognition by principal component analysis, as confirmed by the Manover-Wilk test. …”

Supplementary file 4_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.</p>Results<p>We found a significant separation along the coordinate axis between people with normal and declined cognition by principal component analysis, as confirmed by the Manover-Wilk test. …”

Supplementary file 5_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.</p>Results<p>We found a significant separation along the coordinate axis between people with normal and declined cognition by principal component analysis, as confirmed by the Manover-Wilk test. …”

Supplementary file 3_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.</p>Results<p>We found a significant separation along the coordinate axis between people with normal and declined cognition by principal component analysis, as confirmed by the Manover-Wilk test. …”

Supplementary file 2_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.</p>Results<p>We found a significant separation along the coordinate axis between people with normal and declined cognition by principal component analysis, as confirmed by the Manover-Wilk test. …”

Related to Fig 4. <i>NDUFS7</i> depletion in neurons lowers the failure rate of neurotransmission at very low calcium concentrations. by Bhagaban Mallik (12459375)

“…<i>p</i>-values are indicated in the figure, ns; they are not significant. Statistical analysis based on Student's <i>t</i> test. …”

Table 1_Effect of simulated acidification on soil properties and plant nutrient uptake of eggplant in greenhouse.docx by Tianqi Wang (4093009)

“…Among the available nutrients, only potassium levels did not exhibit significant variation across treatments. However, the levels of macro elements in the soil consistently decreased, while the concentrations of trace elements (Fe, Cu, Zn) increased with rising acidity; conversely, the levels of other trace elements (B, Mo, Mn) decreased. …”

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... by Jing Lu (120666)

“…However, there is still a knowledge gap regarding the relationship between SI and mortality in the CVD population.…”

raw data by Boya Gao (21686150)

“…Bacterial abundance under moderate and extreme disturbances was significantly lower than that in the control, whereas fungal abundance was significantly higher under extreme disturbance. …”

Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…This suggests an underutilisation of available treatments, highlighting a gap in the management of high CV risk patients.</p>…”

Data Sheet 1_A comparative analysis of nutritional content changes in six Chinese cuisines prepared using industrial versus traditional hand-cooked modes.docx by Xuan Wang (55634)

“…An inter-group t-test indicated no significant differences in nutrient content changes between the two cooking modes (p > 0.05), except for vitamin B6 retention, which was significantly lower in traditional hand-cooked modes compared to industrial modes (p < 0.05).…”

Table 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.docx by Zehao Jin (11408687)

“…In addition, temporal trend analysis was conducted using joinpoint regression to identify significant inflection points and calculate the annual percent change (APC) estimates. …”

Data Sheet 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.csv by Zehao Jin (11408687)

“…In addition, temporal trend analysis was conducted using joinpoint regression to identify significant inflection points and calculate the annual percent change (APC) estimates. …”

S1_Figure.pdf by George Brooks (21579206)

“…We observed no age-associated changes in coupling efficiency (ADP:O) of mitochondrial reticulum preparations, but respiratory control (RCR) was decreased in older mice. …”