<b>Astragalus polysaccharide and </b><b><i>Clostridium butyricum</i></b><b> synergistically inhibit bone loss in mice with humanized intestinal flora</b> by Hongtao Zhang (20774453)

“…We used a humanized intestinal flora mouse model and showed that APS-CB significantly inhibited bone loss caused by simulated weightlessness. …”

Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…In addition, we found that high dose H₂S could improve anxiety and depression-like behavior, mitigate synaptic plasticity deficits, and activate the CREB/BDNF signaling pathway, as well as increase H₂S levels in the hippocampus. …”

Data Sheet 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.pdf by Yasufumi Kobayashi (5481530)

“…By contrast, K⁺ accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”

Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…In addition, we found that high dose H₂S could improve anxiety and depression-like behavior, mitigate synaptic plasticity deficits, and activate the CREB/BDNF signaling pathway, as well as increase H₂S levels in the hippocampus. …”

Data Sheet 1_Land use change has profoundly altered the process of bacterial community assembly in the northeastern black soil zone.pdf by Ning Sun (162468)

“…Co-occurrence network analysis showed that reclamation reduced interspecies interactions and significantly decreased network complexity, connectivity, and cohesion (P < 0.05). …”

Data Sheet 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.xlsx by Bing Gu (276393)

“…In addition, we found that high dose H₂S could improve anxiety and depression-like behavior, mitigate synaptic plasticity deficits, and activate the CREB/BDNF signaling pathway, as well as increase H₂S levels in the hippocampus. …”

Data Sheet 1_Efficacy and safety of shensong yangxin capsules for persistent atrial fibrillation: a Systematic Review and meta-analysis of randomized controlled trials.docx by Yifan Chen (446592)

“…We assessed methodological quality with the Cochrane Risk of Bias Tool 2.0, and conducted meta-analyses with RevMan 5.4.…”

Cytochrome bd-II oxidase CyxA promotes the pathogenicity of <i>Klebsiella pneumoniae</i> by resisting oxidative stress by Xiao Xiao (99147)

“…Additionally, the expression levels of <i>cyxA</i> at 37°C and 41°C were significantly higher compared to 30°C, and the Δ<i>cyxA</i> strain exhibited significantly lower viable counts, elevated intracellular reactive oxygen species (ROS) levels, and decreased total antioxidant capacity (T-AOC) relative to WT at 37°C and 41°C. …”

Image 1_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Table 1_Artificial grassland establishment alters soil organic carbon fractions and cbbL-type carbon-sequestering microbial communities.xlsx by Linge Shan (22805624)

“…Compared to CK, both grassland types increased the relative abundance of Actinobacteria but decreased that of Planctomycetes. At the genus level, LG significantly enriched SinoRhizobium and MesoRhizobium, whereas GG promoted Microvirga and Bradyrhizobium.…”

Data Sheet 1_Hybridization promotes growth performance by altering rumen microbiota and metabolites in sheep.docx by Rui Zhang (13940)

“…Acetate, propionate, and total volatile fatty acid (VFA) concentrations in the DH group were higher than those in the HH group, whereas NH₃-N concentration decreased in the DH and SH groups. Metagenomic analysis revealed that several Prevotella and Fibrobacter species were significantly more abundant in the DH group, contributing to an increased ability to degrade dietary cellulose and enrich their functions in enzymes involved in carbohydrate breakdown. …”

Data Sheet 1_Artificial grassland establishment alters soil organic carbon fractions and cbbL-type carbon-sequestering microbial communities.xlsx by Linge Shan (22805624)

“…Compared to CK, both grassland types increased the relative abundance of Actinobacteria but decreased that of Planctomycetes. At the genus level, LG significantly enriched SinoRhizobium and MesoRhizobium, whereas GG promoted Microvirga and Bradyrhizobium.…”

Table 1_Evaluation of degree centrality and neurological outcomes in patients with herpes simplex encephalitis.docx by Dongzhi Liu (2747134)

“…We also found that DC changes in the right thalamus (r = 0.241, p = 0.044), the left insula (r = 0.254, p = 0.034), and the left lingual gyrus (r = 0.275, p = 0.021) were significantly associated with higher GCS scores. …”

Data Sheet 2_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xlsx by Wenyong Liao (21669332)

“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”

Presentation 1_CD26 as a potential therapeutic target for lung adenocarcinoma.pptx by Wolfgang Jungraithmayr (335920)

“…Introduction<p>CD26/dipeptidyl peptidase 4 (CD26, DPP4) is a transmembrane exopeptidase that modulates tumorigenesis in different malignancies. We demonstrated before that CD26 inhibition decreases lung tumor growth in experimental models. …”

Table 1_CD26 as a potential therapeutic target for lung adenocarcinoma.docx by Wolfgang Jungraithmayr (335920)

“…Introduction<p>CD26/dipeptidyl peptidase 4 (CD26, DPP4) is a transmembrane exopeptidase that modulates tumorigenesis in different malignancies. We demonstrated before that CD26 inhibition decreases lung tumor growth in experimental models. …”

Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls by Wenyong Liao (21669332)

“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”

Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff by Yulia Dwi Setia (21590591)

“…Introduction<p>Eimeria pragensis, an intestinal protozoa infecting mice, induces colitis and reduces goblet cell numbers in the large intestine. In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.…”