Docetaxel and quercetin-loaded lipid nanocarrier optimized by quality by design for glioblastoma therapy: a ligand-conjugated and therapeutic repurposing approach by Zufika Qamar (22259678)

“…Compared to non-conjugated NLC and (DTX-QUR) suspension (SUS), Tf-(DTX-QUR) NLC showed 3.6- and 5.8-fold decrease in IC₅₀, respectively. Cellular uptake studies demonstrated significantly (<i>***p < 0.001</i>) high internalization of Tf-conjugated NLC to U87-MG cells. …”

Table1_Identification and expression profiling of neuropeptides and neuropeptide receptor genes in a natural enemy, Coccinella septempunctata.DOCX by ShunDa Han (19822464)

“…During diapause induction, the mRNA abundance of AKH was notably higher on the 10th day compared to non-diapause females, but decreased by the 20th day. In contrast, GPHA showed lower expression levels on the 5th day of diapause induction compared to non-diapause females, but increased significantly by the 15th and 20th days. …”

White-to-opaque switching frequencies of double TF heterozygotes in a <i>WOR1</i>(KR-to-G) strain background. by Collin Ganser (8924843)

“…<p><b>(A)</b> Genotypes of the strains used in <b>B + C</b>. …”

Table 2_Quantitative evaluation of IVL: based on the tunica media gypsum calcification model and a prospective animal study.doc by Zongwei Liu (3133743)

Table 1_Quantitative evaluation of IVL: based on the tunica media gypsum calcification model and a prospective animal study.doc by Zongwei Liu (3133743)

Supplementary file 1_Indirect regeneration of long-term callus cultures in gladiolus: a protocol for stable genetic fidelity.docx by Seyedehraziyeh Mousavimatin (21398525)

“…This medium led to an 80% decrease in the accumulation of phenolic compounds across all cultivars in comparison to the control. …”

Image_1_The causal effects of dietary component intake and blood metabolites on risk of delirium: a Mendelian randomization study.pdf by Qian Zhu (191342)

Table_1_The causal effects of dietary component intake and blood metabolites on risk of delirium: a Mendelian randomization study.xlsx by Qian Zhu (191342)

Analysis of biases in amplicon coverage across samples sequenced with diverse Ampliseq-based protocols (DDD/IDI/III – corresponds to variations of PCR mix1 (I/D), ligase/buffer (I/... by P.A. Shatalov (21485215)

“…<p><b>(A)</b> – heatmap of amplicon coverage (% of average coverage) across samples demonstrates significant variation in per-sample set of dropped out (10% of average sample coverage) amplicons depending on <b>i)</b> PCR mix 2 used <b>ii)</b> Digest Mix used. …”

Data Sheet 1_The efficacy and safety of panax quinquefolius saponin for heart failure: a systematic review and meta-analysis.pdf by Jing Wang (6206297)

“…</p>Results<p>This study included nine RCTs involving a total of 952 patients with HF. The results of a meta-analysis under a random-effects model showed that adjuvant PQS therapy significantly increased LVEF (MD = 6.23, 95% CI [4.35, 8.12], P < 0.00001), 6MWTD (MD = 25.26, 95% CI [8.23, 42.30], P = 0.004), and decreased BNP/NT-pro-BNP (MD = −187.94, 95% CI [−267.20, −108.67], P < 0.00001), LVEDV (MD = −22.83, 95% CI [−42.79, −2.87], P = 0.02), LVEDD (MD = −4.76, 95% CI [−5.77, −3.74], P < 0.00001), and LVESV (MD = −11.86, 95% CI [−19.89, −3.83], P = 0.004) in patients with HF.…”

Burden trends and risk factors for prostate cancer from 1990 to 2021: a systematic analysis of the Global Burden of Disease Study 2021 by Yuan Xu (161775)

“…PCa was more common in regions with a high SDI. Mortality was the highest in regions with a low SDI. …”

Image 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.pdf by Zhanyi Yang (5142182)

“…Furthermore, MORC4 knockdown led to an increased expression of genes associated with cholesterol synthesis (HMGCR), varying levels of genes implicated in the uptake of fatty acids and cholesterol (PCSK9, PLTP, CD36), and a decrease in the levels of genes involved in triglyceride hydrolysis (APOC2, APOA4, LIPG, LIPA). …”

Table 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.xlsx by Zhanyi Yang (5142182)

“…Furthermore, MORC4 knockdown led to an increased expression of genes associated with cholesterol synthesis (HMGCR), varying levels of genes implicated in the uptake of fatty acids and cholesterol (PCSK9, PLTP, CD36), and a decrease in the levels of genes involved in triglyceride hydrolysis (APOC2, APOA4, LIPG, LIPA). …”

Relationship between purposeful rumination and post-traumatic growth of college students who experienced childhood trauma: a regulated intermediary model by Sanglin Zhao (20599835)

“…Results: Correlation analysis showed that purposive rumination, positive coping and post-traumatic growth were significantly correlated. Regression analysis showed that purposive rumination had a significant direct effect on post-traumatic growth (β=0.148, P<0.001) . …”

Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx by Vanessa I. T. Zwaans (22163257)

“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”

Supplementary file 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.pd... by Bei Li (90587)

“…Joinpoint regression analysis revealed the greatest decline in ASYR occurred in 2003–2008, while the most significant decrease in ASDR occurred in 1994–1999. …”

Ambulatory modeling of vocal hyperfunction (Parra et al., 2025) by Jesús A. Parra (20677929)

“…Higher DPI values, reflecting more severe PVH, were associated with increased mean LCA activation and decreased LCA variability, along with decreased mean CT activation and increased median PS. …”

Conservation in a changing world: assessing the conservation status of an agruculturally adapted species, the Blue Crane. Chapter 2: Population Trends by Christie Craig (21008186)

“…Continued CAR counts will be important to ascertain whether the population has stabilised at a lower density or is continuing to decrease. In winter, Blue Cranes select for pastures (especially lucerne and lupin fields) in the Karoo and Western Cape wheatlands. …”

Image 2_Plasma fibrinogen level and acute aortic dissection prognosis—insights from a two-center cohort study.pdf by Jiaxin Xiao (4423546)

“…After multivariate adjustment, each 1 g/L increase in PFL was associated with a 18.9% decrease in 30-day mortality rate and a 11.5% decrease in long-term mortality rate (P < 0.001). …”

Table 1_Plasma fibrinogen level and acute aortic dissection prognosis—insights from a two-center cohort study.pdf by Jiaxin Xiao (4423546)

“…After multivariate adjustment, each 1 g/L increase in PFL was associated with a 18.9% decrease in 30-day mortality rate and a 11.5% decrease in long-term mortality rate (P < 0.001). …”