Cell-targeted transgenic control of 5HT_2AR levels in neurons and glia during the experience-dependent critical period. حسب Vanessa Kay Miller (19775496)

"…Two-way ANOVA with Tukey’s multiple comparison shows EB experience-dependent increase in 5HT_2A receptor levels in both transgenic controls (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 5.38 × 10⁻¹⁰, <i>elav</i>-Gal4; <i>p</i> = 0.0205), a significant decrease in 5HT_2A receptor levels in both RNAi conditions (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 4.63 × 10⁻¹⁰, <i>elav-</i>Gal4; <i>p</i> = 1.05 × 10⁻⁹), and a significant elevated EB response with glial <i>5HT</i>_<i>2A</i><i>R</i> OE (<i>n</i> = 10/condition, <i>p</i> = 2.36 × 10⁻⁹). …"

PARP9 knockdown promotes apoptosis and DNA damage. حسب Yating Li (1819822)

"…<p>(A) Gene Set Enrichment Analysis (GSEA) was conducted to identify the major enriched pathways of differentially expressed genes following PARP9 downregulation. …"

The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... حسب Mohammed A. Altowijri (22461945)

"…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …"

DataSheet1_Efficacy of combination therapy of vitamin D and bisphosphonates in the treatment of postmenopausal osteoporosis: a systematic review and meta-analysis.zip حسب Yuangui Yang (6746633)

"…However, the combination of VitD and bisphosphonates did not show a significant advantage over monotherapy in terms of improving osteocalcin levels. …"

Impact of COVID-19 on early intervention referrals (Zellner et al., 2025) حسب Matthew A. Zellner (12043395)

"…</p><p dir="ltr">Zellner, M. A., Kaat, A. J., & Roberts, M. Y. (2025). The impact of COVID-19 on early intervention referrals and enrollments: An interrupted time series analysis. …"

Supplementary file 1_Evaluation of drug interactions in outpatients taking antipsychotic medications.docx حسب Bshra A. Alsfouk (13259895)

"…The most frequent potential adverse effects were increased sedation (36%), hyperglycemia (15%) and decreased blood pressure (14%). Receiving polypharmacy (i.e., ≥5 drugs concomitantly administered) was significantly associated with an increased probability of drug interaction occurrence (OR = 42, P = 0.0026). …"

Table 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.xlsx حسب Sergey A. Gorbarenko (13696381)

"…The Holocene Thermal Maximum (HTM) happened between HCCEs 5 and 4a and was interrupted by HCCE 4c and 4b, coeval, with a significant southward shift of the ITCZ, likely related to cooling in the tropical zone. …"

Data Sheet 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.docx حسب Sergey A. Gorbarenko (13696381)

"…The Holocene Thermal Maximum (HTM) happened between HCCEs 5 and 4a and was interrupted by HCCE 4c and 4b, coeval, with a significant southward shift of the ITCZ, likely related to cooling in the tropical zone. …"

Table_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.DOCX حسب Meng Chen (48769)

"…In the reverse MR study, weight median analysis showed that NAFLD caused a decrease in ALM (OR = 0.953, 95%CI 0.957–0.994, p = 0.001); whereas NAFLD showed no correlation with usual walking pace or grip strength (all with p > 0.05). …"

Effect of the strategy game Mangala on cognitive function, anxiety, depression, and fine motor skills in individuals with Alzheimer’s disease: A randomized controlled trial حسب Aziz Dengiz (20494793)

"…<p>Cognitive impairment, changes in mood, and decrease in fine motor skills are some of the most common symptoms experienced by individuals with Alzheimer’s Disease (AD). …"

Table 2_Integrated effects of Kampo treatment on gastrointestinal symptoms and stress in patients with functional dyspepsia: a preliminary prospective observational study.docx حسب Lian Liang (11550511)

"…Additionally, there was a significant decrease in negative mood components (anger and depression) and total mood disturbance. …"

Table 1_Integrated effects of Kampo treatment on gastrointestinal symptoms and stress in patients with functional dyspepsia: a preliminary prospective observational study.xlsx حسب Lian Liang (11550511)

"…Additionally, there was a significant decrease in negative mood components (anger and depression) and total mood disturbance. …"

Table 1_Efficacy and safety of live combined Bacillus subtilis and Enterococcus faecium in patients with constipation: a meta-analysis of randomized controlled trials.docx حسب Wenwen Li (735004)

"…The defecation difficulty score tended to decrease in the experimental group relative to that in the control group, although this did not reach statistical significance [SMD (95% CI) = −1.924 (−3.947 to 0.099); p = 0.062]. …"

Image 1_Efficacy and safety of live combined Bacillus subtilis and Enterococcus faecium in patients with constipation: a meta-analysis of randomized controlled trials.tif حسب Wenwen Li (735004)

"…The defecation difficulty score tended to decrease in the experimental group relative to that in the control group, although this did not reach statistical significance [SMD (95% CI) = −1.924 (−3.947 to 0.099); p = 0.062]. …"

Data Sheet 1_Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qual... حسب Shukri A. Hassan (14245301)

"…Participants viewed LA ART as a welcome alternative to oral ART due to benefits like improved adherence, reduced pill burden, increased convenience, enhanced privacy, decreased stigma, lower risk of accidental disclosure, and convergence in using LA contraception. …"

Data Sheet 2_Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qual... حسب Shukri A. Hassan (14245301)

"…Participants viewed LA ART as a welcome alternative to oral ART due to benefits like improved adherence, reduced pill burden, increased convenience, enhanced privacy, decreased stigma, lower risk of accidental disclosure, and convergence in using LA contraception. …"

Correlation analyses between studied genes. حسب Marwa A. Ali (11973086)

"…<div><p>Background</p><p>The SARS-CoV-2 virus’s frequent mutations have made disease control with vaccines and antiviral drugs difficult; as a result, there is a need for more effective coronavirus drugs. …"

Primers used in q-PCR. حسب Marwa A. Ali (11973086)

"…<div><p>Background</p><p>The SARS-CoV-2 virus’s frequent mutations have made disease control with vaccines and antiviral drugs difficult; as a result, there is a need for more effective coronavirus drugs. …"

Data Sheet 1_Impact of meteorological factors on influenza incidence in Wuxi from 2014 to 2019: a time series and comprehensive analysis.docx حسب Menglan He (3768739)

"…No significant gender differences were observed. The impacts of air pressure, temperature, precipitation, and sunshine duration on children aged 3–14 were greater than on other age groups. …"

Effect of regional nerve block on tourniquet-related injury in pediatric patients undergoing lower limb surgery: a randomized controlled study حسب Qin Xia (1758646)

"…Additionally, patients in the PNB group had a significantly shorter time to first ambulation and a shorter hospital length of stay.…"