Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif by Yang Jing (2231179)

“…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …”

Table 2_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…Finally, qRT-PCR confirmed the differential expression of key genes in clinical samples.</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Chromatin accessibility profiling of Treg cells in acute urticaria by Leilei Wen (3551444)

“…However, the role of Tregs in the pathogenesis of acute urticaria is unclear. In this study, we found that the frequency of Tregs in peripheral blood mononuclear cells (PBMCs) was decreased in patients with acute urticaria compared with normal controls by flow cytometry. …”

Data Sheet 1_Spatial and temporal variability in blue carbon accumulation in the largest salt marsh in British Columbia, Canada.docx by Karen E. Kohfeld (11936879)

“…Historical aerial photographs indicate that the eastern marsh area (BBE, MB) decreased by ~35% while BBW expanded by ~20% since 1930. …”

The Type I JAKinib, ruxolitinib, promotes pJAK1 and pJAK2 phosphorylation in MSCs from salivary glands. by Ilya Gurevic (1326786)

“…At each time or dose of ruxolitinib, we harvested cells for protein and performed western blot for the indicated target. …”

Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif by Jing Wang (6206297)

“…Finally, to investigate the expression and function of ACTR6 in liver cancer cells, real-time qPCR (RT-qPCR) assays, CCK-8, clone creation, cell cycle, and transwell migration and invasion experiments were carried out.</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”

DataSheet1_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.docx by Weina Xu (558990)

“…Additionally, immune infiltration, tumor mutational load (TMB), and drug sensitivity were evaluated. We validated the expression levels of prognostic genes. …”

Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg by Ling Hu (374570)

“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip by Erli Wu (17785482)

“…However, its precise role and underlying mechanisms in periodontitis (PD) remain unclear.</p>Methods<p>We analyzed single-cell RNA sequencing (scRNA-seq) on gingival tissues from PD patients and healthy individuals to profile cellular composition and quantify cell-type distributions. …”

Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…Finally, qRT-PCR confirmed the differential expression of key genes in clinical samples.</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx by Jing Wang (6206297)

“…Finally, to investigate the expression and function of ACTR6 in liver cancer cells, real-time qPCR (RT-qPCR) assays, CCK-8, clone creation, cell cycle, and transwell migration and invasion experiments were carried out.</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”

Supplementary data.xlsx by Danjun Li (21443051)

“…Sirt6 is a NAD+-dependent epigenetic regulator that has recently been found to play an important role in maintaining telomere stability. Here, we report for the first time that NAD+ levels are significantly lower in blastocysts cultured in vitro than that in blastocysts developed in vivo, leading to impaired Sirt6 function, further triggering telomere shortening of the inner cell mass and possibly affecting newborn offspring. …”

Source data.xlsx by Qian Cheng (20991434)

“…This limitation restricts electrode thickness, decreases power density, and shortens battery lifetime. …”

Differential neural dynamics in the GNP model incorporating electrodiffusion and ion concentration changes. by Zichao Liu (4591993)

“…(f) The harmonic means of intramembrane potassium and chloride concentrations increase, whereas for sodium, it decreases during neural activity. …”

Physicochemical property and archaea community characteristics in casing soil of cultivating Stropharia rugosoannulata by Songhao Tian (22609826)

“…The results showed that sucrase activity decreased significantly and then increased with the increase of cultivation time, and urease activity fluctuated and then decreased significantly. …”

Data_Sheet_1_Long-term sheep grazing reduces fungal necromass carbon contribution to soil organic carbon in the desert steppe.pdf by Tianqi Zhao (1305615)

“…Our findings indicate that MNC decreased under moderate and heavy grazing, while light grazing did not significantly differ from no grazing. …”

Strategy parameters across development for male mice in set size = 2 and set size = 4 from winning computational model. by Juliana Chase (20469427)

“…Both parameters S1 “Inappropriate Lose-Shift” and S3 “Inappropriate Lose-Stay” decreased significantly with age in set size = 2 (C: <i>p</i> = 0.02, E: <i>p</i> = 0.04), but not in set size = 4 (H,J). …”

Anthropogenic soil acidification severely imperils microbial diversity and functionality: A global synthesis by d xz (16960341)

“…Anthropogenic soil acidification caused by nitrogen and acid addition significantly decreases microbial diversity, biomass, and functionality; in stark contrast, natural pH gradients exert only minimal effects on these microbial traits. …”

Raw data for figures and tables in the paper. by Runhai Jiang (19871068)

“…We employed broth culture and pot experiments to investigate the effect of the inoculation of <i>P</i>. …”

Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx by Ke He (331344)

“…The centroid ratio slightly decreased with increasing DBH, indicating that larger trees tend to have more ovate leaves than elliptical leaves. …”