FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx by Lei Jin (120473)

“…Background<p>Application of swine manure to soils exacerbates environmental antimicrobial resistance (AMR). However, a comprehensive evaluation of anaerobic digestion’s (AD) mitigation potential against AMR and its influencing factors in swine manure-to-soil systems remains lacking.…”

Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Table 1_Effect of membrane rigidification on the BrAFP1 expression and cold-tolerance in Brassica rapa.docx by Xiaoyun Dong (9706099)

“…</p>Results<p>The dimethyl sulfoxide (DMSO) treatment in the absence of cold exposure activated the transcriptional activity of proBrAFP1, a cold-inducible promoter; in contrast, benzyl alcohol (BA) treatment eliminated its cold-induced activation. …”

Image 3_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

DataSheet1_Transcriptomic and sugar metabolic analysis reveals molecular mechanisms of peach gummosis in response to Neofusicoccum parvum infection.zip by Yang Zhang (30734)

“…<p>Peach gummosis, a devastating disease caused by Neofusicoccum parvum, significantly shortens peach tree lifespan and reduces the yield of peach trees. …”

Image 2_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Image 1_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Table 4_Microbial dynamics in the ripening process of Vorarlberger Alpkäse: farm-specific variations at two Austrian alpine farms.xlsx by Johannes Josef Künz (22045286)

“…Introduction<p>Vorarlberger Alpkäse (VA) is a Protected Designation of Origin (PDO) Austrian heritage cheese produced from raw milk during the summer grazing period in the Alps. …”

“Engineering Rifampicin-Encapsulated Inhalable Microparticles for Precision Tuberculosis Therapy: In Vivo Distribution and Therapeutic Evaluation” by Ruchi Tiwari (6677939)

“…The TB-infected mice, which showed the lung tissue bacterial load was reduced to 3.2 log colony forming unit (CFU) and the levels of TNF-α were decreased while IL-10 levels were increased. With this kind of accelerated stability testing it was ascertained that the type of formulation had a shelf-life of 24 months.…”

Data Sheet 1_Microbial dynamics in the ripening process of Vorarlberger Alpkäse: farm-specific variations at two Austrian alpine farms.pdf by Johannes Josef Künz (22045286)

“…Introduction<p>Vorarlberger Alpkäse (VA) is a Protected Designation of Origin (PDO) Austrian heritage cheese produced from raw milk during the summer grazing period in the Alps. …”

Table 2_Microbial dynamics in the ripening process of Vorarlberger Alpkäse: farm-specific variations at two Austrian alpine farms.xlsx by Johannes Josef Künz (22045286)

“…Introduction<p>Vorarlberger Alpkäse (VA) is a Protected Designation of Origin (PDO) Austrian heritage cheese produced from raw milk during the summer grazing period in the Alps. …”

Table 1_Microbial dynamics in the ripening process of Vorarlberger Alpkäse: farm-specific variations at two Austrian alpine farms.xlsx by Johannes Josef Künz (22045286)

“…Introduction<p>Vorarlberger Alpkäse (VA) is a Protected Designation of Origin (PDO) Austrian heritage cheese produced from raw milk during the summer grazing period in the Alps. …”

Table 5_Microbial dynamics in the ripening process of Vorarlberger Alpkäse: farm-specific variations at two Austrian alpine farms.xlsx by Johannes Josef Künz (22045286)

“…Introduction<p>Vorarlberger Alpkäse (VA) is a Protected Designation of Origin (PDO) Austrian heritage cheese produced from raw milk during the summer grazing period in the Alps. …”

Table 3_Microbial dynamics in the ripening process of Vorarlberger Alpkäse: farm-specific variations at two Austrian alpine farms.xlsx by Johannes Josef Künz (22045286)

“…Introduction<p>Vorarlberger Alpkäse (VA) is a Protected Designation of Origin (PDO) Austrian heritage cheese produced from raw milk during the summer grazing period in the Alps. …”

Data Sheet 7_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Image 1_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.jpeg by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Data Sheet 3_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Table 2_Leucocalocybe mongolica inoculation enhances rice growth by reallocating resources from flavonoid defense to development via MYB/bHLH/WRKY networks.xlsx by Mingzheng Duan (11630632)

“…However, total flavonoid content decreased at the highest LY9 concentration, suggesting a metabolic trade-off between growth promotion and secondary metabolite production. …”