Data Sheet 1_Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study.xlsx by Jiayun Ling (15249289)

“…After 2 weeks of TCZ treatment, median (IQR) serum C3 levels declined from 1.45(1.27-1.75) g/L at baseline to 1.11 (0.97-1.18) g/L (a 23.45% reduction, P = 0.009), and C4 levels decreased from 0.29 (0.21-0.38) g/L to 0.13 (0.09-0.17) g/L (a 55.17% reduction, P = 0.005). …”

Data Sheet 1_Effectiveness of community-based management models in chronic obstructive pulmonary disease: a systematic review and meta-analysis.docx by Miao Zhan (2625718)

“…Notably, neither approach demonstrated a statistically significant advantage in improving quality of life among COPD populations, as assessed by the St. …”

Data Sheet 1_Campylobacter colonization and undernutrition in infants in rural eastern Ethiopia — a longitudinal community-based birth cohort study.docx by Dehao Chen (4966207)

“…</p>Results<p>The Campylobacter load in infant stools increased with age. The mean length-for-age Z-score (LAZ) decreased from −0.45 at 3–4 months of age to −2.06 at 13 months, while the prevalence of stunting increased from 3 to 51%. …”

Supplementary Material for: Abnormal Magnetic Resonance Imaging in the Medial Prefrontal Cortex Following Prenatal Alcohol Exposure and Placental Insufficiency in a Preclinical Mod... by figshare admin karger (2628495)

“…In the corpus callosum, the prenatal exposure/insult significantly decreased the AD (p<0.05; PAE+PI AD: 5.00x10-4 ± 4.60x10-5 mm2/s). …”

Table 1_Effect of compound kushen injection on immune function in patients with colorectal cancer: a systematic review and meta-analysis.docx by Lixin Zhang (55947)

“…Chemotherapy and radiotherapy remain cornerstone treatments; however, they often lead to significant immune suppression and an increased risk of infection. …”

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

Table 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.docx by Bei Li (90587)

“…Joinpoint regression analysis revealed the greatest decline in ASYR occurred in 2003–2008, while the most significant decrease in ASDR occurred in 1994–1999. …”

Table2_Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation.docx by Yangbai- Lu (19955883)

“…SNHG9 knockdown resulted in a significant increase in G1 phase cells and a decrease in S and G2 phases, indicating inhibition of DNA synthesis and cell cycle progression. …”

Table1_Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation.docx by Yangbai- Lu (19955883)

“…SNHG9 knockdown resulted in a significant increase in G1 phase cells and a decrease in S and G2 phases, indicating inhibition of DNA synthesis and cell cycle progression. …”

Ambient Air Pollutant Dynamics (2010–2025) and the Exceptional Winter 2016–17 Pollution Episode: Implications for a Uranium/Arsenic Exposure Event by Thomas Clemens Carmine (19756929)

“…PM₁₀ also shows a general decrease. CO appears relatively more stable.…”

Table 1_Changes in self-reported alcohol consumption at high and low consumption in the wake of the COVID-19 pandemic: a test of the polarization hypothesis.docx by Alexander Tran (11038679)

“…It was hypothesized that the COVID-19 pandemic led to a polarization of drinking–that is, heavy drinkers increased their drinking, while light to moderate drinkers decreased their drinking. …”

Optimal parameters and goodness of fit across stages and modalities. by Fernando Lehue (22513473)

Table_1_Validation of the CRAVE-C scale in Chinese adults: a four-study examination of competing motivations for physical activity versus rest.docx by Zhihui Cheng (296359)

“…In Study 4, the athlete group demonstrated a significant increase in “Move” desire from baseline to post-training, whereas the non-athlete group reported a significant decrease in “Move” desire from baseline to post-training.…”

Data Sheet 1_Adjunctive esketamine in propofol-based sedation for gastrointestinal endoscopy: a systematic review and meta-analysis of randomized trials.docx by Jiazheng Qi (22679312)

“…Esketamine added to propofol decreased involuntary movement (RR: 0.61, 95% CI: 0.42 to 0.92; P = 0.02; I² = 77.2%; low quality) and reduced the propofol consumption (mean difference [MD]: −0.94, 95% CI: −1.53 to −0.35 mg/kg; P < 0.01; I² = 96.2%; low quality). …”

Data Sheet 1_The efficacy and safety of danuglipron and orforglipron in patients with type 2 diabetes and obesity: a systematic review and meta-analysis.docx by Jingjing Zhou (179820)

“…Meta-analysis results demonstrated that danuglipron significantly decreased HbA1c (mean difference [MD]: −0.90; 95% CI: −1.06, −0.74), FPG (MD: −24.66; 95% CI: −30.45, −18.86) and weight (MD: −2.17; 95% CI: −3.10, −1.23) and improved FPI (MD: 2.94; 95% CI: 1.50, 4.38). …”

Table 1_Effects of different reduction patterns on stress distribution in patients with intertrochanteric fractures with intramedullary nail fixation: a finite element analysis.xls... by Jiajing Zhu (5117738)

“…</p>Results<p>As the head–neck fragment moved forward, the von Mises stress at the fracture surface, the proximal intersection point of the intramedullary nail, and the distal intersection point gradually decreased. This resulted in reduced fracture displacement, a significant decrease in trabecular bone volume, and a slight increase in the risk of screw cut-out. …”

Supplementary file 1_Soluble suppression of tumorigenicity-2 changes during cardiotoxic cancer treatment: a systematic review and meta-analysis.docx by Luca Fazzini (22599380)

“…Comparisons with Troponin and NT-proBNP showed a significantly higher Troponin SMD at T0-T1 (p = 0.027), while no significant differences were observed for NT-proBNP.…”

Table 1_The association between a dietary index for the gut microbiota and frailty in older adults: emphasising the mediating role of inflammatory indicators.docx by Huangyi Yin (18593848)

“…After adjusting for all of the covariates, each unit increase in the DI-GM was associated with a 6% decrease in the prevalence of frailty (OR = 0.94; 95% CI: 0.89, 0.99; p = 0.020). …”

From ice to flow: Tracing the transformation of glacial dissolved organic matter across a typical Tibetan Plateau glacier-lake-stream continuum by Yongqiang Zhou (11551027)

“…<p dir="ltr"><a href="" target="_blank">Mountain glaciers are melting at an accelerated rate due to global warming, thereby significantly altering proglacial and downstream hydrology</a>. …”

Enrollment and randomization. by Helene Høgsdal (21161981)

“…No significant findings were found in the intention-to-treat analyses, but the results from per-protocol analyses showed a decrease in hyperactivity problems among the adolescents that had used the app (<i>F</i>(4,1585) = 2.89, <i>p</i> =.021). …”