Supplementary file 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III tria... by Huaxiang Liu (322464)

“…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”

Supplementary Material for: The power of a good word: Enhancing the efficacy of analgesics in clinical settings by Treister R. (19801920)

“…In study 2, in the last two timepoints of assessment, participants in the EC arm also consumed fewer doses of opioids than participants in the RC arm (p<0.001). No significant differences were found in vital signs. Conclusions: We provide ecological evidence that positive information about treatment significantly decreases pain and opioid consumption during routine clinical care. …”

Key safety measures including adverse events. by Anuja Dokras (8679261)

“…<div><p>Background</p><p>The risk-to-benefit ratio of using combined oral contraceptive pills (COCPs) and/or metformin for comprehensive management of polycystic ovary syndrome (PCOS) in women with obesity is unclear. As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.…”

Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon... by Zejun Lu (2279458)

“…This case demonstrates that proton therapy is highly suitable for multifocal ACC metastases, especially multiple small pulmonary nodules. Through its precise dose delivery, it enables high-dose irradiation (GTV 60–70 Gy(RBE)) to targets while significantly sparing normal organs. …”

Clozapine for persons with neurodevelopmental disorders: a systematic review and expert recommendations for clinical practice by Hélène Verdoux (110251)

“…After clozapine initiation, a decreased frequency of challenging behavior persisting over time was reported in most participants included in clinical studies, and a significant reduction in the number of admissions in the population-based two-year mirror-image study. …”

Presentation1_Exchange flow in a highly stratified fjord in drought conditions.pdf by Elias Pinilla (20400329)

“…Using a high-resolution hydrodynamic model and the Total Exchange Flow (TEF) framework, we analyzed the impacts of river discharge, tides, and wind during a dry year (2016) and a typical year (2018). …”

Presentation 1_A framework for modeling county-level COVID-19 transmission.pdf by Yida Bao (15255682)

“…We then use Moran's I to evaluate spatial clustering, prompting Spatial Autoregressive and Spatial Error Models when autocorrelation is significant. …”

Supplementary Material for: EFFECT OF DIFFERENT DIALYSATE SODIUM CONCENTRATIONS ON BLOOD PRESSURE IN CHRONIC HEMODIALYSIS PATIENTS: A RANDOMIZED STUDY by figshare admin karger (2628495)

“…In the first group, we recorded a significant decrease in interdialytic weight gain and ultrafiltration volume in the first period and an increase in these parameters in the second. …”

Evidence of the Giant Barocaloric Effect in the PVA-Slime System by Molecular Dynamics Simulations by Richard Javier Caraballo-Vivas (22113727)

“…As a result, this contributes significantly to the change in internal energy and, consequently, to the barocaloric effect. …”

Evidence of the Giant Barocaloric Effect in the PVA-Slime System by Molecular Dynamics Simulations by Richard Javier Caraballo-Vivas (22113727)

“…As a result, this contributes significantly to the change in internal energy and, consequently, to the barocaloric effect. …”

Effect of fasudil on clinical outcomes of pulmonary hypertension: a systematic review and meta-analysis by Wanying Bao (19665769)

“…</p> <p>We conducted a systematic search in several databases. …”

Image1_The fruit fly Drosophila melanogaster as a screening model for antiseizure medications.JPEG by Florian P. Fischer (14457072)

“…Here, we explore the efficacy of a broad spectrum of ASMs in suppressing seizure activity in two established Drosophila melanogaster bang-sensitive mutants. …”

Supplementary Material for: Global, regional, and national burden of brain and central nervous system cancers for males from 1990 to 2021 and its predicted level in the next 25 yea... by Maimaiti A. (19938294)

“…Background: A study of the global burden of cerebral and central nervous system (CNS) cancers from the Global Burden of Diseases (GBD) indicates that these cancers significantly contribute to morbidity and mortality internationally. …”

Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study by Kazuaki Oyake (7481357)

“…</p> <p>This study aimed to determine whether orthostatic hypotension is more strongly associated with a marked cardiac output decrease or an impaired total peripheral resistance increase among individuals with stroke.…”

Image 5_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Image 2_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Table 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.docx by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Image 3_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Image 4_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”