ROS, K⁺ efflux and cathepsin B are required for NLRP3 activation. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. by Richard Junior Zapata Dongo (17912565)

Ba/F3 EML4-ALK^mutants exhibit variable dose-response to ABT-199 treatment. by Richard Junior Zapata Dongo (17912565)

Aging impairs renal mitochondrial function and antioxidant capacity. by Lihua Qiu (178071)

The loss of NLRP3 and AIM2 results in reduced Th17 and enhanced Th2 cytokine responses. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

Egg-induced IL-1β and IL-17 production is dependent on both Caspase-1 and Caspase-8. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

“…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. …”

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

“…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. …”

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

“…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. …”

<i>In vivo</i> treatment decreases bacterial burden and colonization of vital organs in a skin abscess biofilm infection model. by Robert L. Beckman I.V (22784303)

Aging enhances α-SMA expression and collagen accumulation in the kidney. by Lihua Qiu (178071)

Alterations in renal tubular morphology and renal interstitial collagen deposition were observed in aged mice. by Lihua Qiu (178071)

Aging regulates mRNA levels of renal fibrosis-related genes in mice across varying age cohort. by Lihua Qiu (178071)

Changepoint analysis in comparison of MarBTN-specific eDNA and cancer in hemolymph. by Rachael M. Giersch (22331947)

<i>shk-1</i> mutants display decreased glycogen storage. by Longjun Pu (20685717)

Pan-cancer analyses of ANGPTL4 expression and its prognostic significance in the TCGA database. by Yu Zhang (12946)

Pan-cancer analyses of NFKB2 expression and its prognostic significance in the TCGA database. by Yu Zhang (12946)

ALKG1202R –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALKC1156Y –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALKL1196M –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)