<b>Targeted Inhibition of Tumor-Intrinsic SIRPα Improve anti-PD-1 Resistance by Enhancing T Cell Immunity and Inhibits</b><b> Tumor </b><b>Proliferation in Esophageal Cancer: Thera... حسب Xi-Yang Tang (13184496)

"…Apoptosis of PBMC and Jurkat T cell were significantly decreased cocultured with SIRPA knockdown esophageal cells. …"

Image 1_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf حسب Xue Bai (129175)

"…Oxidative stress and lipid metabolism disorder-induced myocardial cell damage are part of the pathogenesis of DCM. In this study, we investigated the effects of alpha-mangostin (A-MG), a natural antioxidant extracted from mangosteen peel, on in vitro and in vivo DCM models.…"

Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). حسب Hong Yan Huang (20135965)

"…P4HA3 and Ki-67 were decreased in the knockdown groups by siRNA compared to the NC group. …"

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. حسب DIMITRIOS KIMOGLOU (20499350)

"…<br>Chronic stress disrupts the apoptotic process and contributes to<br>tumorigenesis. In particular, we seek to illustrate the epigenetic influence of stress on genes that control apoptosis, as well as the significance of the HPA axis as a therapeutic target for restoring cellular equilibrium. …"

Comparisons of separability and variance of evidence distributions when noise and variability are manipulated independently for the 4-layer CNN across the three experiments. حسب Medha Shekhar (19502698)

"…Comparisons using two-sided, pairwise t-tests showed that separability of evidence distributions increased significantly from the low- to high-contrast condition whereas the variance of evidence distribution decreased from the low- to high-contrast conditions for all experiments except Experiment 3. …"

Changes of wind direction, wind speed and specific <i>orf2</i> amplicons during typhoon events for a range of years (2019–2020, n حسب Kuang-Yueh Chen (21071954)

"…Shades of blue, from dark (6-8 m/sec, largest) to light (0-2 m/sec, smallest), divided into 4 intervals, represent decreasing average wind speeds per hour (A). Comparison of aerosol concentrations (median values) between the north and south sides of the hills is illustrated (B, left), and the comparison of average northwesterly wind speeds per hours (median values) between the same regions, during typhoon landing, is illustrated (B, right). …"

Caffeine induces proteome-wide changes in a Rob-dependent manner. حسب Christoph Binsfeld (21763112)

"…Horizontal and vertical lines correspond to p-value = 0.05 and log₂(fold-change) = 0, respectively. n refers to the total number of proteins detected. The double-sided Fisher’s exact test p-value for enrichment of OMPs among significantly decreased proteins is shown. …"

Simultaneous Determination of the Bioavailable Fraction of Eight Elements in Soil Using an Automated Extraction Device and Inductively Coupled Plasma - Optical Emission Spectrometr... حسب Yigang Ma (22124655)

"…Compared with manual methods, the relative standard deviation (RSD) of element detection has been significantly reduced, with values decreasing from 2.01%–23.5% to 1.54%–9.69%. …"

Supplementary Material for: Assessment of the Factors Influencing Early Detection Practices of Oral Carcinomas by Dentists: A Cross-Sectional Study حسب figshare admin karger (2628495)

"…With increasing duration, the early detection practice scores decreased. Moreover, “guidelines about OC examinations” significantly predicted practice scores (higher scores where written guidelines were present) (P<0.001). …"

Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer حسب Xiaoxiao Sun (20589448)

"…Statistical comparisons between groups were based on the integrated confluence over time (area under curve; AUC), using one-sided Mann–Whitney tests. The significance of the results is indicated by symbols: *, <i>P</i> ≤ 0.05; **, <i>P</i> ≤ 0.01; ****, <i>P</i> ≤ 0.0001.…"

LRIG1 and CDK6 expression in the lateral ventricular wall cells حسب Hyung-song Nam (8914220)

"…Although the <i>Cdk6</i> mRNA decreases significantly in the neuroblasts, the DCX+ neuroblasts still show a lot of td-sfGFP immunoreactivity.…"

Applications of Human Biostasis in Crewed Space Exploration حسب Josh Universe (21186797)

"…NASA's STASH program and ESA's hibernation research mark essential steps forward in torpor research, indicating growing institutional support for these technologies.…"