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Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease
Published 2019“…Lower CSF levels of Aβ1–42, total tau and P-tau181p were significantly related to worsening of some motor and/or cognitive functions. …”
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Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis
Published 2022“…Microbial dysbiosis caused by RV infection may significantly influence disease prognosis and the development of other chronic diseases. …”
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Large scale association analysis identifies three susceptibility loci for coronary artery disease
Published 2011“…Replication of the most significantly associated polymorphisms in multiple populations with distinctive genetic backgrounds and lifestyles is crucial to the understanding of the pathophysiology of a multifactorial disease like CAD. …”
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Evaluation of Neuro Images for the Diagnosis of Alzheimer's Disease Using Deep Learning Neural Network
Published 2022“…<div><p>Alzheimer's Disease (AD) is a progressive, neurodegenerative brain disease and is an incurable ailment. …”
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Health-related quality of life in adults with transfusion-independent thalassaemia intermedia compared to regularly transfused thalassaemia major
Published 2011“…Background: In patients with β thalassaemia intermedia (TI), the milder anaemia and transfusion independence imply better health-related quality of life (HR-QoL). However, the unbalanced pathophysiology of the disease allows for several serious clinical complications to manifest, which may have a negative impact on HR-QoL. …”
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A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar
Published 2023“…Higher parental educational levels, maternal employment, and having a positive family history of obesity and/or overweight in first-degree relatives were significantly associated with adverse lifestyle changes during schools’ closure.…”
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Clinical relevance of aortic stiffness in end-stage renal disease and diabetes : implication for hypertension management
Published 2018“…In patients with ESRD, more specific and potentially modifiable kidney disease-related parameters such as phosphocalcic disorders and vitamin K deficiency, appear correlated with aortic calcification and cf-PWV. …”
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Advances in Huntington’s Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review
Published 2025“…<p dir="ltr">Neurodegenerative disorders (NDs) cause progressive neuronal loss and are a significant public health concern, with NDs projected to become the second leading global cause of death within two decades. …”
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Cerebrospinal α‐Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort
Published 2023“…<p></p><div> <h3> Background</h3> <p>Tangible efforts have been made to identify biomarkers for Parkinson's disease (PD) diagnosis and progression, with α-synuclein (α-syn) related biomarkers being at the forefront.…”
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Published 2021“…Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …”
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Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson’s Disease
Published 2015“…This treatment also significantly reduced dopaminergic neuronal loss in the injected substantia nigra and preserved dopaminergic fibers in the ipsilateral striatum. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…A hybrid pharmacophore model, based on structural motifs previously identified by our team, was employed to generate ligands that simultaneously target COX-2, 15-LOX, and PPARγ in the context of metabolic dysfunction-associated fatty liver disease (MAFLD). Notable COX-2 inhibitory activities (IC50 = 0.065–0.24 μM) were observed relative to celecoxib (IC50 = 0.049 μM). …”
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Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort
Published 2021“…As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. …”
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Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study
Published 2024“…<h3>Introduction</h3><p dir="ltr">Alzheimer’s Disease (AD) is complex and novel approaches are urgently needed to aid in diagnosis. …”
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Comparison of the Effects of 15 and 60 ,ug/kg Fentanyl Used for Induction of Anesthesia in Patients with Coronary Artery Disease
Published 1985“…Subsequent differences in HR were not significant. There were no dose-related differences in mean arterial pressure, cardiac index, central venous pressure, or pulmonary capillary wedge pressure. …”
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Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review
Published 2022“…<p dir="ltr">Coronavirus disease 2019(COVID-19) is an ongoing global pandemic with a daily increasing number of affected individuals and a relatively high mortality rate. …”
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Relationship between pharmaceutical pricing strategies with price, availability, and affordability of cardiovascular disease medicines: surveys in Qatar and Lebanon
Published 2022“…The study aimed to assess prices, availability, and affordability of essential cardiovascular disease medicines in relation to pricing strategies in Qatar and Lebanon.…”
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