Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx by Lillia A. Baird (10575941)

“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”

Data Sheet 1_Yeast cell wall derivatives as a potential strategy for modulating oral microbiota and dental plaque biofilm.docx by Torsten P. M. Scheithauer (10950975)

“…</p>Conclusion<p>This study has demonstrated the potential of yeast cell wall derivatives to positively impact oral health by significantly reducing biofilm density, modulating the oral microbial composition, and decreasing the production of short-chain fatty acids. …”

Supplementary Material for: Phosphorus restriction prevents rapamycin-induced kidney damage in rats by Raya A.I. (19823163)

Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx by Dehua Luo (22275916)

“…</p>Results<p>Resveratrol markedly attenuated collagen deposition and reduced hydroxyproline levels, a central marker of fibrotic progression. It significantly inhibited the accumulation of extracellular matrix components and modulated profibrotic mediators. …”

Modulating Aesthetic Furniture Preferences through Music: A Multimodal Neurophysiological Study Using Neural Ordinary Differential Equations Networks by Jiufang Lv (20807355)

“…</p><p dir="ltr">The findings revealed that musical intervention significantly modulated neural activity in specific frequency bands: prediction error for tactile density in the Alpha band decreased by 26.9%, while prediction accuracy for exquisiteness in the Beta band improved significantly. …”

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Supplementary Material for: m6A eraser FTO promotes ATF3 expression impairing podocyte autophagy in diabetic nephropathy by figshare admin karger (2628495)

“…Here, we identify the m6A demethylase FTO as a critical driver of DN. FTO expression is significantly upregulated in podocytes from patients with DN and correlates with increased expression of ATF3, which acted as a transcriptional repressor inhibiting podocyte autophagic flux. …”

Image 1_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Image 2_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx by Aierpati Moheteer (21522284)

“…Therapeutic evaluation in a DSP nanoparticles-treated mouse liver hydatid model revealed that the DSP nanoparticles-H group significantly reduced liver, spleen, and vesicle weights compared to both control and albendazole (ABZ)-treated groups (P <0.05). …”

Dataset for Generative artificial intelligence models in clinical infectiousdisease consultations: a cross-sectional analysis among specialists andresident trainees by Kwan Yeung Edwin Chiu (20718422)

“…Specialists consistently rated the responses more favorably than resident trainees, highlighting a discrepancy in clinical judgment. Cost analysis revealed decreasing operating expenses over time, but model performance was not directly correlated with cost. …”

Table 1_The association between oxidative balance scores and all-cause mortality and cancer-specific mortality in cancer survivors: a retrospective cohort study.doc by Ran He (207626)

“…A similar significant association was found with cancer-specific mortality, while no significant association was noted for CVD mortality. …”

Data_Sheet_1_MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.pdf by Nandita Bodra (19793703)

“…Through deletion mutant analysis, we found that individual deletions of makC or makD do not significantly affect MakA expression or secretion. However, the deletion of both makC and makD impairs the expression of MakB, which is directly downstream, and decreases the expression of MakE, which is separated from makCD by two genes. …”

Supplementary Material for: Glucosamine use reduces the risk of first-ever optic neuritis: A nationwide 16-year longitudinal analysis by Yang Y.-Y. (4130872)

“…Conclusion: Taiwanese glucosamine users have a decreased risk of developing ON. Our work provides a theoretical basis for expanding glucosamine indications in regions with minimal prevalence of ON.…”

Table 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx by Carlos A. R. Sánchez (21288050)

Supplementary Material for: Safety profile of intravitreal Dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies. by figshare admin karger (2628495)

“…In general, the peak IOP increase was typically observed 60 days post-DEX-i injection, followed by a decrease in the subsequent months. In most patients, these IOP-related AEs were successfully and efficiently managed with topical IOP-lowering medication, although some patients required additional treatments (i.e., laser or surgery). …”