<i>Aspergillus fumigatus</i> effector crpA orchestrates host prostaglandin signaling to promote fungal virulence by Gustavo Goldman (8849927)

“…Murine macrophages exposed to Δ<i>crpA </i>conidia produce significantly higher levels of the prostaglandins PGE2 and PGD2, suggesting that deletion of CrpA modulates cytokine production through effects on eicosanoid signaling. …”

Photon budgets and the effects of relative CDOM and pigment absorptions on primary production along a coastal salinity gradient by Aleksandr Berezovski (20459366)

“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”

Image 1_Integrating salpingoscopy and immunohistochemistry to improve tubal infertility diagnosis: a retrospective cohort study.png by Adalyat Alenova (22696712)

“…In contrast, the composite prognosis score demonstrated a strong positive correlation with treatment success (r = 0.578; p < 0.0001).…”

Image 2_Integrating salpingoscopy and immunohistochemistry to improve tubal infertility diagnosis: a retrospective cohort study.jpeg by Adalyat Alenova (22696712)

“…In contrast, the composite prognosis score demonstrated a strong positive correlation with treatment success (r = 0.578; p < 0.0001).…”

Adverse events in patients with castration-resistant prostate cancer treated with ra-223: a retrospective pharmacovigilance study by Lei Yang (102719)

Supplementary Material for: Efficacy of penetrating canaloplasty versus trabeculectomy in patients with bilateral primary glaucoma: a self-control study by figshare admin karger (2628495)

“…Complete (without medication) and qualified success (with/without medication) were defined as IOP ≤21 mmHg and ≥20% IOP reduction. Results: Mean IOP decreased from 32.5±8.87mmHg on 2.3±1.43 medications at baseline to 14.6±4.41mmHg on 0.20±0.58 medications at 12 months in TRAB group (both p<0.0001) and from 30.0±9.61mmHg on 2.7±1.10 medications to 14.8±4.63mmHg on 0.12±0.44 medications in PCP group (both p<0.0001). …”

Impact of previous cesarean delivery on reproductive outcomes of assisted reproductive technology: a Bayesian network meta-analysis by Kun Ma (126624)

“…Furthermore, CSD had a lower live birth rate than CS (RR = 0.75, 95% CI 0.59-0.95, <i>p</i> < 0.05); ICF decreased both clinical pregnancy rate (RR = 0.72, 95% CI 0.51-0.95, <i>p</i> < 0.05) and live birth rate (RR = 0.71, 95% CI 0.49-0.97, <i>p</i> < 0.05) compared with CS.…”

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx by Xuan Zhao (356028)

“…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …”

Identification of multicohort-based predictive signature for NMIBC recurrence reveals SDCBP as a novel oncogene in bladder cancer by Chen Zhang (66790)

“…<p>Despite surgical and intravesical chemotherapy interventions, non-muscle invasive bladder cancer (NMIBC) poses a high risk of recurrence, which significantly impacts patient survival. …”

Table 1_Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis.docx by Yichuan Xv (18702754)

“…The meta-analysis showed a significantly higher overall response rate in the acupuncture group than the control group [RD = 0.16, 95% CI (0.11, 0.21), p < 0.001]. …”

Supplementary Material for: Exclusively macular phenotype of non-syndromic MFSD8-related disease: A Case Report by figshare admin karger (2628495)

“…Introduction: The purpose of this report is to highlight the clinical phenotype and imaging findings in a patient with an exclusively macular phenotype of non-syndromic MFSD8-related disease, and to provide clinical evidence for pathogenicity reclassification of a variant of uncertain significance (VUS) MFSD8 c.291G>C (p.Trp97Cys). …”

Supplementary Material for: Perioperative Blood Pressure Management Recommendations in Pediatric Pheochromocytoma: A 10-Year Narrative Review by Ambarsari C.G. (16518681)

“…Nevertheless, mortality rates decreased significantly in the latter half of the twentieth century due to effective perioperative blood pressure (BP) management. …”

Table 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx by Peijin Li (220400)

“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”

Table 1_The efficacy of infliximab combined with partial enteral nutrition in the treatment of Crohn’s disease: a cohort study.docx by Chen Huang (202847)

“…</p>Results<p>Among the 176 included patients, 99 (56%) were in the IFX monotherapy group, and 77 (44%) were in the IFX + PEN group. A significantly higher proportion of patients in the IFX + PEN group achieved clinical response (defined as a CDAI decrease ≥70 points) compared to those in the IFX group at 14 weeks (87.01% vs. 74.75%, p = 0.043), as well as a higher proportion achieving endoscopic remission at 54 weeks (84.42% vs. 65.66%, p = 0.005). …”

Table 1_The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuate Pseudomonas aeruginosa virulence.docx by Jun Ying (129597)

“…</p>Results<p>C-PC attenuated biofilm formation, pyocyanin synthesis, motility, and PQS signaling molecule production. Moreover, C-PC significantly downregulated the transcription levels of QS-related genes in PA2, including pqsA and pqsR, as well as the expression of virulence factor genes phzA, lasA, lasB, flgF, fliE, exoS, exsA, lecA, popB, vasG, chiC, pelF, pslB, qseB, and pgsR. …”

Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx by Adam D. Price (19842741)

“…Introduction<p>Sepsis is a complex clinical syndrome characterized by a heterogenous host immune response. …”

Image2_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg by Adam D. Price (19842741)

“…Introduction<p>Sepsis is a complex clinical syndrome characterized by a heterogenous host immune response. …”

Image3_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg by Adam D. Price (19842741)

“…Introduction<p>Sepsis is a complex clinical syndrome characterized by a heterogenous host immune response. …”

Image1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg by Adam D. Price (19842741)

“…Introduction<p>Sepsis is a complex clinical syndrome characterized by a heterogenous host immune response. …”

Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX by György Szklenarik (20296893)

“…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …”