Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model حسب Merel Wauters (21333023)

"…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …"

Data Sheet 1_Quantitative MRCP metrics as imaging biomarkers to differentiate benign from malignant bile duct obstructions.docx حسب Kulyada Eurboonyanun (12548926)

"…If detected early, surgical resection carries a 35% 5-year survival rate; this decreases to <11% 1-year survival rate when detected at later stages. …"

Data_Sheet_1_Guanxin Danshen Formulation Protects against Myocardial Ischemia Reperfusion Injury-Induced Left Ventricular Remodeling by Upregulating Estrogen Receptor β.DOC حسب Xuehong Deng (13924952)

"…<p>Background: Guanxin Danshen formulation (GXDSF) is a traditional Chinese herbal recipe recorded in the Chinese Pharmacopeia since 1995 edition, which consists of Salviae miltiorrhizae Radix et Rhizoma, Notoginseng Radix et Rhizoma and Dalbergiae odoriferae Lignum. …"

Depletion of viral UL87 LTF in late infection does not affect viral long promoter transcription. حسب Qiaolin Hu (8677473)

"…<b>(B)</b> UCSC Genome Browser of the MIE promoter/enhancer and downstream region show that dTag degrader treatment significantly decreased transcription from the LTF-dependent UL124 promoter and enhancer promoter EP2 (gold arrowheads). …"

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf حسب Alex Ramos (16267028)

"…Background<p>Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. …"

Image 3_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg حسب Shuting Hua (21264785)

"…The decline in disease burden was most pronounced in high-SDI regions, while low-SDI regions faced a significantly higher disease burden and exhibited notable regional disparities. …"

Supplementary file 1_Effects of microbial organic fertilizers on soil microbial communities and physicochemical properties in tobacco cultivation.docx حسب Shengli Wang (4318522)

"…Furthermore, an assessment of tobacco leaf morphology, yield, and quality demonstrated that the application of MOF resulted in a 21.93% increase in leaf yield and a 27.38% increase in yield value per unit area. …"

Data Sheet 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx حسب Manling Zhang (566460)

"…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…"

Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx حسب Manling Zhang (566460)

"…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…"

Image 2_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg حسب Shuting Hua (21264785)

"…The decline in disease burden was most pronounced in high-SDI regions, while low-SDI regions faced a significantly higher disease burden and exhibited notable regional disparities. …"

Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of... حسب Xiaoqing Xia (14607269)

"…</p>Results<p>The number of IHD deaths and DALYs resulting from non-optimal temperature experienced a rise of 71.6% and 60.6%, respectively. And it showed regional imbalances: in the region with low-middle socio-demographic index (SDI), it was increased [EAPC for ASMR: 0.39% (95% CI: 0.2%, 0.58%), EAPC for ASDR: 0.33% (95% CI: 0.15%, 0.52%)], while decreased in the high SDI region, [EAPC for ASMR: −3.44% (95%CI: −3.58%, −3.3%), EAPC for ASDR: −3.18% (95%CI: −3.32%, −3.03%)]. …"

Image 1_Tanyu Tongzhi Formula relieves the progression of atherosclerotic plaque through lipid regulation and anti-inflammatory effects.jpeg حسب Tingting Chen (111216)

"…Objective<p>Tanyu Tongzhi Formula (TTF), a clinically proven empirical prescription, has been utilized to treat atherosclerosis (AS) for decades. …"

Image 1_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg حسب Shuting Hua (21264785)

"…The decline in disease burden was most pronounced in high-SDI regions, while low-SDI regions faced a significantly higher disease burden and exhibited notable regional disparities. …"

Data Sheet 1_Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.docx حسب Zongjiang Zhao (21215822)

"…Background<p>Wenshenyang decoction (WSY) has been shown to have a considerable effect on restoring renal function and improving kidney Yang deficiency syndrome in patients with CKD. …"

Using high-temperature-modified graphene to alleviate pore pressure in concrete under high temperatures حسب Yongpeng Zeng (10089160)

"…While the compressive strength decreased slightly with graphene at room temperature (6.9%, 16% and 50.9% reductions at 5, 10 and 15 wt.%, respectively), the residual strength loss after 400 °C was significantly lower: 46.3%, 17.8%, and 29.0% for 5, 10, and 15 wt.% MGP, respectively, compared to 72.9% in the control group. …"

Global Mortality and DALYs for CVD by Sex (1990-2021). حسب Rongxiang Zhang (16537599)

"…Females experienced a consistently higher burden, with significantly higher age-standardized mortality rates and DALY values compared to males, emphasizing persistent gender disparities in CVD outcomes related to LPA.…"

The interaction of COVID-19 and sociodemographic factors on pediatric rehabilitation service initiation حسب Lynn R. Tanner (21311527)

"…</p> <p>During COVID, service initiation decreased significantly by 23% (<i>p</i> < 0.001), whereas referral rates remained stable. …"

Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx حسب Na Zhu (331131)

"…After adjusting for all confounders, LC9 was significantly and negatively associated with both MASLD (OR = 0.59, 95% CI: 0.54–0.64) and hepatic fibrosis (OR = 0.66, 95% CI: 0.45–0.97), with each 10-point increase in the LC9 score decreasing the prevalence by 41% and 34%, respectively. …"

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx حسب Zhijie Zhuang (17669958)

"…</p>Results<p>The weighted average serum Klotho concentrations decreased significantly across MDS groups (low: 864.50, middle: 805.67, high: 755.02 pg.…"

DataSheet1_Reduce the application of phosphorus fertilizer in peanut fields and improve its efficiency by using iron modified biochar to adsorb phosphorus recovery products.docx حسب Junxiao Zhang (421908)

"…</p>Results<p>The results demonstrated that the biochar dosage of 0.05 g (2 g L^-1) results in a phosphate removal rate exceeding 80%. Optimal adsorption efficiency occurs within a pH range of 6-9, with a sharp decline observed at pH values above 10. …"