Data Sheet 1_Impact of implementing a pediatric early warning system on outcomes in hematopoietic stem cell transplant units in South America and Europe.docx by Monica L. Quijano-Lievano (22808537)

“…CDE post-PEWS were less likely due to respiratory distress (38%, n = 27/71 vs. 23% n = 35/150, p = 0.0348), had fewer organ systems with dysfunction at ICU transfer (median 2 [IQR 1–3] vs. 0 [IQR 0–2], p < 0.001), and had lower PIM2, which indicates a lower severity of illness at ICU transfer (median 5.0 [IQR 1.4–7.9] vs. 1.5 [IQR 1.2–3.4], p < 0.001). There was a non-significant decrease in clinical deterioration event mortality post-PEWS implementation (24%, n = 17/71 vs. 15%, n = 22/150, p = 0.1335).…”

Data for Will et al. 2025 Resting metabolic rate is repeatable, but does not affect call characteristics, in the gray treefrog <i>Hyla chrysoscelis</i> by Phoebe Will (20819362)

“…Nevertheless, RMR was significantly repeatable. We found that RMR decreased across the breeding season, which reduced the consistency in RMR measurements of the same individual over time. …”

Table 1_Effects of eculizumab and rituximab on visual function, motor function and social quality in patients with NMOSD: a comparative study.docx by Yihan Liu (2258221)

“…Social function (SFS) improved significantly in both groups, with greater gains in the EG (P < 0.001). …”

Image_1_Exploring the association between phytopharmaceutical use and antibiotic prescriptions in upper respiratory infections: results from a German cohort study evaluating the im... by Anna-Jasmin Wetzel (17837840)

“…</p>Conclusion<p>Prescriptions of phytopharmaceuticals were significantly associated with a decrease antibiotic prescriptions among GPs, especially when combined with naturopathy qualifications. …”

Table 1_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx by Xinhui Yang (12051251)

“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”

Table_1_Exploring the association between phytopharmaceutical use and antibiotic prescriptions in upper respiratory infections: results from a German cohort study evaluating the im... by Anna-Jasmin Wetzel (17837840)

“…</p>Conclusion<p>Prescriptions of phytopharmaceuticals were significantly associated with a decrease antibiotic prescriptions among GPs, especially when combined with naturopathy qualifications. …”

Table 3_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx by Xinhui Yang (12051251)

“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”

Table 2_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx by Xinhui Yang (12051251)

“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”

EPB-113 binds to hexameric nsp15 protein. by Benjamin Van Loy (9496075)

“…The top panel shows the curves generated from the mean data of three independent experiments. The graph (bottom panel) shows the melting temperatures (individual and mean values) in three independent experiments. …”

Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

“…While some previous studies reported that CYP3A5 variants were associated with decreased blood pressure and risk of HTN, others reported no associations. …”

Raw data for hand and arm dysfunction following hemodialysis access placement by Kyoungrae Kim (10312460)

“…RESULTS: Six weeks post-surgery, patients exhibited significant functional decline in the access limb. Postoperative grip strength declined by approximately 15% (P=0.0015), finger pressure decreased by ~30 mmHg (P<0.0001), and the perceived HAD score increased significantly (P=0.0450) compared to the preoperative values. …”

Data Sheet 1_Crosstalk between MSC-extracellular vesicles and Olea europaea leaf extract in encapsulated liposomal hydrogel: attenuation of neuroinflammation and brain neurotransmi... by Doaa Ibrahim (12910718)

“…The HFD-fed group exhibited greater glucose intolerance and increased body weight gain; however, these effects were significantly reversed in the group treated with the combination of Lipo-OLE-Hydrogel and MSC-Exo, even after long-term HFD induction. …”

DtpT transports structurally diverse di-/tripeptides. by Imran Khan (109715)

“…(<b>C</b>) Transport of 20 peptides was compared by quantifying the change in pyranine fluorescence over the first 30 seconds of the assay. Bars indicate the mean of three replicates ± standard deviation. Coloured bars indicate a change in fluorescence which differs significantly from the no peptide (“Water”) control. …”

<b>Climate warming, rather than nitrogen deposition, reduces plant diversity and increases community homogenization in a desert steppe</b> by Yi Zhu (22625741)

“…Over this period (2006–2022), warming (mean annual temperature + 1.4°C) significantly decreased species richness and functional α-diversity throughout the experiment, whereas its effects on phylogenetic α-diversity and community phylogenetic structure were significant only before 2015 and disappeared thereafter, likely due to an extreme drought that reset the community composition. …”

Table 2_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 3_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Image 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.jpg by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”