Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization by Xiaomin Wu (20328165)

“…<p dir="ltr"><b>Background:</b><b> </b>Heatstroke (HS) is a critical medical condition resulting from increased body temperatures, which can lead to significant damage to the central nervous system (CNS). …”

Table 1_Effect of heat-killed Lacticaseibacillus paracasei KW3110 on mild to moderate seasonal allergic rhinitis symptoms in Japanese adults: a randomized, double-blind, placebo-co... by Yoshihiko Sugihara (2314381)

“…Diagnosis by an otorhinolaryngologist showed a significant decrease in the score of “paroxysmal sneezing or rhinorrhea” (p < 0.05) and “classification of severity of allergic rhinitis symptoms” (p < 0.05) at 4 weeks, and the number of subjects scoring “worse” (p < 0.05) in the efficacy assessment.…”

Table 1_Characteristics of myocardial work during exercise stress echocardiography in healthy adults.pdf by Liwei Huang (7165781)

“…</p>Results<p>GWI, GCW, and GWW increased, while GWE decreased after exercise. There were no significant differences in any of the global MW parameters between sexes at rest (all p > 0.05). …”

Image 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.tif by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Table 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.docx by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Droperidol is associated with reduced length of stay in the treatment of cannabinoid hyperemesis syndrome by Geoffrey S. Kelly (21537766)

“…After adjustments, droperidol use was associated with a reduced length of stay (mean ratio 0.76; 95% CI: 0.62 0.94; <i>P</i> = 0.01), decreased total medication administration (OR 0.34; 95% CI: 0.20–0.58; <i>P <</i>0.001) and decreased usage of opioids (OR 0.16; 95% CI: 0.07–0.39; <i>P <</i>0.001). …”

The effect of EDF derived from <i>E</i>. <i>coli</i> (in mid-logarithmic growth phase, OD = 0.6) on the MRSA and MSSA. by Shahriar Bakhti (20391188)

“…In all the analyses, p<0.05 was considered statistically significant. The data were expressed as the mean value plus–minus the standard error of the mean (mean ± SEM).…”

Data Sheet 1_The SlDLK2 receptor, involved in the control of arbuscular mycorrhizal symbiosis, regulates hormonal balance in roots.docx by Martín Ramos-Alvelo (20413940)

“…Stable transgenic SlDLK2 overexpressing (OE) tomato lines were obtained, and hormone contents were analyzed in their roots and leaves. Interesting significant hormonal changes were found in roots of SlDLK2 OE lines with respect to the control lines, with a strong decrease on jasmonic acid and ABA. …”

Supplementary file 1_Patterns in (es)citalopram prescriptions to Medicaid and Medicare patients in the United States: the potential effects of evergreening.docx by Luke R. Cavanah (19022435)

“…This retrospective study focuses on characterizing the chronologic and geographic variation in the use of citalopram and escitalopram from 2015 to 2020 among US Medicaid and Medicare patients. We hypothesized that prescription rates of citalopram will decrease with a concurrent increase in escitalopram, consistent with “evergreening”.…”

Image 2_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…In this study, we utilized an in vitro human umbilical cord blood-derived CD34⁺ cell-based erythroid differentiation system, alongside a murine model, to investigate the impact of PLK1 inhibitors on erythropoiesis. …”

Table 1_Flammulina velutipes mycorrhizae dietary fiber attenuates the development of obesity via regulating lipid metabolism in high-fat diet-induced obese mice.xlsx by Fengjuan Jia (703605)

“…Introduction<p>Mounting evidence has shown that Flammulina velutipes mycorrhizae dietary fiber (Fv-DF) has the potential to significantly improve health outcomes by addressing lipid metabolic disorders. …”

Video 2_Takotsubo syndrome following mitral transcatheter edge-to-edge repair: a case report and literature review.mp4 by Si Pang (5959094)

“…Background<p>Takotsubo syndrome (TTS), characterized by transient wall motion aberrations and clinical manifestations akin to acute coronary syndrome, predominantly arises from significant physical or emotional stress, often throughout the perioperative period. …”

Table1_Tle6 deficiency in male mice led to abnormal sperm morphology and reduced sperm motility.docx by Kousuke Kazama (19937214)

“…In addition, Tle6^+/− mice exhibited a significant increase in serum testosterone levels compared to wild-type mice. …”

Data Sheet 1_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.xlsx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Video 5_Takotsubo syndrome following mitral transcatheter edge-to-edge repair: a case report and literature review.mpg by Si Pang (5959094)

“…Background<p>Takotsubo syndrome (TTS), characterized by transient wall motion aberrations and clinical manifestations akin to acute coronary syndrome, predominantly arises from significant physical or emotional stress, often throughout the perioperative period. …”

Supplementary Material for: Role of melatonin in intestinal mucosal injury induced by chronic restraint stress in mice by figshare admin karger (2628495)

“…Results: Mice subjected to restraint stress presented elevated CORT and NE levels of 141.41% and 151.24%, respectively, and a decreased plasma MT content of 37.12%. Consistent with the decrease in MT levels, we observed a reduction in antioxidant ability and autophagic proteins and increased apoptotic protein levels in the gut, resulting in injury to the intestinal mucosa, which manifested as reductions in the villus height and the V/C ratio; the number of goblets; the number of mast and PCNA-positive cells; and the expression of tight junction proteins (ZO-1, occludin and claudin-1). …”

Supplementary Material for: Acute myelin oligodendrocyte glycoprotein (MOG)-IgG optic neuritis without optic nerve enhancement by Jeyanathan B. (20374227)

“…While acute MOG-ON usually presents with optic nerve enhancement, recognizing atypical presentations is critical in accurate diagnosis and effective management. Case Presentation: We herein present a case of a 67-year-old woman presenting with sudden decrease in vision in the right eye. …”

Table 1_Antimicrobial susceptibility profiles of commensal Clostridium perfringens isolates from chickens in Hungarian poultry farms between 2022 and 2023.docx by Ádám Kerek (14263613)

“…</p>Methods<p>In this study, we aimed to assess the antibiotic susceptibility of commensal Clostridium perfringens (C. perfringens) strains (n = 146) isolated from largescale poultry farms in Hungary, using minimum inhibitory concentration (MIC) determinations. …”

Video 4_Takotsubo syndrome following mitral transcatheter edge-to-edge repair: a case report and literature review.mpg by Si Pang (5959094)

“…Background<p>Takotsubo syndrome (TTS), characterized by transient wall motion aberrations and clinical manifestations akin to acute coronary syndrome, predominantly arises from significant physical or emotional stress, often throughout the perioperative period. …”

Exposed mosquitoes with fractional order and . by Sisay Fikadu Jaleta (20912783)

“…<div><p>Malaria remains a significant global health challenge, particularly in developing countries. …”