Table 1_Sex disparities in the risk of intracranial aneurysm rupture: a case–control study.docx by Dong Shen (485693)

“…In the subgroups based on the covariates used in this study, we only identified statistically significant interaction between sex and age. …”

Table 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Table 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx by Yali Han (4676677)

“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”

Improved antidiabetic potential of quercetin-loaded chitosan–lecithin nanoparticles for effective glycaemic control by Mohammad Zaki Ahmad (13117814)

“…However, its clinical use is limited by poor solubility and bioavailability. We developed the QTN loaded chitosan–lecithin nanoparticles (QTN/LCHS-NPs) to enhance its therapeutic profile.…”

<b>Differential Effects of Retinol-Binding Protein 3 and Anti-VEGF Antibodies on Retinal Dysfunctions in Diabetic Retinopathy</b> by Qin Li (36669)

“…Since elevation or overexpressing retinol binding protein 3 (RBP3) decreased risks for retinal pathologies and progression to severe DR, we compared the therapeutic profile of RBP3 and anti-VEGF to normalize retinal dysfunctions induced by diabetes. …”

<b>Social conditions alter the growth, metabolic rate, behavioral traits, and food-shelter preferences in the qingbo </b><b><i>Spinibarbus sinensis</i></b> by Yu-Lin Zhang (9129227)

“…These findings suggest that visual social isolation may not be a significant stressor for qingbo, as the isolation-reared qingbo exhibited improved growth. …”

DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”

Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx by Yuwei Mi (18003969)

“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”

DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”

DataSheet1_Engineered myeloid precursors differentiate into osteoclasts and resorb heterotopic ossification in mice.docx by Cameron Rementer (20310858)

“…Once symptomatic, HO causes pain, limited mobility and decreased quality of life. Current treatments are limited and have significant complications with high recurrence rates, underscoring the need for improved therapeutic interventions. …”

Image 1_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff by Songtao Li (186776)

“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”

Table 1_Cross-education: motor unit adaptations mediate the strength increase in non-trained muscles following 8 weeks of unilateral resistance training.xlsx by Edoardo Lecce (20518145)

“…These gains were accompanied by significant decreases in motor unit recruitment thresholds (p < 0.01) and higher net discharge rate (i.e., gain in discharge rate from recruitment to peak) following intervention (p < 0.05). …”

Image2_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”

Alterations in gut microbiota and plasma metabolites in patients with generalized anxiety disorder: a multi-omics study by Yi Li (1144)

“…</p> <p>Ninety subjects (60 patients with GAD and 30 healthy volunteers) were included. We employed 16S rRNA gene sequencing to characterize the gut microbiota and targeted liquid chromatography–mass spectrometry to analyze plasma metabolomic profiles.…”

Table 2_High humidity environment increases FBG by impairing the intestinal barrier.docx by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Image 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff by Songtao Li (186776)

“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”

Supplementary file 1_Gut microbiome and serum metabolome alterations in osteosarcoma patients.docx by Chao Li (145513)

“…This study aimed to characterize the gut microbiota and serum metabolite profiles in osteosarcoma patients, evaluate the diagnostic potential of gut microbiota and serum metabolites for osteosarcoma, and explore their correlations.</p>Methods<p>We collected 128 fecal and 181 serum samples from osteosarcoma patients, paired with matched healthy controls. 16S rRNA sequencing and untargeted metabolomics were applied to analyze gut microbiota and serum metabolism with significantly altered abundance in patients with osteosarcoma. …”

Data Sheet 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.pdf by Yali Han (4676677)

“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”

Supplementary Material for: Comprehensive Genetic Analysis Exploring Sedentary Lifestyle, Physical Activity, and Respiratory Diseases: A Bidirectional Mendelian Randomization with... by Wan W. (4013744)

“…Despite numerous studies, uncertainties and controversies regarding causal relationships persist. We utilized Mendelian randomization (MR) analysis, an advanced statistical tool, to further investigate causal links. …”