Table 1_Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells.xlsx by Joshua Flynn (2544523)

“…</p>Methods<p>This study utilised a targeted single-cell multi-omics approach to characterise peripheral blood mononuclear cell (PBMC) populations and their transcriptomic profiles in an Irish cohort of people with (i) sepsis and (ii) bacteraemia without sepsis (defined as clinically significant positive blood culture without sepsis as assessed by the Clinical Microbiology service).…”

The framework of this study. by Yin Yu (3139023)

“…The results show that (1) the landscape pattern changed visibly from 2000 to 2020, the comprehensive land-use dynamics increased from 8.53% to 9.66%, and the land use dynamics are greatest and change most dramatically on construction sites; (2) the landscape ecological risk level of the study area as a whole showed a declining trend, and 96.82% of the ecological risk plot index decreased, and the risk distribution was dominated by lower risk, medium risk and higher risk areas; (3) landscape ecological risk was spatially positively correlated across all time periods, and the spatial aggregation was gradually weakened, with the distribution of LH and HL areas dispersed and the distribution of HH and LL areas concentrated. …”

Data Sheet 2_Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells.docx by Joshua Flynn (2544523)

“…</p>Methods<p>This study utilised a targeted single-cell multi-omics approach to characterise peripheral blood mononuclear cell (PBMC) populations and their transcriptomic profiles in an Irish cohort of people with (i) sepsis and (ii) bacteraemia without sepsis (defined as clinically significant positive blood culture without sepsis as assessed by the Clinical Microbiology service).…”

Data Sheet 1_Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells.docx by Joshua Flynn (2544523)

“…</p>Methods<p>This study utilised a targeted single-cell multi-omics approach to characterise peripheral blood mononuclear cell (PBMC) populations and their transcriptomic profiles in an Irish cohort of people with (i) sepsis and (ii) bacteraemia without sepsis (defined as clinically significant positive blood culture without sepsis as assessed by the Clinical Microbiology service).…”

Synovial Fluid-Derived Exosomes from Osteoarthritis Patients Modulate Cell Surface Phenotypes of Monocytes and Cytokine Secretions by Nur Azira Mohd Noor (20457390)

“…<p>Exosomes can be found in the synovial fluid of inflamed knee joints, which play a significant role in osteoarthritis (OA) progression. …”

Image 1_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”

Table 1_Novel integrated approach modeling proanthocyanidins and bacteriophages to combat multidrug Salmonella Typhimurium in challenged broilers.docx by Hanan S. Al-Khalaifah (12864938)

“…Thus, we performed a comprehensive analysis of the combined impact of Salmonella bacteriophage (BP) and grape seed oligomeric pro-anthocyanidins (GSOPs) on growth performance, immune functions, antioxidant capacity, cecal microbiota, gut integrity, and S. …”

The impact of Ca²⁺ on the protective mechanisms of the photosystem under drought stress by Yanli Wei (1791124)

“…Transcriptomic analysis revealed a significant reduction in the expression of genes related to the PSI and PSII reaction centers, ATP synthesis, electron transport, and antenna proteins under drought stress. …”

Fertilization and herbivore exclusion promote more deterministic processes in plant community assembly on the Qinghai–Tibet Plateau by Wei Zhao (21458114)

“…The results showed that, compared to the control, species richness significantly decreased under fertilization, herbivore exclusion, and their combined treatment, with the greatest decline in species richness observed in the final year of the experiment. …”

Image 2_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.…”

Image 1_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.…”

Image 3_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.…”

Data Sheet 1_Soil microbiome dysbiosis and rhizosphere metabolic dysfunction drive continuous cropping obstacles of Codonopsis tangshen.docx by Dabing Xu (18961138)

“…However, their abundance decreased significantly under continuous cropping, ultimately disrupting soil carbon cycling. …”

Data Sheet 1_Peers are as persuasive as experts in reducing willingness to pay for sugary foods.pdf by Nina Arzumanyan (22759610)

“…</p>Results<p>All audio interventions significantly decreased participants’ WTP for sugar-containing products compared to sugar-free products. …”

Table 1_Dietary supplementation with soluble corn fiber improved fecal score, microbiota, and SCFAs in dogs.docx by Donghui Liang (8981447)

“…Microbial diversity analysis showed the addition of SCF to the diets increased the relative abundance of Bacteroidota and Blautia and decreased the relative abundance of Firmicutes, [Ruminococcus]_gnavus_group, and Prevotellaceae_Ga6A1_group; 1% SCF the relative abundance of Prevotella and Blautia (p < 0.05), and the content of acetic acid, valeric acid, and isobutyric acid (p < 0.05) and significantly decreased the content of butyric acid (p < 0.05).…”

Data Sheet 1_Mycorrhizal extraradical mycelium can reduce cadmium uptake by maize and cadmium leaching from contaminated soil: based on an in-growth core experiment.docx by Yijie Yang (2804824)

“…Moreover, the rotation treatment significantly altered the Cd forms in the soil solution and leachate, increasing the proportion of free Cd²⁺ by 0.8–2.1% and decreasing the proportions of CdSO₄(aq) and CdOH⁺ by 6.1–56.1% and 26.1–48.7%, respectively. …”

Data Sheet 1_Characteristics of gut microbiota in Penaeus vannamei shifted with elevated salinity.docx by Bo Wang (86769)

“…The alpha diversity of the gut bacterial community of shrimp decreased with salinity. Significant differences in the composition and abundance of the core gut bacterial taxa were observed among ponds with varying salinity, and only 13 shared core operational taxonomic units (OTUs) were identified; the abundance of potential opportunistic pathogens decreased significantly in hypersaline environments. …”

Data Sheet 1_N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder.pdf by Etna J. E. Engeli (20793524)

“…Cue reactivity and subsequent craving significantly elevate the risk of substance use, creating a pressing need for treatments that can help alleviate cravings. …”

Image 1_Emphysema-related mortality rates in the U.S. from 1999 to 2022.pdf by Alexandra Brown (225908)

“…</p>Discussion<p>Emphysema-related deaths in the United States decreased overall between 1999 and 2022, likely a result of a greater emphasis on health education concerning the significant dangers of smoking and policy changes that made cigarettes less accessible and less affordable, and more available access to resources and support networks.…”

Data Sheet 7_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The results show that (1) there are three stages, namely, compression, pore development, and post-peak failure, which promote the development and evolution of medium pore and macropores in lignite. (2) Under uniaxial compression, the permeability of the lignite sample shows a “V-shaped” trend, first decreasing and then increasing. …”