Docetaxel and quercetin-loaded lipid nanocarrier optimized by quality by design for glioblastoma therapy: a ligand-conjugated and therapeutic repurposing approach by Zufika Qamar (22259678)

“…Compared to non-conjugated NLC and (DTX-QUR) suspension (SUS), Tf-(DTX-QUR) NLC showed 3.6- and 5.8-fold decrease in IC₅₀, respectively. Cellular uptake studies demonstrated significantly (<i>***p < 0.001</i>) high internalization of Tf-conjugated NLC to U87-MG cells. …”

Table 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.docx by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Image 2_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Image 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Table1_Identification and expression profiling of neuropeptides and neuropeptide receptor genes in a natural enemy, Coccinella septempunctata.DOCX by ShunDa Han (19822464)

“…During diapause induction, the mRNA abundance of AKH was notably higher on the 10th day compared to non-diapause females, but decreased by the 20th day. In contrast, GPHA showed lower expression levels on the 5th day of diapause induction compared to non-diapause females, but increased significantly by the 15th and 20th days. …”

White-to-opaque switching frequencies of double TF heterozygotes in a <i>WOR1</i>(KR-to-G) strain background. by Collin Ganser (8924843)

“…<p><b>(A)</b> Genotypes of the strains used in <b>B + C</b>. …”

Table 2_Quantitative evaluation of IVL: based on the tunica media gypsum calcification model and a prospective animal study.doc by Zongwei Liu (3133743)

Table 1_Quantitative evaluation of IVL: based on the tunica media gypsum calcification model and a prospective animal study.doc by Zongwei Liu (3133743)

Supplementary file 1_Indirect regeneration of long-term callus cultures in gladiolus: a protocol for stable genetic fidelity.docx by Seyedehraziyeh Mousavimatin (21398525)

“…This medium led to an 80% decrease in the accumulation of phenolic compounds across all cultivars in comparison to the control. …”

Image_1_The causal effects of dietary component intake and blood metabolites on risk of delirium: a Mendelian randomization study.pdf by Qian Zhu (191342)

Table_1_The causal effects of dietary component intake and blood metabolites on risk of delirium: a Mendelian randomization study.xlsx by Qian Zhu (191342)

Analysis of biases in amplicon coverage across samples sequenced with diverse Ampliseq-based protocols (DDD/IDI/III – corresponds to variations of PCR mix1 (I/D), ligase/buffer (I/... by P.A. Shatalov (21485215)

“…<p><b>(A)</b> – heatmap of amplicon coverage (% of average coverage) across samples demonstrates significant variation in per-sample set of dropped out (10% of average sample coverage) amplicons depending on <b>i)</b> PCR mix 2 used <b>ii)</b> Digest Mix used. …”

Data Sheet 1_Efficacy of music intervention on pain and anxiety in patients undergoing cataract surgery: a systematic review and meta-analysis.docx by Lanzhu Su (21570704)

“…</p>Results<p>Eighteen studies with 2,262 participants were included. Music therapy significantly reduced anxiety levels, as demonstrated by a notable decrease in Visual Analog Scale (VAS) anxiety scores (SMD = -7.10, 95% CI: -12.25 to -1.95) and State-Trait Anxiety Inventory (STAI) scores (SMD = -1.26, 95% CI: -1.85 to -0.66). …”

Data Sheet 1_The efficacy and safety of panax quinquefolius saponin for heart failure: a systematic review and meta-analysis.pdf by Jing Wang (6206297)

“…</p>Results<p>This study included nine RCTs involving a total of 952 patients with HF. The results of a meta-analysis under a random-effects model showed that adjuvant PQS therapy significantly increased LVEF (MD = 6.23, 95% CI [4.35, 8.12], P < 0.00001), 6MWTD (MD = 25.26, 95% CI [8.23, 42.30], P = 0.004), and decreased BNP/NT-pro-BNP (MD = −187.94, 95% CI [−267.20, −108.67], P < 0.00001), LVEDV (MD = −22.83, 95% CI [−42.79, −2.87], P = 0.02), LVEDD (MD = −4.76, 95% CI [−5.77, −3.74], P < 0.00001), and LVESV (MD = −11.86, 95% CI [−19.89, −3.83], P = 0.004) in patients with HF.…”

Burden trends and risk factors for prostate cancer from 1990 to 2021: a systematic analysis of the Global Burden of Disease Study 2021 by Yuan Xu (161775)

“…PCa was more common in regions with a high SDI. Mortality was the highest in regions with a low SDI. …”

Image 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.pdf by Zhanyi Yang (5142182)

“…Furthermore, MORC4 knockdown led to an increased expression of genes associated with cholesterol synthesis (HMGCR), varying levels of genes implicated in the uptake of fatty acids and cholesterol (PCSK9, PLTP, CD36), and a decrease in the levels of genes involved in triglyceride hydrolysis (APOC2, APOA4, LIPG, LIPA). …”

Table 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.xlsx by Zhanyi Yang (5142182)

“…Furthermore, MORC4 knockdown led to an increased expression of genes associated with cholesterol synthesis (HMGCR), varying levels of genes implicated in the uptake of fatty acids and cholesterol (PCSK9, PLTP, CD36), and a decrease in the levels of genes involved in triglyceride hydrolysis (APOC2, APOA4, LIPG, LIPA). …”

Relationship between purposeful rumination and post-traumatic growth of college students who experienced childhood trauma: a regulated intermediary model by Sanglin Zhao (20599835)

“…Results: Correlation analysis showed that purposive rumination, positive coping and post-traumatic growth were significantly correlated. Regression analysis showed that purposive rumination had a significant direct effect on post-traumatic growth (β=0.148, P<0.001) . …”

Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx by Vanessa I. T. Zwaans (22163257)

“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”

Ambulatory modeling of vocal hyperfunction (Parra et al., 2025) by Jesús A. Parra (20677929)

“…Higher DPI values, reflecting more severe PVH, were associated with increased mean LCA activation and decreased LCA variability, along with decreased mean CT activation and increased median PS. …”