Table 1_Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic revie... حسب Zhenzhen Zhao (782550)

"…A significant association was found between decreased serum BDNF concentrations and cognitive impairment in PD (SMD = −1.035; 95% CI [−1.340, −0.730]; P < 0.001). …"

Dataset in. CSV. حسب Kare Chawicha Debessa (20660605)

"…Adjusted Odds Ratios (AOR) with 95% Confidence Intervals (CI) were reported, with statistical significance set at p < 0.05.</p><p>Findings</p><p>Among the 845 women sampled, 835 participated in the interviews with a response rate of 98.8%. …"

DataSheet1_Glucose-lowering medications and glucose levels as the major determinants of progression of carotid atherosclerosis in middle-aged adults and elders: a community-based p... حسب Chao-Liang Chou (2854052)

"…</p>Conclusion<p>We found that more than 50% of CA-positive subjects had CAP in 4 years and higher FPG significantly increased and GLM significantly decreased the risks of CAP. …"

Data Sheet 1_Induction immunochemotherapy followed by definitive chemoradiotherapy and consolidation immunotherapy for unresectable stage III non-small cell lung cancer: a multi-in... حسب Zhixue Fu (7540256)

"…The I-CRT-I group showed a significant improvement in OS compared with the CRT-I group (p=0.004). …"

Data Sheet 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021... حسب Lili Deng (152262)

"…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …"

Data Sheet 2_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021... حسب Lili Deng (152262)

"…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …"

Table 1_Weizmannia coagulans BC99 regulates oxidative stress and serum metabolic pathways to improve allergic rhinitis: a randomized, double-blind, placebo-controlled trial.docx حسب Xuan Li (137217)

"…Furthermore, BC99 supplementation significantly decreased serum IgA, complement C3, EOS, and MDA levels (p < 0.05) while enhancing antioxidant capacity (increased GSH, stabilized SOD). …"

Data Sheet 1_A glycogen derived from sea urchin-Strongylocentyotus internedius shifts macrophages to the M1 phenotype and enhances the anti-pancreatic cancer activity of gemcitabin... حسب Zhenzhen Deng (3707608)

"…In prior study, we isolated a polysaccharide from sea urchin-Strongylocentyotus internedius, which was identified as a high molecular weight, highly branched glycogen (MSGA). …"

The number of sampling cercariae and snails affected the coverage of alleles. حسب Juan Long (4017317)

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx حسب Juanzhao Cao (22651742)

Data Sheet 1_Aperiodic brain activity changes in patients with stroke following virtual reality-based upper limb robotic rehabilitation: a pilot Randomized Controlled Trial.docx حسب Maria Cristina Mauro (22449604)

"…These SEI changes mirrored motor recovery, suggesting that it may represent a useful biomarker to track localized neural mechanisms of functional improvement after stroke. …"

Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf حسب Warda Ahmed (5593586)

"…Background<p>Early coronary angiography (CAG) in post-cardiac arrest patients without ST-segment elevation is a topic of debate. This meta-analysis aimed to assess its impact on outcomes.…"

Data Sheet 1_Serum stromal cell-derived factor 1α as a prognostic indicator in elderly patients with acute myeloid leukemia receiving CAG-based chemotherapy.docx حسب Zhenzhen Wang (250368)

"…Background<p>Stromal-cell-derived factor 1 (SDF-1) plays a crucial role in hematopoiesis and has been implicated in acute myeloid leukemia (AML) pathogenesis. …"

Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx حسب Wenjia Ge (22687361)

"…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…"

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX حسب Cataldo Martucci (3117069)

"…In mice exposed to tobacco smoke (TS), CHF6297, administered intranasally (i.n.) for 4 days at 0.03 or 0.3 mg/kg, dose-dependently inhibited the corticosteroid-resistant TS-induced neutrophil influx in the BALF. In a murine house dust mite (HDM) model of asthma exacerbated by influenza virus A (IAV) (H3N3), CHF6297 (0.1 mg/kg, i.n.) significantly decreased airway neutrophilia compared to vehicle-treated IAV/HDM-challenged mice. …"

Differentially used transcripts (DUT) for T1R and LEP groups suggest dysregulation of inflammatory circuitry in T1R. حسب Wilian Correa-Macedo (11813183)

"…They are shown in white for the group where the response was not significant and colored for the group where the response was significant. …"

Supplementary file 1_Global, regional, and national burden of iodine deficiency for women of reproductive age, 1990–2021: a systematic analysis based on the Global Burden of Diseas... حسب Taotao Wang (115296)

"…Iodine deficiency among WRA remains a significant public health issue. It is crucial to prioritize the development of effective, targeted strategies and implement monitoring mechanisms to enhance the iodine levels among WRA.…"

Treatment consequence and adverse events of cyclin-dependent kinase 4/6 inhibitors on patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic... حسب Hsiang-Ying Wu (22212274)

"…</p> <p>Eleven clinical trials published between 2015 and 2022 were included in our meta-analysis, with a total of 5572 eligible patients. This meta-analysis found that HR(+)/HER2(−) metastatic breast cancer treated with CDK4/6 inhibitors plus endocrine therapy can significantly improve progression-free survival(PFS) (HR: 0.55; <i>p</i> < 0.001), overall survival (OS) (HR: 0.79; <i>p</i> < 0.001), objective response rate (RR = 1.50; <i>p</i> < 0.001), clinical benefit rate (RR = 1.18; <i>p</i> < 0.001) and decrease progressive disease rate (RR = 0.49; <i>p</i> < 0.001). …"

Data Sheet 1_Global burden, trends and inequalities of maternal hypertensive disorders among reproductive-age women of advanced maternal age, 1990–2021: a population-based study.pd... حسب Xuanyu Zhao (5881895)

"…Background<p>Maternal hypertensive disorders (MHD) are leading causes of maternal morbidity and mortality worldwide, particularly among reproductive-age women of advanced maternal age (AMA), representing a significant global public health challenge.</p>Objective<p>This study aimed to analyze the global trends, inequalities, and disparities in the burden of MHD among reproductive-age AMA women from 1990 to 2021.…"

Image 1_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff حسب Yanqin Li (499034)

"…Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …"