Image 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Data Sheet 1_Exploring AI-personalized visualization of the safe place in virtual reality versus imagination of the safe place for stress, burnout, and relaxation in psychotherapis... by Viktoria Wollweber (22651739)

“…Burnout and stress did not significantly decrease over time and VR did not yield significantly greater effects on all outcomes. …”

Table 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.docx by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Supplementary file 1_Clinical application of combined anticoagulation therapy in anti-MDA5 antibody-positive associated interstitial lung disease-a retrospective study.docx by Ting Zhang (102583)

“…Meanwhile, C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH), and Creatine Kinase (CK) levels decreased significantly. Also, the incidence of complications and acute exacerbation was lower in the combined group (P < 0.05). …”

Table 1_Nanocarrier-mediated RNAi of CYP9A306 and CYB5R enhances susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx by Farman Ullah (783297)

“…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9A306 genes significantly reduced their expression levels. …”

Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX by Mingming Zhao (760369)

“…Nineteen identified metabolites, including five organic acids, four short-chain fatty acids, four amino acids, three fatty acids, and three benzenoids, differed significantly among the three groups, showing a strong association with VPA-induced hepatotoxicity. …”

Table 1_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx by Shengbo Yang (295144)

“…</p>Results<p>Higher MIND scores were associated with reduced steatosis as measured by HSI and CAP, lower fibrosis indicated by the FIB-4 index, improved insulin sensitivity reflected by lower HOMA-IR values, decreased liver enzyme levels, and a more favorable lipid profile. …”

Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx by Shengbo Yang (295144)

“…</p>Results<p>Higher MIND scores were associated with reduced steatosis as measured by HSI and CAP, lower fibrosis indicated by the FIB-4 index, improved insulin sensitivity reflected by lower HOMA-IR values, decreased liver enzyme levels, and a more favorable lipid profile. …”

Supplementary Material for: Effect of gonadotropin dose reduction during COH on progesterone levels and embryo outcomes in women undergoing IVF/ICSI-ET with GnRH-A protocol by figshare admin karger (2628495)

“…The proportion of patients with P ≥ 1.5 ng/ml was significantly lower in the gonadotropin dose reduction group compared to the control group (22.7% vs. 29.9%, P=0.003).Multivariable logistic regression indicated that dose reduction decreased the risk of progesterone elevation [OR=0.535, 95% CI: 0.404-0.709]. …”

Data Sheet 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf by Yaser Shabanpour (13247160)

“…<p>Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation of polyunsaturated fatty acids (PUFAs). …”

DataSheet2_Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model.xlsx by Angelo Massaro (11939127)

“…The crypts possessed a basal stem cell niche populated with proliferative cells and a differentiated, nondividing cell zone at the luminal crypt end. …”

DataSheet1_Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model.docx by Angelo Massaro (11939127)

“…The crypts possessed a basal stem cell niche populated with proliferative cells and a differentiated, nondividing cell zone at the luminal crypt end. …”

Table 1_Association of serum chemokine (C–C motif) 21 and receptor (C–C motif) 7 with Hashimoto’s thyroiditis——a preliminary clinical investigation.docx by Xiaoting Gui (22516922)

“…</p>Results<p>Compared with the healthy control group, the Hashimoto’s thyroiditis group had significantly increased serum CCL21 [154.92 (147.01, 165.34) vs 123.74 (118.02,129.22), p<0.001] and CCR7 [19.15 (18.19, 19.71) vs 16.47 (15.88, 17.14), p<0.001], decreased free triiodothyronine, and increased thyroid stimulating hormone, TgAb, and TPOAb. …”

Supplementary file 1_An expert patient program for people living with multiple sclerosis improves knowledge and empowerment: a pre-test, post-test multicenter implementation study.... by Miguel Ángel Robles-Sánchez (21211703)

“…Lifestyle habits remained mostly unchanged, except for medication self-management and diet, whereas visits to nurses and other professionals in MS units significantly decreased. Physical health composite scores in the MS quality of life-54 questionnaire decreased, while the mental health composite scores remained unchanged. …”

Image 1_Double-lumen tubes verus single-lumen tube in patients undergoing minimally invasive cardiac surgery: a randomised, controlled clinical trial.pdf by Zhenzhong Wang (407028)

“…</p>Conclusions<p>Two-lung ventilation with single-lumen tube is easy to perform, significantly increases oxygenation, and decreases the incidence of postoperative complications and airway injuries. …”

Data Sheet 1_Efficacy of different pharmaceutical forms of Curcuma longa or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and m... by Pedro de Padua G. Amatto (20981201)

“…OM incidence decreased by 6% overall, with a notable 37%-reduction observed in patients using curcumin-containing mouthwash during radiotherapy alone. …”

Data Sheet 1_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx by Alexia Giovanazzi (16816139)

“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. …”

Table 1_Associations between systemic inflammatory indices and the risk of renal function decline in patients with type 2 diabetes mellitus: a retrospective cohort study.docx by Zhi Shang (4849129)

“…The ROC curves showed that the SIRI was better than other two indices at predicting renal function decline.</p>Conclusion<p>A significantly positive association was shown between systemic inflammatory indices and the risk of renal function decline in T2DM patients. …”

Data Sheet 2_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx by Alexia Giovanazzi (16816139)

“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. …”

Data Sheet 1_Analysis of lymphocytic leukemia trends among gender, race, age, and regional groups in the U.S. between 1999-2022: a CDC-WONDER database study.docx by Shannon Blee (15251230)

“…Statistical significance was set at p ≤0.05.</p>Results<p>Between 1999 and 2022, there was a decrease in overall mortality rates up until 2018, followed by an increase from 2018 to 2022. …”