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10661
Table 7_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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10662
Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents
Published 2025“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”
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10663
Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents
Published 2025“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”
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10664
Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents
Published 2025“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”
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10665
Supplementary Table 1–9.
Published 2025“…Furthermore, a decrease in total cholesterol exhibited a causal effect on sepsis in multivariable MR (OR 0.779, 95% CI 0.642–0.944; P = 0.01). …”
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10666
STROBE-MR checklist.
Published 2025“…Furthermore, a decrease in total cholesterol exhibited a causal effect on sepsis in multivariable MR (OR 0.779, 95% CI 0.642–0.944; P = 0.01). …”
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10667
Instrumental Variables details of lipids.
Published 2025“…Furthermore, a decrease in total cholesterol exhibited a causal effect on sepsis in multivariable MR (OR 0.779, 95% CI 0.642–0.944; P = 0.01). …”
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10668
Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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10669
Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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10670
Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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10671
Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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10672
Data Sheet 1_Retroperitoneal fibrosis in presence of autoimmune coagulation factor XIII deficiency result in recurrent critical post-operative hemorrhage: a case report and molecul...
Published 2025“…We investigated the potential involvement of IgG4-related disease and the effects of IgG4 on coagulation Factor XIII using an in vitro system, and it was demonstrated that both IgG1 and IgG4 recognized the A subunit of coagulation Factor XIII. The purified IgG antibody samples containing IgG1 and IgG4 were shown to significantly reduce the function of coagulation Factor XIII derived from healthy individuals. …”
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10673
Table 1_Does screening mode matter? A repeated cross-sectional study of computer self-administered vs. clinician-administered screening of youth substance use in pediatric primary...
Published 2025“…Patients responded to the Car, Relax, Alone, Forget, Family/Friends, and Trouble (CRAFFT), a well-validated adolescent substance use screening tool that measures past-12-month alcohol, cannabis, and other substance use (“anything else to get high”). …”
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10674
Data Sheet 1_An alternative structured weight management protocol to rapid weight loss in mixed martial arts: a prospective interventional study of pre-competition weight managemen...
Published 2025“…For MMA athletes, adhering to an evidence-based Weight Management Protocol (WMP), targeting a 10% body weight reduction within 7 days prior to weigh-in, poses a significant challenge. …”
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10675
Controller parameters of two control methods.
Published 2025“…Numerical simulations confirm the superiority of the proposed control method, with results showing an reduction in settling time and a decrease in peak overshoot compared to conventional PD control. …”
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10676
The diagram of flexible spacecraft system.
Published 2025“…Numerical simulations confirm the superiority of the proposed control method, with results showing an reduction in settling time and a decrease in peak overshoot compared to conventional PD control. …”
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10677
Data Sheet 1_Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and athe...
Published 2025“…</p>Conclusion<p>The use of STS in patients with AS and ASCVD appeared to significantly decrease levels of pro-inflammatory cytokines, adhesion molecules, and chemokines.…”
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10678
Supplementary Material for: Treatment of plaque psoriasis with guselkumab reduces systemic inflammatory burden as measured by neutrophil/lymphocyte ratio, platelet/lymphocyte ratio...
Published 2025“…In VOYAGE I, NLR (p=0.011), PLR (p=0.015) and MLR (p=0.004) decreased significantly following 16 weeks of guselkumab treatment vs. placebo. …”
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10679
Smart spot and smart triage platform.
Published 2025“…The inpatient mortality rate decreased from 5.1% in August 2018 to 2.6% in October 2023, with a significant increase in the number of cases with comparable illness severity.…”
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10680
HICH patient demographics during QI intervention.
Published 2025“…The inpatient mortality rate decreased from 5.1% in August 2018 to 2.6% in October 2023, with a significant increase in the number of cases with comparable illness severity.…”