Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in S4 Table) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE. A subset of D0 monocyte & NK cocultures was also treated with the TGFβ1 inhibitor LY (D0 LY), and a subset of D90 cocultures were supplemented with rhTGFβ1. The graph shows individual data points, means and p values calculated by Friedman test for repeated measures with FDR correction. LY treatment of cells collected on D0 significantly increased their activation to levels similar to D90. Conversely, treatment of D90 cells with rhTGFβ1 significantly decreased their activation to levels similar to D0. by Michael J. Johnson (5818168)

“…Conversely, treatment of D90 cells with rhTGFβ1 significantly decreased their activation to levels similar to D0.…”

Image 2_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Results<p>G. vaginalis inoculated mice infected with HSV-2 had significantly decreased survival rates, increased pathology, and higher viral titers than PBS and L. crispatus inoculated mice. …”

Image 5_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Results<p>G. vaginalis inoculated mice infected with HSV-2 had significantly decreased survival rates, increased pathology, and higher viral titers than PBS and L. crispatus inoculated mice. …”

Image 3_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Results<p>G. vaginalis inoculated mice infected with HSV-2 had significantly decreased survival rates, increased pathology, and higher viral titers than PBS and L. crispatus inoculated mice. …”

Image 1_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Results<p>G. vaginalis inoculated mice infected with HSV-2 had significantly decreased survival rates, increased pathology, and higher viral titers than PBS and L. crispatus inoculated mice. …”

Image 4_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Results<p>G. vaginalis inoculated mice infected with HSV-2 had significantly decreased survival rates, increased pathology, and higher viral titers than PBS and L. crispatus inoculated mice. …”

Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

A pulse of TNF-alpha halts the growth of <i>L</i>. <i>intracellularis</i> in-vitro. by Huan W. Yang (19746645)

Mucosal turnover in the duodenum and the jejunum following different diets at T1 and T2 post-weaning periods. by Marcella Massimini (5678543)

“…<p>IHC images (top row) showing a significant decrease in the number of cleaved-caspase-3 positive cells observed at T2 in the jejunum following PRE/PRO supplemented diet (B_20x) and an increase in Ki-67 positive cells following PRO supplementation (D_20x), compared to CTR (A and C, respectively_20x). …”

Baseline and Post-Treatment Myocardial Perfusion Defects Expressed as a Percentage of the Total Left Ventricular Surface Area in Each Experimental Group. by Káryta Suely Macêdo Martins (22404155)

A path analysis model of the relationship between various scenario elements and traffic scenarios. by Chengmin Zhou (14554562)

Maps of median projected λ_<i>S</i> (a) and <i>R</i>₀ (b) across 1st-level sub-national administrative regions in selected South American countries. by Keith Fraser (1868587)

Bidimensional High-Low Frequency (HF, LF) plane representation of the interaction among Phase and High-Low Authoritativeness Groups_.: In the Low Authority (LA) group the... by David Vagni (8060432)

Data Sheet 1_Prognostic value of left atrial strain in significant aortic valve disease: a systematic review and meta-analysis.pdf by Na Chen (153323)

“…Background<p>Previous studies on aortic valve disease have mainly focused on the left ventricle, but increasing evidence suggests that left atrial strain also has prognostic value in significant aortic valve disease.</p>Objective<p>To systematically evaluate the prognostic value of left atrial strain in significant aortic valve disease.…”

Median ± IQR <i>M. plutonius</i> bacterial load (CFU/bee) of newly emerged summer worker bees inoculated with 1 × 10⁷ CFU/bee <i>M. plutonius</i> 2019BC1 and/or treated... by Midhun Sebastian Jose (19336846)

Lifespan of a single <i>T. utriculata</i> rosette. by Alexandra M. Campbell (3284094)

Decomposition analysis of the changes in prevalence (A), DALYs (B), and mortality (C) rates of IBD among women across global, 5 SDI and 21 GBD regions. by Jiefeng Zhao (9090305)

Percent viability and cytotoxicity of NHBE cells are significantly altered by PAA exposure. by Ellie S. Burns (21246537)

“…Percent viability significantly decreased with PAA concentration and between recovery times compared to controls. …”

Relative abundance (%) of the major endophytic bacterial phyla/classes identified in the 29 accessions of <i>Synsepalum dulcificum</i> comparing the roots and leaves (A), the pheno... by Rabiath F. R. Adigoun (14189090)

a, Anti-correlation of gene expression between <i>dmdR1</i> and its predicted regulon. Left: Pearson correlation coefficients (PCCs) between <i>dmdR1</i> and all genes with a DmdR1 position weight matrix (PWM) score greater than 15 in their regulatory region. The vertical dashed line marks the refined PWM score threshold of 22.875. The horizontal dotted lines mark PCC = ±0.43, corresponding to an adjusted <i>p</i>-value of 0.05. Right: Target genes immediately downstream of a predicted DmdR1 binding site, ordered by decreasing PWM score.... by Hannah E. Augustijn (10773096)

“…Right: Target genes immediately downstream of a predicted DmdR1 binding site, ordered by decreasing PWM score. …”