Additional file 11 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma حسب Benjamin Lin (120565)

"…Genes were categorized as upregulated “up” or downregulated “down” by K-means clustering. Of these categorized genes, 980 and 844 are significantly (DESeq2 FDR < 0.05 and LFC > 1) increased and decreased after treatment with either drug (C). …"

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing حسب Noora Kantola (14263490)

"…On the contrary, increased snow depth decreased C source strength inside the exclusion offsetting the difference between reindeer grazing treatments. …"

Data Sheet 1_A multimodal approach for establishing ACTL6A and ERCC1 as chemoresistance genes in locally advanced head and neck cancer.docx حسب Raushan Kumar Chaudhary (15664043)

"…</p>Results<p>A total of 77 LAHNC patients were enrolled in this study, of which 96.1% were men and 3.9% were women with a mean age of 52.88 ± 9.68 years. The median expressions of ERCC1 were significantly increased (p < 0.001) after 50% (0.19) and 100% CRT (0.23) compared to the baseline value (0.14), whereas ACTL6A expression decreased from 4.77 to 3.87 after 50% CRT (p < 0.05) and increased to 5.43 after 100% CRT. …"

A Proposal for Implementation of Multi-Factor Authentication (MFA) System for Enhanced Security By Stephen Mikah Makoshi حسب Stephen Mikah Makoshi (20998469)

"…<b>Reduced Reliance on Passwords</b>: Decreased risk of security incidents related to passwords.…"

Data Sheet 1_Listening to mom in the neonatal intensive care unit: a randomized trial of increased maternal speech exposure on white matter connectivity in infants born preterm.pdf حسب Katherine E. Travis (6680396)

"…We hypothesized that neonates randomized to the T-group would show evidence for increased maturation within the arcuate, indexed as decreased MD and increased FA and R1, compared to neonates in the C-group.…"

<i>ADH7, FABP5, ALDH1A1, CRABP-2, PPARγ</i> and <i>VEGFA</i> mRNA and ADH7, FABP5, CRABP-2, PPARγ and VEGFA protein levels in limbal stromal cells (LSCs) and aniridia limbal stroma... حسب Shuailin Li (11907158)

"…Furthermore, 0.078 and 0.313 μg/mL travoprost treatment significantly decreased ADH7 protein levels in LSCs (p = 0.039; p < 0.001) and 0.313 μg/mL travoprost treatment significantly increased ADH7 protein levels in AN-LSCs, compared to their untreated controls (p = 0.039) <b>(B, C)</b>. …"

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. حسب Weiran Huang (8934899)

"…<p>(A) OVD injections led to IOP increase, with values presented as means ± SD. IOP decreased 6 hours post-injection and by day 1 had returned to near baseline levels. …"

Data Sheet 1_The effect of vagus nerve stimulation on heart rate and respiration rate and their impact on seizure susceptibility in anaesthetized rats under pentylenetetrazol.pdf حسب Javier Chávez Cerda (20913026)

"…Results indicate that the stimulation significantly decreased the heart rate below baseline levels for standard VNS (−120.0 ± 69.1 bpm) and breathing-synchronized VNS (−84.9 ± 61.0 bpm), overcoming the heart rate increasing effect of PTZ infusion observed in the sham VNS (+79.2 ± 35.5 bpm), and there was no recovery during OFF periods. …"

Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx حسب Shenghua Lu (20762612)

"…Regarding neurological function, the BCP combination group significantly increased the Glasgow Coma Scale score (MD = 1.86, 95% CI 1.17 to 2.56, p < 0.00001) and decreased the National Institutes of Health Stroke Scale score (MD = −2.17, 95% CI −3.35 to −0.99, p = 0.0003). …"

Data Sheet 1_Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors.docx حسب Monika Marko (7926311)

"…Education resulted in equalizing the level of correctness of inhalation, which was similarly high for each type of device. This means that after education, all inhalers have similar difficulty levels in performing the correct inhalation technique. …"

Table 2_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx حسب Jae-Chang Sim (22335904)

"…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…"

Table 1_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx حسب Jae-Chang Sim (22335904)

"…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…"

Differential neural dynamics in the GNP model incorporating electrodiffusion and ion concentration changes. حسب Zichao Liu (4591993)

"…(f) The harmonic means of intramembrane potassium and chloride concentrations increase, whereas for sodium, it decreases during neural activity. …"

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies حسب Shazia Sofi (17764488)

"…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …"

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx حسب Juan Liu (6492)

"…</p>Methods<p>In this study, we evaluated the synergism of tigecycline combining with other antibiotics as a means of overcoming the tet(X)-mediated resistance in Acinetobacter spp. …"

Extraction time and mustard concentration for extraction of aquatic oligochaetes by using wet funnel حسب Satoshi Kaneda (571209)

"…In Exp.S1.1, under continuous extraction, efficiency increased from 2 h to 5 h but was greater over 2 h than over 24 h using different soil samples in Exp. …"

Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx حسب Reema Priyanka Suram (22399759)

"…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …"

Data Sheet 1_Disease burden of tuberculosis in China from 1990 to 2021 and its prediction to 2036.docx حسب Rong Sun (532754)

"…</p>Conclusion<p>TB burden in China has decreased significantly overall in the past years. …"

Heterotrophic cell growth and dry cell yield of <i>Rhodovulum sulfidophilum</i> in artificial seawater (ASW) based growth medium of different salinities, wherein 100% corresponds t... حسب Shamitha Rao Morey-Yagi (19779981)

"…Asterisks indicate significant differences between 100% and decreasing concentrations of ASW tested using one-way ANOVA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">Figs 1b</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">1c</a>) or two-way ANOVA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">Fig 1a</a>), and the Dunnett’s multiple comparison test (GraphPad Prism 9); * p < 0.05, ** p < 0.01, and *** p < 0.001.…"

Impairing lipolysis in <i>An</i>. <i>gambiae</i> females induces severe embryonic lethality. حسب Maurice A. Itoe (9930475)

"…(F, G) Injection of dsAg<i>LSD</i>1 (F) significantly reduces the number of eggs laid and (G) severely decreases survival rates (Mann–Whitney test). …"