Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Volcano plot on differential expression. by Bingshuo Shi (21485387)

“…The findings revealed that 5558 genes in total were significantly altered during diapause, with pyruvate kinase (PK), trehalose synthase (TPS), superoxide dismutase (SOD), citrate synthase (CS), and 20-hydroxyecdysone (20E) showing significant decreases. …”

Dose-response curve of the activity of chitosan solution (A), blank chitosan-TPP nanoparticles (B), AmB loaded chitosan-TPP nanoparticles (C) and AmB solution (pure) (D) against L. by Alaa Riezk (7037297)

Organic solvent exposure causes defects in salt chemotaxis learning. by Masahiro Tomioka (430683)

Critical Role of Voltage Application Points in “Analog” and “Digital” Electrospray Ionization Mass Spectrometry by Min-Min Hung (21096009)

“…We also show that a single-polarity square AC waveform can be applied to the union or sample reservoir electrode, and if its frequency is sufficiently high, it has a similar effect as decreasing DC voltage, allowing for digital control of electrospray with square waves (by varying duty cycle). …”

Critical Role of Voltage Application Points in “Analog” and “Digital” Electrospray Ionization Mass Spectrometry by Min-Min Hung (21096009)

“…We also show that a single-polarity square AC waveform can be applied to the union or sample reservoir electrode, and if its frequency is sufficiently high, it has a similar effect as decreasing DC voltage, allowing for digital control of electrospray with square waves (by varying duty cycle). …”

Effects of clonal integration and <i>Bacillus subtilis</i> on ramet number (A, E, I), total stolon length (B, F, J), specific stolon length (C, G, K), and root-shoot ratio (D, H, L... by Bing-Nan Zhao (21553401)

The (A) logistic regression model (LRM) and (B) random forest model (RFM) with only conservation scores as independent variables (orange, yellow) show decreased model fitting metri... by Bushra Haque (20513785)

Refractive error, spectacle wear, and referrals among public and private school children based on the AAPOS 2021 referral criteria. by Zahi Wehbi (14863016)

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Referral rate and rates of different refractive errors according to the different referral criteria. by Zahi Wehbi (14863016)

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Demographics of all study participants (n = 308 students; 616 eyes). by Zahi Wehbi (14863016)

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The sets of referral criteria applied in the study. by Zahi Wehbi (14863016)

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Graphs of surface roughness values of test specimens after testing with varying concentrations across different particle size groups (a) Ra, Rq (b) Rz (c) Sa, Sq (d) Sz, Sv. by Yang Li (7082)

The experimental technology combining a fluid shear stress experimental system with Atomic Force Microscopy (AFM). by Xinyao Zhao (5824427)

Primer Sequence expression for VEGF-A and FGF2. by Yashwanth Elumalai (21743452)

“…Dynamic light scattering showed a significant reduction in the improved particle size (PDI decreased from 0.863 to 0.173) by nano-formulation from 559 nm to 220 nm. …”

(a) Convex, triangular, and concave geometry at a constant vertex angle. by Amirhossein Favakeh (21417884)