Data Sheet 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.pdf by Lei Xiang (528500)

“…</p>Results<p>ORes significantly reduces breast cancer cell viability and proliferation in a concentration-dependent manner, with IC₅₀ values of 104.8 μM, 150.2 μM, and 143.6 μM in MDA-MB-231, BT-549, and 4T1 cells, respectively. …”

Data Sheet 1_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.... by Yuxuan Zhang (1425721)

“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”

A reduced expression level of PfATP2-HA does not affect the resting pH_cyt in <i>P. falciparum</i> parasites or pH_cyt dysregulation by MMV665794 or MMV007224. by Deyun Qiu (8871143)

“…Two-way ANOVAs performed with the data shown in Panels <b>F</b> and <b>I</b> revealed a significant effect of the concentration of the MMV compound on the rate of pH_cyt decrease (<i>P</i> ≤ 0.04) but no significant effect of PfATP2-HA knockdown (<i>P</i> ≥ 0.5).…”

Image 2_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... by Yangtian Jiao (21725018)

“…Decomposition analysis highlighted the role of epidemiological improvements, balanced by the impacts of population growth and aging. Projections indicate a continued global decline, with a 43.81% reduction in the ASIR and a 62.92% decline in the age-standardized DALY rate by 2036.…”

Image 3_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... by Yangtian Jiao (21725018)

“…Decomposition analysis highlighted the role of epidemiological improvements, balanced by the impacts of population growth and aging. Projections indicate a continued global decline, with a 43.81% reduction in the ASIR and a 62.92% decline in the age-standardized DALY rate by 2036.…”

Image 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... by Yangtian Jiao (21725018)

“…Decomposition analysis highlighted the role of epidemiological improvements, balanced by the impacts of population growth and aging. Projections indicate a continued global decline, with a 43.81% reduction in the ASIR and a 62.92% decline in the age-standardized DALY rate by 2036.…”

Table 1_Global, regional, and national burdens of rheumatoid arthritis among people aged 60 years and older from 1990 to 2021: a trend analysis for the Global Burden of Disease Stu... by Qin-Yi Su (14188151)

“…Background<p>Rheumatoid arthritis (RA) poses a significant global health burden, especially among individuals aged 60 and older. …”

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... by Ying Feng (151159)

“…In contrast, metabolic disease burden was significantly elevated in postmenopausal women, exhibiting a pattern distinct from that of PCOS.…”

The efficacy and safety of Fluticasone Furoate/Umeclidinium/vilanterol (FF/UMEC/VI) on cough symptoms in adult patients with asthma, a randomized double-blind, placebo-controlled,... by Etsuko Tagaya (17601425)

“…The ACQ-5 scores showed a greater decrease in the FF/UMEC/VI group than in the placebo group. …”

Table 1_Inflammatory parameters mediates the relationship between dietary index for gut microbiota and frailty in middle-aged and older adults in the United States: findings from a... by Qijiang Yang (21096683)

“…Background<p>Frailty is a prevalent geriatric syndrome marked by diminished physiological reserves and heightened vulnerability to stressors, leading to adverse health outcomes and imposing significant economic burdens on healthcare systems.…”

Decision-maker informed optimal policy design. by Hongru Du (4640212)

Geometric interpretation and data visualisation equivalent describing the DI algorithmic pipeline. by Borjan Milinkovic (21349908)

The sequence for qPCR primers and shRNA. by Xiaoming Liu (47653)

“…<div><p>Chronic kidney disease (CKD) is a global health issue that significantly threatens human health, with its incidence increasing annually. …”

Data Sheet 1_Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis... by Yining Lu (6980597)

“…Compared with CON, LV-HIIT with reduced intensity and extended interval duration significantly improved fasting glucose (FPG) (mean difference (MD) in mg/dL=-16.63; 95% confidence interval (CI): -25.30 to -7.96; p<0.001) and HbA1c (MD=-0.70; 95% CI: -1.10 to -0.29; p<0.001). …”

Data Sheet 1_Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on... by Rui Yang (293531)

“…During dynamic activities, muscle fatigue was exacerbated in the abnormal curvature group: during extension, the left UT showed significantly decreased MPF (p < 0.01) and MF (p < 0.05); during flexion, the left SCM exhibited significantly increased MPFs (p < 0.05) and MFs (p < 0.01). …”

Data Sheet 1_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4⁺CD25^low and CD8⁺CD25^low) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4⁺CD25^high and CD8⁺CD25^high) function. …”

Data Sheet 2_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4⁺CD25^low and CD8⁺CD25^low) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4⁺CD25^high and CD8⁺CD25^high) function. …”

<b>Soil C mineralization and C-Fe coupling: a trade-off between Fenton reaction and </b><b>microbial activity</b><b> under straw mulching in banana orchards</b> by Lingbo Dong (19185916)

“…This mechanism, by which straw mulching promotes soil C mineralization through weakening the Fenton reaction, decreasing Fe-OC, and increasing microbial activity, contributes to a deeper understanding of C cycling in agricultural ecosystems under straw mulching.…”

Tracheostomy data. by Rajesh Kamath (17179960)

“…Patients with an ET had a significantly shorter ICU LOS median of 15 days (IQR 13,17) and a mechanical ventilation median of 13 days (IQR 11,14) than LT patients who had an ICU LOS median of 33 days (IQR 30,36) and a mechanical ventilation median of 31 days (IQR 27,33) respectively.…”

Flow diagram of patient selection. by Rajesh Kamath (17179960)

“…Patients with an ET had a significantly shorter ICU LOS median of 15 days (IQR 13,17) and a mechanical ventilation median of 13 days (IQR 11,14) than LT patients who had an ICU LOS median of 33 days (IQR 30,36) and a mechanical ventilation median of 31 days (IQR 27,33) respectively.…”