Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Methodology flow chart. by Sidra Aman Rana (14167473)

“…Moreover, the area of open land decreased significantly from 68.46% to 18.92%whereas the area under the built environment increased significantly from 7.77% to 36.51% from 1999—2019. …”

Image 1_Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage.jpeg by Peter Linde (22011383)

“…Introduction<p>Mesenchymal stromal cells (MSCs) have been evaluated as a local therapeutic option to treat osteoarthritis (OA) with conflicting clinical results. …”

CLIC1 upregulation accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells. by Jingtong Xiong (22272139)

“…<p>(a-c) The activities of SOD (a), CAT (b), and GSH-Px (c) were significantly reduced in OGD/R-treated HT22 cells compared to the control group, with the restoration of these antioxidant enzyme activities upon CLIC1 silencing. …”

Protocol for our RNA-seq. by Sabih Rashid (5618807)

“…GO enrichment was conducted using the Wormbase Gene Set Enrichment Analysis [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003144#pbio.3003144.ref046" target="_blank">46</a>,<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003144#pbio.3003144.ref047" target="_blank">47</a>]. …”

Data Sheet 1_Wilt disease reshapes rhizosphere microbiota in small yellow ginger soils.docx by Qing Sun (492552)

“…</p>Results<p>Ginger wilt disease significantly altered the rhizosphere soil bacterial community structure and composition: the relative abundance of Proteobacteria increased significantly, primarily due to the enrichment of the genus Ralstonia; conversely, the relative abundance of Acidobacteriota, Firmicutes, and Chloroflexi significantly decreased. …”

Data Sheet 1_Differential regulation of soil microecology in crop rotation systems of maize, seed pumpkin, and processing tomato.docx by Xingxing Liu (715957)

“…Notably, the SLa treatment significantly decreased soil total potassium content by 13.6%. …”

Analysis of connexin 43 expression in mice inoculated intravenously with EVs (green) or ICs (blue). by Alberto Cornet-Gomez (10676133)

“…<p>Confocal microscopy revealed decreased connexin 43 synthesis in mice injected with EVs and ICs <b>(A)</b>. …”

TNC promotes bone regeneration via inflammatory macrophage by Qian Ren (19955367)

“…The cell communication analysis identifies ITGA7 as a TNC receptor contributing to the recruitment of inflammatory macrophages. …”

DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx by Yuhan Zhang (2792089)

“…Retinal levels of inflammatory factors were significantly decreased in Ala-Gln-treated diabetic rats. …”

Supplementary file 1_Synergistic effects of potassium and gibberellin on the yield and quality of yellow pitahaya (Hylocereus megalanthus) fruits in the Peruvian Amazon.docx by Julio Cesar Santos-Pelaez (22674113)

“…The combination of 100 kg K₂O ha⁻¹ and 50 mg L⁻¹ GA₃ significantly improved fruit performance, with fruit weight (369.5 g), yield (12 t ha⁻¹), volume (322 cm³), and soluble solids (22.8°Brix), while acidity decreased (pH 4.87 vs. 4.55 in the control). …”

Analytic framework. by Muayad Albadrani (7495145)

“…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. …”

Descriptive statistics for the whole sample. by Muayad Albadrani (7495145)

“…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. …”

Data Sheet 1_Transformation of polyacrylamide during hydrothermal carbonization and pyrolysis.docx by Gaoxiang Qi (1626193)

“…However, as the temperature exceeded 180 °C, the deamination process was significantly enhanced. Concurrently, the pH of the liquid phase decreased, which could be attributed to the decomposition of high molecular polybasic acids into low-molecular weight organic acids. …”

Image 6_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”

Image 3_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”

Scorpion venom cytolytic peptide Smp43 induces caspase-dependent apoptosis in ovarian carcinoma cell line OVCAR-3 by Salwa I. Hussein (22234753)

“…Additionally, Smp43 significantly increased DNA fragmentation in OVCAR-3 cells and decreased antioxidant parameters. …”

Image 1_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”