Supplementary Material for: Glucosamine use reduces the risk of first-ever optic neuritis: A nationwide 16-year longitudinal analysis by Yang Y.-Y. (4130872)

“…Introduction: Evidence of neuroprotective effects of glucosamine on Asian optic neuritis (ON) patients remains sparse. We aimed to examine the longitudinal association between glucosamine use and the incidence of first-ever ON to identify the factors contributing to reducing ON risk in older Asian populations. …”

Image 1_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif by Viana Q. Pham (22081163)

“…Upon MSG exposure, fenestrated capillaries and vascular permeability were decreased in the ME but increased in the AP, and these changes were closely associated with the expression of angiogenic factors pleiotrophin (Ptn) and vascular endothelial growth factor A (Vegfa). …”

Image 3_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif by M. Elakkya (21760439)

“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”

Data_Sheet_1_Optimisation of Lactobacillus fermentation conditions and its application in the fermentation of salt-free sauerkraut.PDF by Wenlun Wang (18863641)

“…<p>To identify what are the dominant lactic acid bacteria (LAB) involved in the fermentation of salt-free sauerkraut, and optimize its industrial culture conditions, we isolated and identified a strain of LAB, which is referred to as Lactobacillus sp. …”

Data Sheet 1_Membrane filtration reduces nutrient availability and invasion potential in drinking water systems, without affecting mature biofilms.docx by Thomas Pluym (22046237)

“…NF achieved significantly higher TOC removal (75.4%) compared to UF (25.4%), with high performance size exclusion chromatography revealing almost complete removal of all molecular weight fractions in NF-treated water. …”

Image 4_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Table 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

“…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”

Table 1_Precipitation-driven restructuring of rhizosphere microbiota enhances alpine plant adaptation.xlsx by Chao Chen (195669)

“…Actinobacteria remained consistently dominant (31.56-34.62%), while Proteobacteria abundance decreased markedly in the rhizosphere post-rainfall. …”

Data Sheet 1_MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection.pdf by Arpa Aintablian (15648896)

“…Thus, we hypothesized that the defense against a subsequent BCG infection would be compromised in Mtb-immunized mice. …”

Table 1_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.xlsx by Shuwen Li (5058398)

“…The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”

Table 6_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx by M. Elakkya (21760439)

“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”

Glucose-6-phosphatase catalytic subunit 3 enhances host resistance to porcine epidemic diarrhea virus through regulating glycolysis/gluconeogenesis by Huihui Li (227521)

“…Notably, glucose-6-phosphatase catalytic subunit 3 (<i>G6PC3</i>) expression was significantly higher in Chinese Min piglets than in Yorkshire piglets. …”

Table_3_Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites.DOCX by Yexun Zhou (11711813)

“…The purpose of this study was to analyze the beneficial influences of adding feed additive TAX to boar semen in terms of its quality and potential mechanisms. We discovered that TAX increased sperm motility significantly in Duroc boars by the elevation of the protein levels such as ZAG, PKA, CatSper, and p-ERK for sperm quality. …”

Unpowered dust removal device stereogram. by Yuxuan Liu (349237)

“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”

Table 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx by M. Elakkya (21760439)

“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”

DataSheet1_Lats-IN-1 protects cardiac function and promotes regeneration after myocardial infarction by targeting the hippo pathway.PDF by Hua Shen (54290)

“…Additionally, Lats-IN-1 decreased infarct size and apoptosis rates while promoting cardiomyocyte proliferation. …”

Table 1_Immunoglobulin G N-Glycome as a biomarker of mortality risk in Escherichia coli induced sepsis.docx by Huachen Wang (11272203)

“…Immunoglobulin G N-glycome was compared with existing risk scores on predicting in-hospital death.</p>Results<p>We identified that the fucosylation level was significantly decreased in patients. …”

Image 3_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif by Tengfei Tian (1793545)

“…Objective<p>We investigated the effect of human beta defensin-2 (hBD-2) on nasal epithelial barrier function with methicillin-resistant Staphylococcus aureus (MRSA) infection in chronic rhinosinusitis with nasal polyps (CRSwNP).…”

<b>Collapsin response mediator protein 2 modulates synaptic function by stabilizing the surface expression of phosphorylated AMPA receptor GluA2 subunits</b> by ren (21408623)

“…Upon phorbol myristate acetate (TPA) induced activation of protein kinase C (PKC), the surface expression of GluA2 decreased significantly, as phosphorylation of GluA2 at the S880 site is known to promote its internalization. …”

Table 1_Case Report: Identification of a novel hemizygous CFAP47 variant in a primary ciliary dyskinesia patient with dual ciliary and flagellar defects.docx by Miao He (148269)

“…Experimental validation revealed significantly decreased CFAP47 mRNA levels in the patient’s sperm and the HEK293 cells transfected with mutant plasmid compared to controls, suggesting impaired transcript stability.…”