Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis by Shivam Kumar Pandey (22295532)

“…However, co<b>-</b>exposure with LPS and FeSO₄ resulted in a dose-dependent reduction in cell viability, which was significantly reversed by pretreatment with BA (0.3-30μM). …”

DataSheet1_UV-B induced flavonoid accumulation and related gene expression in blue- grained wheat at different periods of time.zip by Li Li (14993)

“…The genes for the enzymes FLS, ANR, HCT, CYP75A and CYP73A are more abundant, with F3H and FLS showing higher expression levels.…”

Table 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Table 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.tif by Haipeng Zhang (3413288)

“…Four hub genes—SRC, TLR8, FCAR, and HIF1A—were identified using LASSO and RF algorithms. …”

Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf by Igor Larrañaga (5434382)

“…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …”

Table 1_Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia.docx by Rongrong Zhou (3341903)

“…</p><p>Results: This study demonstrated that PCPs significantly mitigated body weight loss, restored muscle fiber atrophy and mitochondrial disorder, alleviated adipose tissue wasting, strengthened the intestinal barrier integrity, and decreased the intestinal inflammation in chemotherapy-induced cachexia. …”

Fig 3 - by Nehal Shawky Nagy (17721213)

“…<p>A) Pathologic assessment of H&E-stained sections of substantia nigra in different studied groups: control, DSMO, and gonadal extract groups show a compact cellular substania nigra in low power, high power shows viable neurons with large, rounded nuclei with open chromatin and a nucleolus (arrows). …”

Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip by Yupeng Li (507508)

“…Atorvastatin enhanced the antioxidant capacity of NPCs and decreased intracellular ROS accumulation. It promoted Nrf2 activation and upregulated the expression of downstream antioxidant factors, thereby exerting a protective effect against oxidative stress–induced injury. …”

Table 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.docx by Haipeng Zhang (3413288)

“…Four hub genes—SRC, TLR8, FCAR, and HIF1A—were identified using LASSO and RF algorithms. …”

Hypoxia response and tracheogenesis in <i>PGR</i> mutants. by Daiki Fujinaga (21301129)

“…<p>(A) Relative expression levels of <i>branchless</i> (<i>bnl</i>) in <i>PGR</i> mutants from 0 to 96 hours after puparium formation (APF). …”

Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z... by Peng Ren (337555)

“…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…”

Ictogenic changes in input correlation and adaptation gains are associated with increased dynamical variability during baseline activity. by Scott Rich (9873638)

“…<p><b>A</b>: SLE rate (SLEs/s) as a function of input correlation <i>c</i>. …”

Table 2_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Introduction<p>High consumption of dietary carbohydrates (nitrogen-free extract, NFE) in extruded dry foods is postulated as a risk factor for feline obesity, though evidence is limited. …”

Table 1_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Introduction<p>High consumption of dietary carbohydrates (nitrogen-free extract, NFE) in extruded dry foods is postulated as a risk factor for feline obesity, though evidence is limited. …”

Optimisation of read depth, DNA quantity, and unique alternate observation threshold. by Melinda L. Tursky (20790436)

“…Lower read depth may contribute to an overestimated VAF of very small variants, although differences did not reach significance. D-F: Blood samples from 383 community-dwelling subjects were sequenced at a target depth of 3,000-4,000 × . …”

TraN directs surface exclusion specificity. by Nicolas Rivard (3875746)

“…<p>(A) The absence of <i>eexC</i> and <i>sfx</i> in the donor decreases the frequency of transconjugant formation. pClo (Ap^r) was mobilized from <i>E</i>. …”

Data Sheet 1_Inflammation-related biomarkers and berberine therapy in post-stroke depression: evidence from bioinformatics, machine learning, and experimental validation.docx by Wei Liu (20030)

“…Objective<p>Post-stroke depression (PSD), a common neuropsychiatric complication, significantly hinders stroke recovery and quality of life. …”

Integrated bioinformatic and experimental study links cyclin B1/B2 to poor prognosis and immune infiltration in endometrial cancer by Haikun Yang (14815742)

“…</p> <p>Endometrial cancer is a common cancer originating in the uterus lining. …”

Table 1_The temporal change of heat exposure and adaptation capacity in Chinese adults from 1994 to 2023.doc by Xiaohui Ji (711427)

“…Long duration outdoors work (≥4 h) decreased from 36.01, 30.93 to 24.53% (Z = −9.80, p < 0.01) and bicycling/walking decreased from 62.3, 27.9, to 9.7% (CMH value = 156.40, p < 0.01) significantly during the last three decades. …”