Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

“…While some previous studies reported that CYP3A5 variants were associated with decreased blood pressure and risk of HTN, others reported no associations. …”

Raw data for hand and arm dysfunction following hemodialysis access placement by Kyoungrae Kim (10312460)

“…RESULTS: Six weeks post-surgery, patients exhibited significant functional decline in the access limb. Postoperative grip strength declined by approximately 15% (P=0.0015), finger pressure decreased by ~30 mmHg (P<0.0001), and the perceived HAD score increased significantly (P=0.0450) compared to the preoperative values. …”

DtpT transports structurally diverse di-/tripeptides. by Imran Khan (109715)

“…(<b>C</b>) Transport of 20 peptides was compared by quantifying the change in pyranine fluorescence over the first 30 seconds of the assay. Bars indicate the mean of three replicates ± standard deviation. Coloured bars indicate a change in fluorescence which differs significantly from the no peptide (“Water”) control. …”

Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study by Kazuaki Oyake (7481357)

“…These individuals demonstrated significantly greater orthostatic cardiac index increases (F_(5,105) = 2.75, <i>p</i> = 0.023, partial η² = 0.126) and more pronounced orthostatic total peripheral resistance index decreases (F_(5,105) = 4.19, <i>p</i> = 0.002, partial η² = 0.166) than those without orthostatic hypotension.…”

<b>Climate warming, rather than nitrogen deposition, reduces plant diversity and increases community homogenization in a desert steppe</b> by Yi Zhu (22625741)

“…Over this period (2006–2022), warming (mean annual temperature + 1.4°C) significantly decreased species richness and functional α-diversity throughout the experiment, whereas its effects on phylogenetic α-diversity and community phylogenetic structure were significant only before 2015 and disappeared thereafter, likely due to an extreme drought that reset the community composition. …”

Table 2_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 1_Affective bias predicts changes in depression during deep brain stimulation therapy.docx by Brian Cui (20932658)

“…Linear mixed-effects modeling was used to assess changes in bias scores over time and their relationship with depression severity measured by the Hamilton Depression Rating Scale (HDRS-17).</p>Results<p>We observed significant improvements in total affective bias scores over the course of DBS treatment in both cohorts. …”

Table 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 3_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Image 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.jpg by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Propofol wash-in. by Anne S. Fleiner (20496284)

“…The decrease in spiking after wash-in of 3 μM and 10 μM was not significantly different (MWU test; 0 μM: n = 10; 3 μM: n = 8; 10 μM: n = 10). …”

Data Sheet 1_Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients with irritable bowel syndrome—A rand... by Adrianna Wierzbicka (14130159)

“…A significantly higher concentration of all SCFAs was seen after intervention in Group III compared to control Group I.…”

Continuing evolution of H5N1 highly pathogenic avian influenza viruses of clade 2.3.2.1a G2 genotype in domestic poultry of Bangladesh during 2018–2021 by Mohammed Nooruzzaman (3175290)

“…<p>We characterized 15 H5N1 HPAI viruses from different small- and medium-scale poultry flocks across Bangladesh during 2018–2021 based on their complete genome sequences. …”

Table 1_Study on the invitro synergistic susceptibility and biofilm inhibition mechanism of ceftazidime-avibactam combined with aztreonam against carbapenem-resistant Klebsiella pn... by Guangfen Wang (20906201)

“…</p>Results<p>The comparison of synergistic indices for different enzyme-type CRKP strains with CZA and ATM combination therapy showed a statistically significant difference (p < 0.01). The time-kill assay indicated that the time-kill curves for strains carrying blaKPC-2 and blaNDM-1 resistance genes were similar between the monotherapy and combination therapy groups, while the CZA + ATM combination therapy group showed a significant decrease in bacterial concentration after 4–8 h of cultivation compared to the CZA and ATM monotherapy groups. …”

Data_Sheet_1_Supplementation with inulin reverses cognitive flexibility alterations and modulates the gut microbiota in high-fat-fed mice.docx by Gabriela González-Velázquez (20131497)

“…The I group showed a decrease in bacterial diversity compared to the HF group. …”

Table 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.xlsx by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”

Data Sheet 2_Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990–2021 analysis and future projections.docx by Ming Liu (105953)

“…</p>Results<p>From 1990 to 2021, the global burden of AGN among children and adolescents remained significantly high. In 2021, there were approximately 170,584 new cases, representing a decrease compared to earlier years, with an age-standardized incidence rate (ASIR) of 6.47 per 100,000 (95% UI: 4.79–8.45). …”

Image 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.pdf by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”