Showing 6,141 - 6,160 results of 6,756 for search 'significant ((changes decrease) OR (largest decrease))', query time: 0.32s Refine Results
  1. 6141

    Table 1_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx by Qi Zhang (28502)

    Published 2025
    “…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
  2. 6142

    Effect of session on winning model parameters for set size = 2 and set size = 4 for both male and females. by Juliana Chase (20469427)

    Published 2024
    “…Use of one-back strategy parameters changed significantly across sessions for male mice with (C) S1 “Inappropriate Lose Shift” decreasing across sessions, <i>p</i> = 0.01 (D) S2 = S4 “Stimulus Insensitive Win Stay” increasing, <i>p</i> = 0.009 and (E) S3 “Inappropriate Lose Stay” decreasing, <i>p</i> < 0.0001. …”
  3. 6143

    DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

    Published 2024
    “…It effectively alleviates oxidative stress and inflammatory responses, reduces cell apoptosis, and improves the pathological changes in the retina of rat models of RGCs damage, thereby decreasing RGCs death. …”
  4. 6144

    Table 2_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx by Qi Zhang (28502)

    Published 2025
    “…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
  5. 6145

    Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg by Mouying Du (21398510)

    Published 2025
    “…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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  18. 6158

    The impact of anesthesia and positioning on cerebral blood flow and pressure in patients undergoing laparoscopic surgery: an randomised observational study by alon lord (20342469)

    Published 2024
    “…In the REV group, CCA flow decreased after the Reverse Trendelenburg position (P=0.0213). …”
  19. 6159

    Table 1_Inflammatory markers CRP and WBC as predictors of liver function impairment in multiple injury trauma patients: a repeated measures analysis.docx by Gang Wang (36685)

    Published 2025
    “…</p>Conclusion<p>CRP and white blood cell count significantly correlate with liver function changes in multiple injury patients, with marked gender-specific differences in these associations. …”
  20. 6160

    Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx by Jikai He (11888466)

    Published 2025
    “…</p>Methods<p>(1) Fecal samples from CRC patients (n=26) and healthy controls (n=20) were collected for metagenomic sequencing and untargeted metabolomics analysis; (2) The ability of B.o to produce NMS from orange fiber was validated in vitro; (3) A CRC mouse model was established using azoxymethane (AOM)/dextran sulfate sodium (DSS) induction, followed by evaluation of body weight, rectal bleeding, colorectal length, tumor number, and intestinal barrier function; (4) Network pharmacology, molecular docking, and western blot analysis were combined to verify the mechanism of action; (5) 16S rRNA sequencing was performed to analyze gut microbiota changes.</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”