Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…PTA decreased as CrCL increased, with slight variations observed across different PLT levels. …”

Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... by Yuhua Jiang (10300159)

“…PSCK9 inhibitors and potent statins significantly reduced LDL-C levels from baseline vs. placebo regardless of background therapy. …”

Image 1_Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers.tiff by Gaetano Zizzo (15853004)

“…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”

Image 2_Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers.tiff by Gaetano Zizzo (15853004)

“…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”

Supplementary Material for: Off-label Use of Mycophenolate Mofetil in Immunoglobulin A Nephropathy: A Systematic Review and Meta-analysis by Feng L. (5056958)

“…Conclusion: MMF administration in IgAN indicates promising in decreasing the occurrence of MAKDE, reducing proteinuria level, and lessening the probability of doubling blood creatinine, but also comes with the risk of infection. …”

The global disability-adjusted life years (DALYs) for asthma attributable to nitrogen dioxide pollution from 1990 to 2021 and predicted the trends from 2022 to 2050 by Yaping Feng (427666)

“…Additionally, it is still quite significant for children under the age of 15 and in some underdeveloped regions.…”

Table_1_Olfactory dysfunction as an early pathogenic indicator in C. elegans models of Alzheimer's and polyglutamine diseases.xlsx by Weikang Xue (19768329)

“…At the molecular level, Aβ1-42 or Q40 expression caused age-dependent protein aggregation and morphological changes in neurons. …”

Table 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.xlsx by Yu Xia (8822)

“…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …”

Data Sheet 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.pdf by Yu Xia (8822)

“…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …”

Table 1_The global burden of childhood diarrhea and its epidemiological characteristics from 1990 to 2021.doc by Hai-Yan Zhu (17595684)

“…The ASPR is mostly concentrated in children aged 10–14 years old, among which the ASPR of children under 5 years old has the most significant decline, from 3,138.81 per 100,000 people (95% UI: 2,749.19–3,557.51) in 1,990–885.07 per 100,000 people (95% UI: 755.93–1,029.39), a decrease of 71%. …”

eIF3d1 phosphorylation but not cap-binding is required for CySC self-renewal. by Ruoxu Wang (9312306)

“…Phospho-dead eIF3d1 expression results in a significant decrease in CySC numbers (<i>N</i> ≥ 18 testes, * <i>P</i> < 0.05, ns <i>P</i> = 0.1150 (eIF3d1^WT) or <i>P</i> > 0.9999 (eIF3d1^DD), Kruskal-Wallis test). …”

Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b> by Lucy Aliette Janet Mirabib Ame De Guilhem De Lataillade (11192853)

“…</p><p dir="ltr">These larger phenomena were analysed in greater detail through an examination of the Hong Kong mosquito microbiome. …”

Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…Subgroup analysis revealed that FFYH improved the recovery time of clinical symptoms, improved hematological parameters, and controlled excessive cytokine storms to a greater extent in the mild COVID-19 male subgroup, abnormal hematology subgroup, and 32–42-year-old subgroup than in the corresponding LHQW subgroup (P < 0.05). …”

Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…Subgroup analysis revealed that FFYH improved the recovery time of clinical symptoms, improved hematological parameters, and controlled excessive cytokine storms to a greater extent in the mild COVID-19 male subgroup, abnormal hematology subgroup, and 32–42-year-old subgroup than in the corresponding LHQW subgroup (P < 0.05). …”

Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx by Makoto Takahashi (386772)

“…FW-D-fed fish also exhibited significantly increased muscle levels of unsaturated fatty acids, particularly docosahexaenoic acid (DHA), a nutrient beneficial for human health. …”

PbCBP-O is required for efficient midgut traversal. by Dominika Kwecka (22170493)

“…Western blot of culture supernatants from wild type and PbΔCBP-O ookinetes show similar levels of chitinase secretion (right panel), representative data from 2 independent experiments, <b>(D)</b> Immunofluorescence showing decreased ookinete presence in the basal side of mosquito midguts. …”

Dynamic changes in mRNA stability. by Shiqi Luo (3829597)

“…As a result, each rows have the same mean value of 0 and standard deviation of 1. BMDM: mouse bone marrow-derived macrophage. …”

Data Sheet 1_Effect of environmentally relevant concentrations of estrogens on the aggressive response of male zebrafish.docx by Ying–Ying Zhang (21776942)

“…Post-exposure assays (mirror test and dyadic interaction) revealed that Mix significantly reduced the frequency of approaching mirror, the attack mirror duration, and the frequency of chasing un-exposed fish, indicating a decrease in aggressive behaviour in Mix-fish. …”

Supplementary Material for: Assessment of the Factors Influencing Early Detection Practices of Oral Carcinomas by Dentists: A Cross-Sectional Study by figshare admin karger (2628495)

“…With increasing duration, the early detection practice scores decreased. Moreover, “guidelines about OC examinations” significantly predicted practice scores (higher scores where written guidelines were present) (P<0.001). …”

Data Sheet 1_Valve-in-valve transcatheter aortic valve replacement (TAVR) leads to lower device success compared to TAVR in native stenosis.pdf by Michael Paukovitsch (16428786)

“…The overall rate of device success amounted to 66% in ViV-TAVR, compared to 96.1% in TAVR (p < 0.01) and ViV-TAVR was independently associated with reduced device success (OR: 0.07, 95%CI: 0.045–0.12, p < 0.01) in multivariate regression. While ViV-TAVR decreased peak and mean gradients significantly, in 31% of patients elevated mean gradients (≥20 mmHg) were observed at discharge. …”