Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx by Reema Priyanka Suram (22399759)

“…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …”

Data Sheet 1_Dangua Fang induces anti-glucolipid metabolism disorder effects similar to those of direct NFIL3 inhibition.zip by Zhuang Han (471130)

“…The NFIL3 mRNA and protein expression levels in the serum, liver, and small intestine were significantly decreased. …”

Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…Decreased CYP2J3 expression along with reduced PPAR-α levels, likely contributed to reduced anti-inflammatory EET levels, while elevated soluble epoxide hydrolase increased pro-inflammatory dihydroxyeicosatrienoic acids. …”

Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…Decreased CYP2J3 expression along with reduced PPAR-α levels, likely contributed to reduced anti-inflammatory EET levels, while elevated soluble epoxide hydrolase increased pro-inflammatory dihydroxyeicosatrienoic acids. …”

Data Sheet 1_Disease burden of tuberculosis in China from 1990 to 2021 and its prediction to 2036.docx by Rong Sun (532754)

“…</p>Conclusion<p>TB burden in China has decreased significantly overall in the past years. …”

Zika virus replicates efficiently in the zebrafish model and induces morphological defects. by Aïssatou Aïcha Sow (20371233)

“…<i>N</i> = 3). Data are shown as means ± SEM. **** P ≤ 0.0001; ns = not significant; one-way ANOVA. …”

Supplementary Material for: Exosomal TIMP4 from myocardial cell relieves heart failure by influencing Th17/Treg Balance by figshare admin karger (2628495)

“…Furthermore, TIMP4 overexpression decreased IL-17 levels and the Th17 cell proportion while promoting Treg cell differentiation and increasing IL-10 levels. …”

DataSheet2_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Image 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.tif by Peng Zhang (2071)

“…Additionally, in vivo experiments indicated that BBR reduced aortic lipid deposition and reduced the atherosclerotic plaque area. BBR decreased the expression levels of RAGE, p-NF-κB, TNF-α, and P62 in the aorta, and upregulated the expression levels of IL-10, CD31, VEGF, LC3B, and Beclin1. …”

Table 2_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.docx by Yue Song (162328)

“…</p>Results<p>Both the low-frequency electroacupuncture group and the high-frequency electroacupuncture group significantly reduced writhing scores, increased spleen index, decreased prostaglandin PGF2α and COX-2 levels, and increased prostaglandin PGE2 and β-EP levels to varying degrees.…”

DataSheet3_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Table 1_Serum neurotransmitter analysis of motor and non-motor symptoms in Parkinson’s patients.docx by Yichun Fan (14295492)

“…Specifically, levels of Trp, kynurenine (KYN), kynurenic acid (KA), nicotinamide (NAM), and 5-methoxyltryptamine (MeOTA) were substantially decreased. …”

Data Sheet 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.pdf by Ye Li (290115)

“…Knocking down ATF4 decreased ARL5B protein levels. ChIP experiments and dual-luciferase assays confirmed ATF4 positively regulates ARL5B. …”

Table 4_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.docx by Yue Song (162328)

“…</p>Results<p>Both the low-frequency electroacupuncture group and the high-frequency electroacupuncture group significantly reduced writhing scores, increased spleen index, decreased prostaglandin PGF2α and COX-2 levels, and increased prostaglandin PGE2 and β-EP levels to varying degrees.…”