Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx by Juan Liu (6492)

“…</p>Methods<p>In this study, we evaluated the synergism of tigecycline combining with other antibiotics as a means of overcoming the tet(X)-mediated resistance in Acinetobacter spp. …”

Prolonged sitting time and all-cause mortality: the mediating and predictive role of kidney function markers by Li Wang (15202)

“…</p> <p>A total of 9,707 adults were included in the analysis. There was a significant increase in the levels of blood urea nitrogen (BUN), creatinine, uric acid, osmolality, and UACR with extended daily sitting time, while eGFR significantly decreased. …”

Data Sheet 1_The association between lipid accumulation product and osteoporosis in American adults: analysis from NHANES dataset.docx by Huawen Pan (20899496)

“…</p>Results<p>LAP and osteoporosis were shown to be significantly inversely correlated in the study. In the unadjusted model, the prevalence of osteoporosis and Log LAP showed a significant negative connection (OR = 0.62, 95% CI = 0.52–0.74). …”

Table 1_Association between composite dietary antioxidant index and increased urinary albumin excretion: a population-based study.docx by Shaopeng Li (820947)

“…The prevalence of increased ACR decreased across the CDAI quartiles from 13.89% in Q1 to 10.11% in Q4. …”

Innovation in a Post-Oil City: Moving Design Away from Carbon Dependency by Idrees Rasouli (22174948)

“…We also need to understand the more significant stories that have led to oil-dependent ways of innovation being seen as a colonial and universal model and oil’s essence and essential role in shaping modernity and our everyday lives. …”

Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx by Reema Priyanka Suram (22399759)

“…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …”

Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf by Xiaohua He (361530)

“…The smoothed curve revealed a linear relationship between BRI and CVD, but a U-shaped association between the BRI and CHF. For CVD, stratified analyses did not show significant difference between strata. …”

Data Sheet 4_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Table 3_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Data Sheet 3_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Data Sheet 10_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Table 7_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Data Sheet 6_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Table 4_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Table 6_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Table 10_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Data Sheet 9_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Data Sheet 7_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”

Table 9_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls by Meizhi Liu (21898892)

“…A U-shaped relationship between SDI and MSDs burdens was observed, with middle-SDI regions generally performing better.…”