UHPLC-MS CKO vs K5Cre results. by Kevin J. Mills (9270966)

“…Lipidomic analysis of epidermis using advanced chemical separations and tandem mass spectrometry identified 470 individual lipids in epidermis with 165 significantly decreased and 82 significantly increased in CKO epidermis. …”

Uncropped raw western blot images. by Kevin J. Mills (9270966)

“…Lipidomic analysis of epidermis using advanced chemical separations and tandem mass spectrometry identified 470 individual lipids in epidermis with 165 significantly decreased and 82 significantly increased in CKO epidermis. …”

LC-IMS-CID-MS CKO vs K5Cre results. by Kevin J. Mills (9270966)

“…Lipidomic analysis of epidermis using advanced chemical separations and tandem mass spectrometry identified 470 individual lipids in epidermis with 165 significantly decreased and 82 significantly increased in CKO epidermis. …”

Phospholipid metabolism CKO vs K5Cre Reactome. by Kevin J. Mills (9270966)

“…Lipidomic analysis of epidermis using advanced chemical separations and tandem mass spectrometry identified 470 individual lipids in epidermis with 165 significantly decreased and 82 significantly increased in CKO epidermis. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Additionally, we found that a large concentration of negative charge at the surface of the POPA-based membrane greatly increased the number of contacts with lipid molecules and significantly decreased the exposure of intracellular NKG2A ITIM regions to water molecules, thus likely halting the signal transduction process. …”

Join-point regression analysis of the statistically significant linear increase in use of anxiolytics, psychostimulants and noot ropic drugs, sedatives and hypnotics, gabapentinoid... by Jelena Filimonovic (22305307)

Infection of humanized mice resulted in decrease in pathogenicity in HTLV-1-CTCF infected mice. by Ancy Joseph (5634794)

Juvenile demyelination impairs the maturation of PV interneurons in the PFC. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …”

All data points from Fig 2. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 5. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 8. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 3. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 1. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 4. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 9. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 7. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 6. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …”

Adult demyelination has no effect on PV interneuron’s firing rate or failures in autaptic responses. by Sara Hijazi (21656615)

Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …”