Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 2_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx by Jae-Chang Sim (22335904)

“…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…”

Table 1_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx by Jae-Chang Sim (22335904)

“…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…”

Behavior is best fit by models with independent attributes. by Aster Q. Perkins (22008260)

“…Positive/negative coefficients on option A/B indicate that the probability of choosing option A increases/decreases with the magnitude of that attribute. …”

Data Sheet 1_Active layer and permafrost microbial community coalescence increases soil activity and diversity in mixed communities compared to permafrost alone.docx by Stacey J. Doherty (6629561)

“…Respiration rates were highest in the 100% active layer soils, averaging 19.8 μg C-CO₂ g^–1 dry soil d^–1 across both sites, and decreased linearly as the ratio of permafrost increased. …”

Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”

SEAwise report on the impact of socioeconomic effects of fisheries management adapted according to input from review workshops by Isabella Bitetto (20145735)

“…Lusitanian fish species and cephalopods are already contributing significantly to North Sea fisheries revenues, although boreal species remain dominant, particularly in ICES areas 27.4 and 27.3.A. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”

Broader frequency tuning in auditory cortex of <i>Fmr1</i> KO rats despite unaltered subcortical tuning properties. by D. Walker Gauthier (21637726)

“…Boxplots dots represent individual multiunit clusters. All other values are means ± SEM. **<i>p</i> < 0.01, ***<i>p</i> < 0.0001, ns = not significant. …”

Sound evoked cortical activity across vigilance states before and after NOE. by Linus Milinski (10532121)

“…Data are averages across response components, sound level and stimulus type based on bootstrap means ± standard errors (See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0304306#sec002" target="_blank">methods</a>). …”

<i>mig-21</i> sensitizes adult DTCs to polarizing signals. by Xin Li (51274)

“…An “extra turn” to “overmigration” defect shift was observed. A robust “extra turn” defect rate of control on <i>vab-3</i> RNAi (n=38/57) decreases with <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=24/65), p < 0.01. …”

Table 1_The effect of self-compassion versus mindfulness interventions on autonomic responses to stress in generalized anxiety disorders.docx by Xuejun Qi (3842173)

“…We also demonstrated a significant correlation between decreased heart rate response and less negative emotions.…”

Table 1_Case Report: Application of accelerated continuous theta burst stimulation in treatment-resistant depression.docx by Guilan Sun (10587560)

“…<p>Treatment-resistant depression (TRD) poses a significant challenge in psychiatric practice. …”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…<p>(A) OVD injections led to IOP increase, with values presented as means ± SD. …”

Data Sheet 1_Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors.docx by Monika Marko (7926311)

“…Objective<p>The study is based on a respiratory educational program aimed at training medical personnel to use inhalers correctly and educating patients on improving their inhalation skills.…”

Table_1_Toward workforce integration: enhancements in adaptive behaviors and social communication skills among autistic young adults following vocational training course.DOCX by Yael Lousky (20414456)

“…No significant Time x Group interaction was found for any of the examined measures, meaning similar trends were observed in all three vocational groups.…”

CARE-checklist JOSPT[1].docx by Sanjivani Bangde (19749151)

“…The patient’s pain levels decreased, and functional status improved as indicated by a reduction in score.…”

Table 1_Organic and inorganic fertilizers modulate the response of the soil microbiome to salinity stress.docx by Halima Malal (21570602)

“…Over the long-term, the microbial community evolved into a new pattern under salt stress, favoring the presence of Bacteriodota, a salt-tolerant phylum, while decreasing the relative abundance of Acidobacteriota and Planctomycetota, which are more salt-sensitive. …”

Photomicrograph of the gastric mucosa colored with an anti-caspase-3 antibody. by Rehab F. Taher (20478600)

“…<p>The percentage of caspase-3 positive cells having strong brown coloring is reduced in the omeprazole group (c), while the control ethanol group (d) exhibited increased expression of caspase-3 and a higher percentage of positive cells with powerful brown cytoplasmic and/or nuclear coloring, (d) PM-EtOH (25 mg/kg) group showing decreased expression of caspase-3, along with the presence of moderately stained cells, (e) PM-EtOH (50 mg/kg) group showing decreased percentage of caspase-3 positive cells, (f) PM-EtOH (100 mg/kg) group showing weak caspase-3 expression, via a significant lowering in caspase-3-positively colored cells. …”