Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

The global changes of AS prevalence, DALYs, and mortality rates of IBD among women from 1990 to 2021. by Jiefeng Zhao (9090305)

Frontier analysis for the potential for improvement in reducing the burden of IBD among WCBA across 204 countries and regions. by Jiefeng Zhao (9090305)

Colocalization results. by Marie C. Sadler (9649799)

“…Mice experiments showed that dietary zinc deficiency decreased urinary but not plasma zinc levels, and upregulated kidney <i>Slc30a2</i> expression. …”

Finemapping results. by Marie C. Sadler (9649799)

“…Mice experiments showed that dietary zinc deficiency decreased urinary but not plasma zinc levels, and upregulated kidney <i>Slc30a2</i> expression. …”

List of RT-qPCR primers. by Marie C. Sadler (9649799)

“…Mice experiments showed that dietary zinc deficiency decreased urinary but not plasma zinc levels, and upregulated kidney <i>Slc30a2</i> expression. …”

Image2_Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.TIF by Tetyana P. Buzhdygan (19822401)

“…We found that ADMA disrupted physical barrier function as evident by significant decrease in electrical resistance and increase in paracellular permeability of hBMVEC monolayers. …”

Image1_Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.TIF by Tetyana P. Buzhdygan (19822401)

“…We found that ADMA disrupted physical barrier function as evident by significant decrease in electrical resistance and increase in paracellular permeability of hBMVEC monolayers. …”

A cycle of lung ultrasound (Video). by An-Xia Deng (22386214)

“…<div><p>This study evaluated the effectiveness of non-invasive ultrasound technology in monitoring pulmonary edema in a mouse model of acute lung injury (ALI). Male C57BL/6J mice were instilled through the trachea with lipopolysaccharide (LPS, 5 mg/kg, single dose) to induce ALI. …”

DataSheet1_RETRACTED: Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn.DOCX by Kislay Roy (3466256)

“…The blood analysis revealed a substantial decrease in the RBC, WBC, platelets, or the hemoglobin content post alkali burn. …”

Channel pruning process. by Zhongjian Xie (4633099)

“…<p>After channel pruning, the algorithm model experiences a significant reduction in parameters and computational load, yet it may incur a decrease in accuracy. …”

Genes with highest fold change in exponential compared to stationary phase. Genes with >10 fold enrichment are shown, ribosomal genes are highlighted with bolded text. <i>rpsJ</i>/... by Justin Greene (306625)

Microbial differential abundance at 24 hours post-treatment was assessed using ANCOM (<i>P</i> <  0.05). by Elena G. Olson (10649705)

“…</i> Typhimurium DT104, and <i>S.</i> Reading. (a) The abundance of amplicon sequencing variants (ASVs) within <i>Enterobacterales</i> significantly decreased in the 1.25% SCFP treatment compared to the control at 24h, particularly in samples where <i>Salmonella</i> reduction was significant. …”

The statistical data of the partial graph. by Si Yu Zhao (19544793)

“…Behavioral tests of both mutant and control strains revealed that the <i>rho-l</i>^{<i>△807</i>} mutant mosquitoes had a significant decrease in their ability to search for preferred oviposition sites that correlated with a reduced ability to recognize long-wavelength red light. …”

Experimental Design Flowchart. by Si Yu Zhao (19544793)

“…Behavioral tests of both mutant and control strains revealed that the <i>rho-l</i>^{<i>△807</i>} mutant mosquitoes had a significant decrease in their ability to search for preferred oviposition sites that correlated with a reduced ability to recognize long-wavelength red light. …”

Raw data underlying figures 1–7. by Alejandra Barrera-Rosales (21656278)

“…In M0 and M2 macrophages, the SMPs induced a mixed secretion of cytokines such as TNF-α, IL-10, and IL-12p40, and a significant decrease of TGF-β1. …”

The percentage change in DALYs for head and neck cancers in the Asia between 1990 and 2021. by Mengjuan Ding (21560393)