Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur... by Yangtian Jiao (21725018)

“…</p>Methods<p>Using the GBD 2021 dataset, we evaluated the burden of AGN in terms of incidence, mortality, and disability-adjusted life years (DALYs). …”

Table 1_High humidity environment increases FBG by impairing the intestinal barrier.xlsx by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Table 1_Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission.xlsx by Michele Francesco Di Tolla (12503167)

“…After dietary intervention, a significant reduction in specific inflammatory and metabolic biomarkers was observed, with distinct effects depending on tumor type. …”

Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Table 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx by Yali Han (4676677)

“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”

<b>Differential Effects of Retinol-Binding Protein 3 and Anti-VEGF Antibodies on Retinal Dysfunctions in Diabetic Retinopathy</b> by Qin Li (36669)

“…Since elevation or overexpressing retinol binding protein 3 (RBP3) decreased risks for retinal pathologies and progression to severe DR, we compared the therapeutic profile of RBP3 and anti-VEGF to normalize retinal dysfunctions induced by diabetes. …”

Table 2_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx by Giacomo Brisca (10963929)

“…The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …”

<b>Social conditions alter the growth, metabolic rate, behavioral traits, and food-shelter preferences in the qingbo </b><b><i>Spinibarbus sinensis</i></b> by Yu-Lin Zhang (9129227)

“…These findings suggest that visual social isolation may not be a significant stressor for qingbo, as the isolation-reared qingbo exhibited improved growth. …”

Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx by Hongliang Gu (21671054)

“…Introduction<p>The Guangxi Zhuang Autonomous Region of China is home to numerous Ficus altissima Blume (F. altissima) ancient trees over 300 years old, which hold significant cultural, ecological, and scientific research value. …”

DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”

Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx by Yuwei Mi (18003969)

“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”

DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”

Image 1_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff by Songtao Li (186776)

“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”

Image2_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”

Alterations in gut microbiota and plasma metabolites in patients with generalized anxiety disorder: a multi-omics study by Yi Li (1144)

“…</p> <p>Ninety subjects (60 patients with GAD and 30 healthy volunteers) were included. We employed 16S rRNA gene sequencing to characterize the gut microbiota and targeted liquid chromatography–mass spectrometry to analyze plasma metabolomic profiles.…”

Table 2_High humidity environment increases FBG by impairing the intestinal barrier.docx by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Image 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff by Songtao Li (186776)

“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”

Data Sheet 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.pdf by Yali Han (4676677)

“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”

Supplementary Material for: Comprehensive Genetic Analysis Exploring Sedentary Lifestyle, Physical Activity, and Respiratory Diseases: A Bidirectional Mendelian Randomization with... by Wan W. (4013744)

“…Despite numerous studies, uncertainties and controversies regarding causal relationships persist. We utilized Mendelian randomization (MR) analysis, an advanced statistical tool, to further investigate causal links. …”