Supplementary file 2_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx حسب Jinghuai Ni (21023477)

"…Objectives<p>Scorpion and Centipede (SC) is an ancient formula of traditional Chinese medicine that is commonly utilized in a range of disorders, and it has been shown to have pharmacological effects on postmenopausal osteoporosis (PMOP). …"

Table 1_Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars.doc حسب Xiaohui Sun (520181)

"…<p>Salinity is a major abiotic stress that threatens crop yield and food supply in saline soil areas. …"

Table2_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.docx حسب Chunjie Liu (3437477)

"…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …"

Supplementary file 1_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx حسب Jinghuai Ni (21023477)

"…Objectives<p>Scorpion and Centipede (SC) is an ancient formula of traditional Chinese medicine that is commonly utilized in a range of disorders, and it has been shown to have pharmacological effects on postmenopausal osteoporosis (PMOP). …"

Data Sheet 5_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf حسب Qi Dong (119569)

"…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"

Global maximum GPP from 2001-2018 حسب Xu (7493744)

"…The GPPmax estimates from this study and the changes in their trends were highly correlated with GPPmax estimates from the vegetation photosynthesis model, with R2 > 0.70 for most vegetation types. The GPPmax significantly increased in western North America, northern Europe, and eastern China, but decreased in tropical regions. …"

Image1_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.tif حسب Chunjie Liu (3437477)

"…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …"

Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx حسب Yihan Liu (2258221)

"…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …"

Data Sheet 2_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.docx حسب Qi Dong (119569)

"…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"

Data Sheet 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx حسب Yihan Liu (2258221)

"…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …"

Table1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.xlsx حسب Hongling Qin (5557505)

"…To further improve the performance of COSMO-RS, two options were used, i.e., the polynomial expression to correct the COSMO-RS results and the combination of COSMO-RS and machine learning algorithms (eXtreme Gradient Boosting, XGBoost) to develop a hybrid model. The results show that the COSMO-RS with correction can significantly improve the prediction of CO₂ solubility, and the corresponding average absolute relative deviation (AARD) is decreased from 43.4% to 11.9%. …"

Data Sheet 1_Flaxseed intervention and reproductive endocrine profiles in patients with polycystic ovary syndrome: an open-labeled randomized controlled clinical trial.pdf حسب Zahra Najdgholami (21009269)

"…</p>Results<p>After 12 weeks, the flaxseed group showed a significant increase in FSH levels compared to the control group. …"

Table 1_Association between higher estimated glucose disposal rate and reduced prevalence of hyperuricemia and gout.docx حسب Pengfei Liu (136115)

"…</p>Conclusion<p>A significant inverse association was observed between eGDR and the prevalence of HUA and gout. …"

Figure 5 from Multiplexed Imaging Mass Cytometry Reveals Tumor-immune Microenvironment–dependent Hormone Receptor Expression in Adult-Type Ovarian Granulosa Cell Tumors حسب Eleonora Y. Khlebus (20814571)

"…Colors of heatmap display gene expression <i>Z</i>-scores that are computed on a gene-by-gene basis: Increased expression (red) and decreased expression (blue). …"

The components of Qili Qiangxin capsule. حسب Minyan Sun (19751378)

"…Hematoxylin and eosin, Masson, and Picrosirius red staining under a light microscope indicated that QLQX treatment suppressed fibrosis and promoted angiogenesis by decreasing the protein expression levels of proteins related to cardiac remodeling including transforming growth factor-β1, metalloproteinase-9 and α-smooth muscle actin and increasing the expression of tissue inhibitor of matrix metalloproteinase-1 concentration. …"

FLEXI interactions with RNA-binding proteins. حسب Jun Yao (9646)

"…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …"

Data Sheet 1_Machine learning assisted breathomic approach for early-stage thoracic cancer detection.docx حسب Zhenguang Chen (518931)

"…Additionally, in a cohort of 58 cancer patients, model-predicted risk significantly decreased post-surgery (p < 0.01), indicating a strong correlation with disease burden reduction.…"

<b>Metabolic flux analysis revealed </b><b>key roles of </b><b>ArcB</b><b> in ADI pathway and IlvC in BCAA </b><b>biosynthesis </b><b>during </b><b><i>Streptococcus suis</i></b><b>... حسب Hao Tang (21218903)

"…Transcriptome analysis found a significant suppression of many central metabolic genes during anaerobic growth of <i>S. suis</i>. …"

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx حسب Maria Jordan (10265489)

"…</p>Methods<p>In silico modeling of dysregulated pathways in IPF and screening for putative interfering small molecules identified carvedilol as a promising anti-fibrotic agent. We validated drug-mediated effects on key features of fibroblast activation in functional assays and gene expression analyses in human embryonic lung fibroblasts (MRC-5). …"

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx حسب Maria Jordan (10265489)

"…</p>Methods<p>In silico modeling of dysregulated pathways in IPF and screening for putative interfering small molecules identified carvedilol as a promising anti-fibrotic agent. We validated drug-mediated effects on key features of fibroblast activation in functional assays and gene expression analyses in human embryonic lung fibroblasts (MRC-5). …"