Data Sheet 4_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx حسب Wentong Li (492392)

"…Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …"

Table 1_Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021.docx حسب Chengcheng Zhang (725743)

"…DALYs totaled 12,999,264, corresponding to an estimated annual percentage change (EAPC) of a 1.73% decrease in the age-standardized DALYs rate. …"

Scale and environmental data for the analysis of year class growth of coregonids from Lake Starnberg حسب Maxim Teichert (20796416)

"…During the observed period, phosphorus concentrations decreased, indicating reduced nutrient availability, whereas spring temperatures showed no significant long-term trend. …"

Image2_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.tif حسب Wenchao Tang (14710556)

"…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …"

Table1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.pdf حسب Wenchao Tang (14710556)

"…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …"

Image1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.png حسب Wenchao Tang (14710556)

"…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …"

Table 1_Post digestion weed seed survival in cattle.docx حسب Nebojša Nikolić (17029268)

"…No significant effects were noted for L. multiflorum, S. halepense, or A. retroflexus. …"

Image 1_Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly.png حسب Vivian Schultz (17379235)

"…</p>Results<p>Hippocampal volumes decreased from baseline to follow-up [mean APC (SD): right −1.34% (0.94), left: −1.79% (1.00)]. …"

Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes... حسب figshare admin karger (2628495)

"…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …"

Data Sheet 1_Longitudinal relationships between serum ferritin and prognosis among severe community-acquired pneumonia patients.doc حسب Jing Xu (15337)

"…</p>Results<p>The serum ferritin level was significantly increased in severe CAP patients upon initial hospitalization compared to healthy participants, and it decreased after therapy. …"

Supplementary Material for: Status of inpatients with pediatric epilepsy in children’s hospitals in China (2016–2021) حسب Wang J. (3112815)

"…The disease burden decreased from 17.26% to 12.11% with a significant upward trend (P=0.02417, R2=0.8817). …"

Effect of Gasdermin-D inhibition on CER-induced pyroptosis in P_i<i>‐</i>treated VSMCs. حسب Razia Rashid Rahil (22772495)

"…<p>Summarized bar graphs showed DIS significantly decreased mRNA expression of pyroptotic markers (A) NLRP3 (B) GSDM-D, proinflammatory cytokines (C) IL-1β (D) IL-18, and (E) Lactate dehydrogenase (LDH) release in CER treated P_i‐induced VSMCs. …"

Effect of NLRP3 inhibition on CER-induced pyroptosis in P_i<i>‐</i>treated VSMCs. حسب Razia Rashid Rahil (22772495)

"…<p>Summarized bar graphs showed MCC950 significantly decreased mRNA expression of pyroptotic markers (A) NLRP3 (B) GSDM-D, proinflammatory cytokines (C) IL-1β (D) IL-18, and (E) Lactate dehydrogenase (LDH) release in CER treated P_i‐induced VSMCs. …"

Data Sheet 1_Effects of screw-pressing temperature on the functional properties and structural characteristics of apricot (Prunus armeniaca L.) kernel protein isolates.docx حسب Li Zhang (8200)

"…These findings will collectively serve as a theoretical basis for the efficient preparation and application of API.…"

Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx حسب Yuko Horikoshi (12202859)

"…</p>Methods<p>This was a cross-sectional study conducted in 2024. We evaluated CAVI and its associated factors in 590 children aged 6–15 years (mean age: 10.5 years, 51.0% female). …"

Data Sheet 1_Body position influence on cerebrospinal fluid volume redistribution inside the cranial and spinal CSF compartments.pdf حسب I. Strbačko (20633240)

"…Introduction<p>It is generally accepted that during body position changes from horizontal to vertical there is a short-lasting shift of a certain CSF volume from the cranium into the hydrostatically lower parts of the spinal space, which leads to transitory CSF pressure decrease to negative values.…"

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF حسب Kate Beecher (6688340)

"…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …"

Data Sheet 1_Study on the function of TTG1 gene in Camellia oleifera.docx حسب Chengcheng Xiang (5512442)

"…Heterologous expression resulted in: (1) significantly increased leaf trichome density (up to 114 trichomes/50 mm²); (2) enhanced seed anthocyanin accumulation (199–318% increase); and (3) substantial alterations in fatty acid composition, including 79% elevation in oleic acid (C18:1), 113% increase in gondoic acid (C20:1), 35% reduction in both linolenic (C18:3) and palmitic acids (C16:0), and 87% decrease in erucic acid (C22:1). …"

Table 1_Petunidin alleviates diabetic nephropathy injury via the inhibition of oxidative stress and ferroptosis through the Keap1/mitoNQO1 pathway.docx حسب Yuli Qiu (21758906)

"…</p>Results<p>Keap1 expression in the kidneys of db/db mice was significantly increased, along with reduced mitochondrial translocation of NQO1, while PET reversed this trend to decrease oxidative stress and inhibit ferroptosis. …"

Datasheet1_Analysis of blood metabolite characteristics at birth in preterm infants with bronchopulmonary dysplasia: an observational cohort study.pdf حسب Yanping Guo (2467576)

"…To control for GA differences, we conducted a subgroup analysis. In the GA 24⁺⁴–27⁺⁶ weeks subgroup, we observed a significant decrease in histidine levels and the ornithine/citrulline ratio in the BPD group. …"