Data Sheet 1_Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway.docx حسب Yumei Rong (11589031)

"…Mechanism studies demonstrated that LD₄-PDT could inhibit the NF-κB signaling pathway, downregulated the expression of the inflammatory factors’ tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and myeloperoxidase (MPO), increased the contents of glutathione (GSH) and superoxide dismutase (SOD) and decreased the content of malondialdehyde (MDA). Additionally, analysis of gut microbiota revealed that LD₄-PDT treatment could decrease the abundance of the Proteobacteria phylum in fecal samples, while no significant differences were observed in the Firmicutes, Bacteroidetes, or Actinobacteria phyla among the three groups using 16S rRNA analysis.…"

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients حسب Daniel J. Zheng (16447930)

"…To date, most OER catalyst discovery has relied on human-driven approaches that have led to an understanding of only a small proportion of all possible materials. In recent years, the advent of high-throughput virtual screening and machine learning has significantly increased the space that has been explored, but methods for experimentally validating the OER activities at scale are still limited and challenging. …"

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients حسب Daniel J. Zheng (16447930)

"…To date, most OER catalyst discovery has relied on human-driven approaches that have led to an understanding of only a small proportion of all possible materials. In recent years, the advent of high-throughput virtual screening and machine learning has significantly increased the space that has been explored, but methods for experimentally validating the OER activities at scale are still limited and challenging. …"

Table 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.docx حسب Bei Li (90587)

"…Background<p>Childhood otitis media is significantly influenced by exposure to secondhand smoke (SHS), posing a considerable challenge to pediatric health. …"

Table 1_Complex evaluation of coagulation, fibrinolysis, and inflammatory cytokines in SARS-CoV-2 infected pregnant women: a prospective, case-control study.docx حسب Zsuzsa Bagoly (429210)

"…Admission IL-1β, and IL-33 were significantly lower, while IL-18 was significantly higher in cases when COVID-19 became more severe, along with significantly decreased FVIII, FXIII and plasminogen. …"

Table 1_Efficacy and safety of cadonilimab combined with AG chemotherapy in patients with unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma: a retrospect... حسب Wenke Qin (20390989)

"…</p>Results<p>The disease control rate (DCR) reached 85.7%, and the objective response rate (ORR) was 14.3%; the median progression-free survival (mPFS) was 7.87 months, and the median overall survival (mOS) was 11.45 months. Among patients with a decrease in CA19-9, the median overall survival was significantly prolonged (12.92 vs 8.89 months, P = 0.027); patients with a platelet-lymphocyte ratio (PLR) ≤ 165.62 had a significantly better mOS (12.37 vs 8.74 months, P = 0.025). …"

Comparison of hemodynamic data. حسب Seung-Jae Joo (3620240)

"…After handgrip exercise, an increase in E_LVI (<i>P</i> = 0.021) and a decrease in VAC (<i>P</i> = 0.035) were observed specifically in men, with no corresponding changes noted in women. …"

Comparison of echocardiographic data. حسب Seung-Jae Joo (3620240)

"…After handgrip exercise, an increase in E_LVI (<i>P</i> = 0.021) and a decrease in VAC (<i>P</i> = 0.035) were observed specifically in men, with no corresponding changes noted in women. …"

Minimal raw clinical data with anonymization. حسب Seung-Jae Joo (3620240)

"…After handgrip exercise, an increase in E_LVI (<i>P</i> = 0.021) and a decrease in VAC (<i>P</i> = 0.035) were observed specifically in men, with no corresponding changes noted in women. …"

Baseline characteristics of patients. حسب Seung-Jae Joo (3620240)

"…After handgrip exercise, an increase in E_LVI (<i>P</i> = 0.021) and a decrease in VAC (<i>P</i> = 0.035) were observed specifically in men, with no corresponding changes noted in women. …"

Data Sheet 1_The sigma factor σ54 (rpoN) functions as a global regulator of antibiotic resistance, motility, metabolism, and virulence in Clostridioides difficile.docx حسب Ying Yang (24175)

"…<p>Clostridioides difficile, a major cause of antibiotic-associated diarrhea and pseudomembranous colitis, is increasingly resistant to antibiotics and poses a significant threat due to its regulated virulence. …"

Data Sheet 1_Mind the road: attention related neuromarkers during automated and manual simulated driving captured with a new mobile EEG sensor system.pdf حسب Joanna Elizabeth Mary Scanlon (13913817)

"…Background<p>Decline in vigilance due to fatigue is a common concern in traffic safety. Partially automated driving (PAD) systems can aid driving but decrease the driver's vigilance over time, due to reduced task engagement. …"

Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx حسب Haoyi Yang (8215116)

"…</p>Conclusions<p>SY-009 caused a series of postprandial plasma metabolite changes in patients with T2DM, especially significant changes in the bile acid profile, which provides a new perspective on the mechanism by which SY-009 lowers blood glucose.…"

Data Sheet 1_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx حسب Haoyi Yang (8215116)

"…</p>Conclusions<p>SY-009 caused a series of postprandial plasma metabolite changes in patients with T2DM, especially significant changes in the bile acid profile, which provides a new perspective on the mechanism by which SY-009 lowers blood glucose.…"

A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets حسب Chao Li (145513)

"…HP-PRRSV has undergone significant genetic variation following nearly two decades of evolution and has transformed into a subtype referred to as HP-like PRRSV, which also exhibits high pathogenicity. …"

Data_Sheet_1_Joint association of serum sodium and frailty with mild cognitive impairment among hospitalized older adults with chronic diseases: a cross-sectional study.docx حسب Zhaozhao Hui (10221125)

"…</p>Conclusion<p>Both lower and higher serum sodium impose a significantly higher risk for MCI in older adults with frailty. …"

Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf حسب Xiaohua He (361530)

"…For CVD, stratified analyses did not show significant difference between strata. For CHF, BMI interacted with the association, with BRI being associated with decreased risk of CHF in a subgroup of normal weight subjects and increased risk of CHF in a subgroup of obese subjects. …"

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... حسب Jing Lu (120666)

"…</p>Conclusion<p>Higher SI is associated with a decreased risk of all-cause and cardiovascular mortality in CVD patients. …"

Table 2_An 8-week 24-form Tai Chi intervention on cognition in Chinese college students overusing short videos: a randomized controlled trial.xlsx حسب Yu-fan Li (22162804)

"…Post-intervention, TCG reaction times significantly decreased (p < 0.05), aligning with LCG and differing significantly from OCG. …"

Table 1_Association of serum chemokine (C–C motif) 21 and receptor (C–C motif) 7 with Hashimoto’s thyroiditis——a preliminary clinical investigation.docx حسب Xiaoting Gui (22516922)

"…</p>Results<p>Compared with the healthy control group, the Hashimoto’s thyroiditis group had significantly increased serum CCL21 [154.92 (147.01, 165.34) vs 123.74 (118.02,129.22), p<0.001] and CCR7 [19.15 (18.19, 19.71) vs 16.47 (15.88, 17.14), p<0.001], decreased free triiodothyronine, and increased thyroid stimulating hormone, TgAb, and TPOAb. …"