Image_2_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF by Kaijie Ma (6065156)

“…A common single nucleotide polymorphism (SNP) in the pro-domain of the human BDNF gene that leads to a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met) significantly decreases activity-dependent BDNF release without affecting basal BDNF secretion. …”

Image_1_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF by Kaijie Ma (6065156)

“…A common single nucleotide polymorphism (SNP) in the pro-domain of the human BDNF gene that leads to a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met) significantly decreases activity-dependent BDNF release without affecting basal BDNF secretion. …”

Table 1_Factors affecting health-seeking behavior in sports climbers in Metro Manila: a cross-sectional study.docx by Danyelle Jay T. Cruz (20772668)

“…Among the injury factors studied, the location of pain at the hip/pelvis and knee was found to be significant (p < 0.05).</p>Discussion<p>Climbers in Metro Manila have a decreased tendency to engage in health-seeking behavior. …”

Data Sheet 1_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 6_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 3_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 2_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 4_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 5_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Table 1_Gut microbiota alterations and systemic inflammation in community-acquired pneumonia: a prospective gut-lung axis study.docx by Xue-Qin Yang (3494345)

“…The abundance of short-chain fatty acid-producing genera in CAP patients decreased significantly, such as Blautia and Agathobacter. …”

List of primers used in quantitative RT-PCR. by Tarek A. Essa (22430744)

“…The results demonstrated that NPs significantly reduced basal rot symptoms and decreased the Area Under the Disease Progress Curve (AUDPC) values. …”

Data Sheet 1_Utilizing a naturopathic mouthwash with selective antimicrobial effects against multispecies oral biofilms for prevention of dysbiosis.docx by Danyal A. Siddiqui (1459219)

“…Lastly, cytocompatibility to oral rinses was tested using a 3D human fibroblast spheroid model.</p>Results<p>SL significantly inhibited the growth of disease-associated F. nucleatum and P. gingivalis 12 and 120 h, respectively, after treatment, while exhibiting lower toxicity toward commensal S. oralis, S. gordonii, and V. parvula vs. …”

Identifying hotspots of urbanization and agricultural growth: a spatio-temporal analysis of land use dynamics in Tolga, Algeria (1994–2024) by Mohamed Akram Eddine Ben Ratmia (21662098)

“…The analysis revealed a substantial transformation, with open land decreasing from 95.35% of the total area in 1994 to 82.70% in 2024, highlighting intensified land use and potential habitat fragmentation. …”

Data Sheet 1_The trends and future projections of intraocular foreign bodies among children and adolescents: a global analysis.docx by Zupeng Lu (20720147)

“…</p>Conclusion<p>The global incidence and disease burden of blindness and vision loss in children and adolescents due to IOFB have shown a slight decline from 1990 to 2021. However, there may be a significant upward trend in the future, which requires the vigilant attention of policymakers.…”

Supplementary Material for: A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma by figshare admin karger (2628495)

“…Although not curative, this therapeutic approach may play a significant role in the symptom management of these patients.…”

Table 2_Drug-induced urinary retention: a real-world pharmacovigilance study using FDA and Canada vigilance databases.xlsx by Xianyu Dai (18939514)

“…The median age among these cases was 65 years, with males comprising 53.4%. There were significant annual increases in UR reports associated with antineoplastic agents (0.19% per year) and antidiabetic drugs (0.09% per year), while reports linked to bronchodilators decreased (−0.53% per year). …”

Table 1_Drug-induced urinary retention: a real-world pharmacovigilance study using FDA and Canada vigilance databases.docx by Xianyu Dai (18939514)

“…The median age among these cases was 65 years, with males comprising 53.4%. There were significant annual increases in UR reports associated with antineoplastic agents (0.19% per year) and antidiabetic drugs (0.09% per year), while reports linked to bronchodilators decreased (−0.53% per year). …”

Data Sheet 1_Extracorporeal photopheresis as induction therapy in lung transplantation for cystic fibrosis: a pilot randomized trial.docx by Ilaria Righi (10198817)

“…Exploratory endpoint analyses revealed significant decreases in pro-inflammatory cytokines, degranulating CD8⁺ T lymphocytes, and NK cells in the treatment group. …”

Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx by Zewudu Andualem (8602434)

“…Air pollution, particularly particulate matter (PM2.5 and PM10), temperature, and altitude were reported as a significant contributor. Subgroup analysis revealed the highest prevalence in Oromia (61, 95% CI: 58–64%) and the lowest in the Southern Nations, Nationalities and People Region (23, 95% CI: 13–33%). …”

Table 1_Assessing the impact of risk perception on fisheries performance: a structural equation modeling approach in coastal fisheries.docx by Muhammad Mohsin (1335447)

“…Published literature documents such a scenario in the case of Pakistan, which results in a decreased economic contribution to the fisheries sector. …”