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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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16701
Table 4_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx
Published 2025“…Background<p>Psoriasis is a chronic immune-mediated skin disorder characterized by excessive keratinocyte proliferation and localized inflammation. …”
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16702
Data Sheet 1_An active ingredient from the combination of Corydalis Rhizoma and Paeoniae Radix Alba relieves chronic compression injury-induced pain in rats by ameliorating AR/Mboa...
Published 2025“…</p>Results<p>The results demonstrated that YB60 significantly decreased inflammatory cytokine levels both in cellular models and rat serum, while concurrently elevating pain thresholds in CCI rats. …”
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16703
Table 8_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx
Published 2025“…Background<p>Psoriasis is a chronic immune-mediated skin disorder characterized by excessive keratinocyte proliferation and localized inflammation. …”
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16704
Image 4_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif
Published 2025“…Background<p>Psoriasis is a chronic immune-mediated skin disorder characterized by excessive keratinocyte proliferation and localized inflammation. …”
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16705
Image5_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…Additionally, gain and loss experiments using a PD-L1 inhibitor (BMS-1) were conducted to investigate cellular expression profiles in vitro and cell transplantation outcomes in vivo. …”
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16706
Image6_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…Additionally, gain and loss experiments using a PD-L1 inhibitor (BMS-1) were conducted to investigate cellular expression profiles in vitro and cell transplantation outcomes in vivo. …”
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16707
Table 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.docx
Published 2024“…Furthermore, our investigations revealed a dose-dependent escalation of reactive oxygen species production, decreased mitochondrial membrane potential, and enhanced autophagy flux activity in THP1 macrophages following IL-26 treatment. …”
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16708
Differential mRNA expression of key metabolic and stress response genes in the <i>MYH7</i> Q315R mice.
Published 2025“…Clustering maps show significant changes in RNA expression (p < 0.05) greater than twofold or less than −2.0-fold (A and C). …”
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16709
Data_Sheet_1_Guanxin Danshen Formulation Protects against Myocardial Ischemia Reperfusion Injury-Induced Left Ventricular Remodeling by Upregulating Estrogen Receptor β.DOC
Published 2024“…<p>Background: Guanxin Danshen formulation (GXDSF) is a traditional Chinese herbal recipe recorded in the Chinese Pharmacopeia since 1995 edition, which consists of Salviae miltiorrhizae Radix et Rhizoma, Notoginseng Radix et Rhizoma and Dalbergiae odoriferae Lignum. …”
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16710
Depletion of viral UL87 LTF in late infection does not affect viral long promoter transcription.
Published 2025“…<b>(B)</b> UCSC Genome Browser of the MIE promoter/enhancer and downstream region show that dTag degrader treatment significantly decreased transcription from the LTF-dependent UL124 promoter and enhancer promoter EP2 (gold arrowheads). …”
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16711
DataSheet_1_FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.docx
Published 2024“…Treatment with intravenous immunoglobulin (IVIg) significantly decreases the risk of CAA, possibly through competitive binding to Fc-gamma receptors (FcγRs), which reduces the binding of pathological immune complexes. …”
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16712
Matched data.
Published 2025“…<div><p>Objective</p><p>This study aims to explore factors influencing false-negative results in Interferon-Gamma Release Assay (IGRA) for patients with Pulmonary Tuberculosis (PTB), and develop a nomogram model to predict IGRA false negatives, thereby optimizing clinical diagnosis and treatment decisions.…”
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16713
Phage–antibiotic interactions are determined by the antibiotic, not the phage.
Published 2025“…<p>(<b>a)</b> Growth curves of bacteria and phages (Bas04) in the presence of doxycycline (left) and nitrofurantoin (right). …”
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16714
Nomogram model.
Published 2025“…<div><p>Objective</p><p>This study aims to explore factors influencing false-negative results in Interferon-Gamma Release Assay (IGRA) for patients with Pulmonary Tuberculosis (PTB), and develop a nomogram model to predict IGRA false negatives, thereby optimizing clinical diagnosis and treatment decisions.…”
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16715
Data Sheet 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.zip
Published 2025“…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …”
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16716
Metabolic flux analysis revealed key roles of ArcB in ADI pathway and IlvC in BCAA biosynthesis during <i>streptococcus suis</i> anaerobic growth and infection
Published 2025“…Transcriptomic analysis found a significant suppression of many central metabolic genes during anaerobic growth of <i>S. suis</i>. …”
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16717
Numerical data underlying the graphs.
Published 2025“…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …”
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16718
Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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16719
Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa...
Published 2025“…</p>Results<p>YSHS significantly improved the general status of db/db mice, with a significant reduction in body mass, renal function indices, total cholesterol, triglycerides, and low-density lipoprotein. …”
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16720
Table 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.docx
Published 2025“…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …”