Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy by Ya-yin Tan (21448519)

“…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …”

Data Sheet 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Image 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.pdf by Jinque Luo (9645983)

“…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …”

Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx by Chunyu Yao (13559263)

“…</p>Results and discussion<p>We established three dosage groups (2.5 × 10⁸, 5 × 10⁸, and 1.5 × 10⁹ CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …”

DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf by Seungchan An (6256061)

“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”

Data Sheet 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.pdf by Jinque Luo (9645983)

“…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …”

Supporting information Abou-Kandil et al. by Olaf Kniemeyer (8561361)

“…Deletion of <i>rtaA</i> did not significantly change the ergosterol content of <i>A. fumigatus</i>, but decreased fluorescence intensity of the sterol-binding stain filipin. …”

Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx by Seungchan An (6256061)

“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”

Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx by Susan Carroll (17468)

“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”

Table 3_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Data_Sheet_1_Effects of stand age and soil microbial communities on soil respiration throughout the growth cycle of poplar plantations in northeastern China.pdf by Xiangrong Liu (380124)

“…As stand age increased, Rs showed a significant decreasing trend. We further identified r-selected microbial communities (copiotrophic species) as key biological factors influencing the decline in Rs with increasing stand age. …”

Table 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.docx by Jinque Luo (9645983)

“…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …”

Table 4_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip by Dongmei Yuan (291583)

“…In the GPL metabolism and AA metabolism pathways, the transcription levels of genes such as phospholipase A2 (PLA2) family enzymes, cyclooxygenase-2 (Cox-2), arachidonate 5-lipoxygenase (Alox5), and hematopoietic prostaglandin D synthase (Hpgds), all of which regulate phospholipid hydrolysis and lipid mediator production, were significantly increased. Additionally, we found that the expression of lysophosphatidylcholine acyltransferase 1/2 (Lpcat1/2), the enzyme regulating PC remodeling, was upregulated and that the levels of saturated PCs (PC30:0, PC32:0, and PC34:0) were simultaneously significantly increased simultaneously. …”

Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx by Susan Carroll (17468)

“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”

Data Sheet 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Table 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf by Rong Wu (152554)

“…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…”

Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif by Yaqi Cui (10798865)

“…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …”